Most common
More serious
Most common
More serious
You should not use Gemtesa if you:
You should talk to your doctor before using Gemtesa if you:
You should not use Myrbetriq if you:
You should talk to your doctor before using Myrbetriq if you:
Once daily
Based on the condition treated and body weight
30, 75 mg Gemtesa tablets 75 mg will cost around $490
30, 50 mg Myrbetriq tablets will cost around $540
Overactive bladder (OAB) is a common condition causing urinary urgency, frequency, and leakage. The key symptom is the sudden desire to urinate that is difficult to suppress. Historically, anticholinergics and antimuscarinics have been used to treat overactive bladder (OAB). However, these therapies have been shown to have side effects, such as dry mouth, drowsiness, constipation, dizziness, and confusion, as well as an increase in the risk of cognitive impairment and dementia.
Gemtesa and Myrbetriq are prescription drugs used for the treatment of overactive bladder. Here we will explain how they work, their similarities and differences, their side effects, and more. This should provide you with the basics to better understand your options.
Gemtesa is manufactured by Urovant Sciences, Inc. It has FDA approval (U.S. Food and Drug Administration) for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, incontinence episodes, and urinary frequency in adults.
Vibegron is a beta-3 adrenergic agonist that works by relaxing a certain bladder muscle (detrusor, a smooth muscle in the wall of the bladder) which helps to increase bladder capacity and lessens symptoms of overactive bladder.
Gemtesa is available in tablet form, in the following doses: 75 mg.
The recommended dose is one 75 mg tablet once daily. Swallow the tablet whole with a full glass of water, with or without food. Tablets may be crushed and mixed with applesauce.
Always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.
Myrbetriq is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Astellas Pharma US, Inc. Myrbetriq is also a prescription medication used to treat OAB symptoms in adults. Myrbetriq helps relax your bladder muscles, providing relief from the symptoms of an overactive bladder.
The active ingredient in Myrbetriq is called mirabegron. Mirabegron relaxes the muscles in the wall of your bladder (detrusor urinae muscle) to reduce the symptoms of an overactive bladder. It does this by attaching itself to areas on the surface of the muscles called β3-adrenergic receptors. These receptors are stimulated by mirabegron, starting a process that relaxes the bladder muscles.
Myrbetriq is available in extended-release tablet form, in the following doses: 25 mg and 50 mg.
The recommended starting dose is 25 mg once daily, alone or in combination with solifenacin succinate 5 mg, once daily. The dose may be increased to 50 mg once daily. Swallow the tablets whole with water, with or without food, do not chew, divide or crush. For patients with severe renal or hepatic impairment, the maximum dose is 25 mg once daily.
The most common side effects of Gemtesa in clinical trials compared to placebo include:
More serious side effects of Gemtesa include:
The most common side effects of Myrbetriq in clinical trials compared to placebo include:
More serious side effects of Myrbetriq include
These aren’t all the side effects Gemtesa or Myrbetriq can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about adverse effects, talk to your physician or pharmacist.
Gemtesa can interact with other medications. These include:
Myrbetriq can interact with other medications. These include:
Gemtesa and Myrbetriq can interact with other medications. This can change how Gemtesa and Myrbetriq and other medications work and can make side effects more likely. Tell your prescribing physician about all your drugs, including vitamins and dietary supplements.
You should not use Gemtesa if you:
Talk to your doctor about your medical condition before using Gemtesa if you:
You should not use Myrbetriq if you:
Talk to your physician before taking Myrbetriq if you:
If you have any concerns about Gemtesa or Myrbetriq side effects, talk to your physician, or pharmacist for medical advice. Also inform your healthcare provider about any medical conditions, supplements, and over-the-counter meds you are taking. You are also encouraged to report side effects to the FDA: visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.
