B12 Injection (Methylcobalamin)
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- In stock
$119 $69 Your first month
Restore your B12 levels efficiently to power through your day, combat fatigue, boost metabolism, and enhance focus.
- Includes 1 x 5mL 2000mcg/mL vial with 10mg of B12
- Free expedited shipping
- Self-administered at home
- Prescribed 100% online
- Lab tested for quality
- Ongoing care at no additional cost
- No hidden fees
What is B12 (Methylcobalamin)?
Methylcobalamin is an active form of Vitamin B12, a vital nutrient crucial for numerous metabolic processes and essential for supporting key bodily functions.
What are the benefits of B12 (Methylcobalamin)?
Boost energy and combat fatigue[1]
Reduce stress levels[2]
Enhance mood and mental well-being[3]
Sharpen focus and reduce brain fog[4]
- Jatoi S, Hafeez A, Riaz SU, Ali A, Ghauri MI, Zehra M. Low Vitamin B12 Levels: An Underestimated Cause Of Minimal Cognitive Impairment And Dementia. Cureus. 2020 Feb 13;12(2):e6976. doi: 10.7759/cureus.6976. PMID: 32206454; PMCID: PMC7077099.
- Young LM, Pipingas A, White DJ, Gauci S, Scholey A. A Systematic Review and Meta-Analysis of B Vitamin Supplementation on Depressive Symptoms, Anxiety, and Stress: Effects on Healthy and ‘At-Risk’ Individuals. Nutrients. 2019 Sep 16;11(9):2232. doi: 10.3390/nu11092232. PMID: 31527485; PMCID: PMC6770181.
- Coppen A, Bolander-Gouaille C. Treatment of depression: time to consider folic acid and vitamin B12. J Psychopharmacol. 2005 Jan;19(1):59-65. doi: 10.1177/0269881105048899. PMID: 15671130.
- Wolffenbuttel BHR, Wouters HJCM, Heiner-Fokkema MR, van der Klauw MM. The Many Faces of Cobalamin (Vitamin B12) Deficiency. Mayo Clin Proc Innov Qual Outcomes. 2019 May 27;3(2):200-214. doi: 10.1016/j.mayocpiqo.2019.03.002. PMID: 31193945; PMCID: PMC6543499.
What's included?
- Includes 1 x 5mL 2000mcg/mL vial with 10mg of B12
- Syringes
- Alcohol swabs
- Doctor visit and prescription, if approved
- Ongoing care and support
- Free expedited shipping
What is B12?
Methylcobalamin is an active and bioavailable form of Vitamin B12, an essential nutrient required for energy production, nerve health, red blood cell formation, and DNA synthesis. Unlike other forms of B12, methylcobalamin is readily used by the body without needing conversion, making it highly effective in supporting metabolic processes and overall well-being. It’s especially beneficial for addressing B12 deficiencies, boosting energy, and improving mental clarity.
How B12 works
Feel more energized
Feel more energetic and stay active with enhanced energy throughout your day.
Support mental well-being
Enhance emotional health and stability for improved overall mental well-being.
Reduce stress levels
Lower stress and promote relaxation for a calmer, more balanced life.
Clear brain fog
Improve focus and clarity by reducing mental fog and enhancing cognition.
What's included in the program?
Online consultation and prescription
Medication cost and free shipping
Sterile injection kit
Ongoing clinical care and support
Lab-tested for proven results
Your medication comes from a state-licensed pharmacy within our network, arriving at your door when you need it.
To ensure quality and safety, our pharmacies use FDA and DEA-registered labs for third-party testing of every compounded batch prescribed for NiceRx patients. These lab tests verify four key characteristics related to quality and safety
Potency test
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- Passed
Sterility test
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- Passed
pH test
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- Passed
Endotoxicity
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- Passed
How NiceRx works
NiceRx makes it easy to get started with no insurance required!
Take the quiz
Complete a 2 minute health assessment to get pre-approved for treatment instantly.
Consult with a
licensed physician
Speak to a board-certified physician online to find the right medication for you.
Receive medication
Medication is delivered to your home on an ongoing basis without interruption.
Learn more about B12 injection
Is B12 injection more effective than oral tablets?
Injections offer superior bioavailability compared to oral supplements, as they bypass the digestive system and deliver B12 directly into the bloodstream to fuel your body. While oral supplements may be effective for some, the body’s ability to absorb them often decreases with age.
How often is B12 injected?
Treatment is typically started at 1ml/cc per injection once weekly. If you feel that you’re not getting the desired results, speak with your healthcare provider.
How do B12 injections help with longevity?
B12 shots are not only a fantastic way to boost energy, but they also enhance cognitive function, support vision health, and reduce the risk of age-related conditions like osteoporosis, macular degeneration, and cardiovascular disease. Additionally, B12 shots promote better sleep, and healthier skin, and nails, helping you look as good as you feel.
What are B12 injections used for?
Vitamin B12 is vital for several important bodily functions. It helps convert food into glucose, providing energy, and supports brain health by aiding in neurotransmitter production. B12 also plays a crucial role in maintaining the protective layer around nerves, promoting nerve health, and preventing anemia by supporting red blood cell production. Additionally, B12 works closely with folate (vitamin B9) in DNA and RNA synthesis, essential for the growth and function of all cells in the body.
