How much does Entresto cost with Medicare

In 2022, the manufacturer of Entresto (Novartis) states that around 80% of individuals with Medicare Part D prescription drug plans pay less than $50 per month in out-of-pocket costs for Entresto, and over 50% of people with Medicare Part D pay $10 or less for their Entresto prescription each month. That’s a significant saving compared to uninsured individuals who pay the full list price of $623.69 for Entresto, as stated on the manufacturer’s (Novartis) website.

The amount an individual pays for Entresto with prescription insurance coverage depends on various factors such as:

  • the type of Medicare coverage
  • the formulary tier (list of covered drugs in the plan)
  • whether the individual has reached their annual deductible amount
  • coinsurance or copayments

What is Entresto?

Entresto (sacubitril/valsartan) is an FDA-approved prescription medication used to treat heart failure. It’s a combination of two drugs: sacubitril and valsartan. Sacubitril is an inhibitor of neprilysin, while valsartan is an angiotensin receptor blocker (ARB). This combination works by widening blood vessels and reducing the amount of water and salt retained in the body. Entresto relaxes blood vessels and reduces blood pressure. It helps to reduce the risk of cardiovascular death and hospitalization in individuals with chronic heart failure.

The CDC estimates that there are around 6.2 million adults in the United States who have heart failure. If you have been diagnosed with heart failure, it’s important to talk to your doctor about whether Entresto may be right for you. As always, be sure to thoroughly discuss any potential side effects and other considerations before starting treatment.

Is there a generic version of Entresto?

There is currently no generic version of Entresto available on the market. Individuals who are prescribed this medication will need to purchase the brand-name drug, Entresto.

Does Medicare cover Entresto?

Novartis, the manufacturer, estimates that Entresto has preferred coverage for more than 99% of people with Medicare, on average.

However, note that Medicare Part A (hospital insurance) does not cover Entresto because it is not a hospital-administered medication. As well, Medicare Part B (medical insurance) does not cover Entresto because it is considered an outpatient medication.

Medicare Part D plans (prescription drug plans) and Medicare Advantage plans with prescription drug coverage (MAPDs) may cover Entresto. However, the coverage and costs will vary depending on your specific insurance plan. To learn more about whether Medicare covers Entresto, talk to your healthcare provider or contact Medicare directly for more information about your Medicare Part D coverage. They can help you determine what level of coverage is available for Entresto under your specific plan.

Get your Entresto medication for only $49 per month

Get Started

Medicare Part D plans and Entresto coverage

Each Medicare prescription drug plan has its own rules about how much it will cover for each type of drug in its formulary (list of covered drugs). Some plans may place Entresto on a higher tier of their formulary (list of covered drugs), which means that patients will have to pay a higher coinsurance or copayment for the medication. Other plans may exempt Entresto from the annual deductible amount.

If an individual has a Medicare Part D prescription drug plan or a Medicare Advantage Prescription Drug (MAPD) plan, they will likely pay a monthly premium, an annual deductible, and coinsurance or copayments for their Entresto prescription medication. No Medicare drug plan may have a deductible of more than $480 in 2022 which means that you are responsible for the first $480 of out-of-pocket costs for your prescription drugs before your coverage commences. In the Donut Hole (also known as the Coverage Gap) stage, there is a temporary limit to what Medicare will cover for your prescription medication. As such, you may pay more for this medication until you have met your annual deductible amount.

Medicare Part D prescription drugs are the most common way of obtaining coverage from Medicare for prescription drugs such as Entresto. If an individual has Medicare Part D, also called prescription drug coverage, they may be able to get Entresto at a lower cost. Part D plans have a list of covered drugs (formulary drug list) and use tiered formularies. The cost of Entresto depends on which tier the drug is placed in the health insurance company’s formulary and may require prior authorization from your insurance company.

Entresto and Medicare Advantage

Medicare Advantage plans (Medicare Part C) are an alternative to the Original Medicare. If the Medicare Advantage plan includes prescription drug coverage, it may be possible to obtain Entresto at a lower cost. Advantage plans use tiered formularies and the cost of Entresto depends on which tier the drug is placed in the health insurance company’s formulary.

If you are interested in learning more about how much Entresto costs with Medicare, speak to your healthcare provider or contact Medicare directly for more information about their Part D coverage of this medication.

Can Medigap plans help me save money on Entresto?

No, it is not possible to use Medicare Supplement Insurance (Medigap) with prescription drugs. Medigap plans are supplemental insurance plans that may help cover some of the costs that Original Medicare does not cover, such as copayments, coinsurance, and deductibles.

How much does Entresto cost with Medicare?

The cost of Entresto will vary depending on a number of factors, including insurance coverage and the pharmacy you use.

In 2022, the drug manufacturer of Entresto (Novartis) states around 80% of individuals with Medicare Part D prescription drug plans pay less than $50 per month in out-of-pocket costs for Entresto, and over 50% of people with Medicare Part D pay $10 or less for their Entresto prescription each month, according to the manufacturer, Novartis.

Entresto assistance for Medicare patients

If you have Medicare and need help paying for your Entresto prescription medication, there are a few options that might be able to help you save money.

  • With the Entresto Co-Pay Card, you may be eligible to pay as little as $10 for a 30, 60, or 90 day supply of Entresto. You can bring your co-pay card along with your prescription to a participating pharmacy. The offer from the manufacturer is not valid under Medicare, Medicaid, or any other federal or state program. To see if you qualify for this program, visit the manufacturer’s website or speak with your doctor.
  • Novartis, the manufacturer of Entresto, offers a free trial offer which is available for all patients regardless of insurance coverage. To redeem this offer, patients are required to present this offer at a participating pharmacy along with a valid Entresto prescription from their healthcare provider. The voucher is valid for 30 days (up to a maximum of 60 tablets).
  • Enrollment in Patient Assistance Programs (PAPs) is also an option to help you pay for Entresto.
  • You may also be eligible for Extra Help. Extra Help is a program from the Social Security Administration that helps people with limited incomes and resources pay for their Medicare prescription drug costs. To see if you qualify for Extra Help, visit the Social Security Administration’s website or call 1-800-772-1213.
  • If you cannot afford your medication, your doctor may be able to provide you with samples of Entresto from the manufacturer.

Medically reviewed

A medical professional has reviewed this article.

Jamie Winn, PharmD
Jamie Winn, PharmD

Jamie Winn, PharmD

Medical Writer & Reviewer

Jamie Winn, PharmD

Medical Writer & Reviewer

Dr. Jamie Winn received his Doctor of Pharmacy in 2002 from the University of South Carolina College of Pharmacy, Columbia, SC. Jamie is a medical reviewer for NiceRx.