Are B12 injections by insurance?
Unfortunately, B12 injections are not covered by insurance.
Why should I use methylcobalamin over cyanocobalamin?
Cyanocobalamin contains a cyanide molecule instead of a methyl group, making it inactive and potentially harmful. While a small portion can be converted into active B12, it may replace the body’s natural stores with inactive B12. As a result, blood tests may show normal B12 levels, even though the body is not receiving the active form it needs.
What are the side effects?
Vitamin B12 injections are generally safe, but some people may experience side effects, such as pain, redness, or swelling at the injection site, mild headaches, dizziness, nausea, or itching. Fatigue is also reported by some individuals after the injection. In rare cases, allergic reactions like difficulty breathing, swelling of the face or throat, or a fast heartbeat may occur. It’s important to consult with a healthcare provider before starting B12 injections, particularly if you have any underlying health conditions.
How long does it take to see results from B12 injections?
Depending on the dosage, some individuals experience immediate and noticeable effects as soon as the B12 starts to infuse, feeling a sense of clarity and energy. For others, it may take a few weeks for the results to become evident.
What are the storage requirements?
Store B12 injections in the refrigerator.
Your questions answered
What is NiceRx?
NiceRx is an online prescription drug savings and telehealth company that connects you with licensed U.S. clinicians and pharmacies.
How does NiceRx work?
It’s fast and easy to get started. Simply click Get Started to complete an online quiz to find out if you are eligible for treatment. If eligible, you can check out and submit your shipping address and payment details. You will schedule a time that is convenient for you to have an online visit with a licensed U.S. provider.
A licensed healthcare provider will provide a custom dosing and treatment plan tailored to your individual needs.
If approved, you will be billed monthly and receive an ongoing supply of medication from a licensed U.S. pharmacy. You can cancel at any time.
Does NiceRx require insurance?
No, NiceRx does not require insurance. You can order from NiceRx whether or not you have insurance.
How is NiceRx responding to drug shortages?
NiceRx and its affiliated healthcare providers are taking measures to assist patients in their weight loss journey. Providers may personalize the treatment plan for patients if deemed clinically appropriate. These adjustments could involve prescribing alternative GLP-1 medications, customized dosing and formulations, and working collaboratively on a personalized treatment plan, in combination with diet, lifestyle, and fitness activities.
If a provider decides that a GLP-1 medication is medically appropriate, the sooner a patient joins the program, the quicker our team can work towards assisting you with your weight loss journey.
What states is NiceRx available?
NiceRx is currently available in all states except for New York and Kansas.
If service is currently unavailable in your state, you can sign up to a waiting list to be notified when service is available in your state.
What medications are available and what do they cost?
NiceRx offers personalized treatment plans that are prescribed by a licensed U.S. healthcare provider if medically appropriate. All medications are shipped by a licensed U.S. pharmacy.
Currently, NiceRx offers the following medications:
- Compounded semaglutide + B6 (same active ingredient as Ozempic® and Wegovy®) up to 2.4 mg/weekly – $249/month
- Compounded tirzepatide + B6 (same active ingredient as Mounjaro® and Zepbound®) with B6 up to 9.5 mg/weekly – $349/month
Get started today and get $50 off your first month.
Who is qualified?
A licensed healthcare provider will review your health history and goals when deciding if a prescription medication is appropriate for you.
Is it safe?
Our partner pharmacies are state-licensed and comply with state and federal regulations for compounding medications. Compounding pharmacies are routinely inspected for quality, potency, efficacy and safety. If approved for a prescription, the medication is shipped directly to your home in discreet packaging. We offer free expedited shipping at no additional cost.
Do you provide ongoing care?
Yes, ongoing care is provided at no additional cost. We are available to answer any questions. You can also schedule a follow up visit with your provider to discuss any adjustments to your treatment plan.
What should I do in case of an emergency?
In case of an emergency, you should immediate call 911 or visit an urgent care or Emergency Department.
What is the cancellation and refund policy?
You can cancel the service at any time. While we are unable to accept returns, we are committed to addressing any of your concerns.
Important safety information and common side effects
Vitamin B12 supplements are generally safe when taken at appropriate doses. The recommended daily intake for adults is 2.4 micrograms, but higher doses are also considered safe, as your body absorbs only what it needs, and any excess is passed through urine.
The most common side effect of B12 injections is discomfort at the injection site. If this occurs, try changing the injection location or reducing the frequency. B12 injections should be avoided during pregnancy, breastfeeding, or if you plan to become pregnant or breastfeed soon. High doses of B12, often used to treat deficiencies, may cause side effects such as headaches, nausea, diarrhea, fatigue or weakness, and tingling in the hands and feet.
Note: The above statements have not been evaluated by the FDA (U.S. Food and Drug Administration). This product is not intended to diagnose, treat, cure, or prevent any disease.
Prescription products require an online consultation with a licensed medical provider who will assess your health and determine if a prescription is appropriate for you. Benefits described are based on third party studies. Medications are offered as a subscription service which can be cancelled at any time. The product packaging may be different than shown on this website.