- Type 2 diabetes
$49 per month
- Type 2 diabetes
$49 per month
Drug facts and comparison
You should not use Ozempic if you:
You should talk to your doctor before using Ozempic if you:
You should not use Trulicity if you:
You should talk to your doctor before using Trulicity if you:
0.25mg once weekly
0.5mg once weekly
1mg once weekly
0.75mg once weekly
1.5mg once weekly
3mg once weekly
4.5mg once weekly
2 mg/1.5 ml pre-filled Ozempic Pen costs $899 on average for 1.5 milliliters
0.75 mg/0.5 ml pre-filled Trulicity Pen costs $891 on average for 2 milliliters
Ozempic and Trulicity are brand-name prescription drugs for type 2 diabetes commonly taken with metformin to help lower your blood glucose levels. They also help lower your risk for heart attack, stroke, and death from heart disease. Ozempic is manufactured by Novo Nordisk and Trulicity is manufactured by Eli Lilly.
It is not always easy to know how these medications work and the differences between them. Your doctor will prescribe you the most appropriate medication for your needs, but it is still important to better understand the diabetes drugs available to you.
Both Ozempic and Trulicity are injectable type 2 diabetes medications approved by the Food and Drug Administration (FDA). But are they the same? Here we focus on Ozempic vs Trulicity and explain clearly and simply what they are, how they work, and the similarities and differences between them.
Ozempic and Trulicity belong to a drug class called GLP-1 (glucagon-like peptide-1) receptor agonists. When you eat and drink, your body produces digestive hormones called incretins. GLP-1 is one of these incretin hormones.
GLP-1 incretin hormones help lower your blood glucose levels when you digest food in three ways. They:
Ozempic and Trulicity act in the same way as GLP-1 incretin hormones. By stimulating the same receptors, they cause your body to release more insulin, less glucagon, and digest food slower.
Trulicity and Ozempic are more active when you have consumed food and are digesting it. They become less active when you stop eating or drinking. They help to ensure your blood glucose levels do not fall too low causing hypoglycemia. Trulicity and Ozempic can not be used to treat type 1 diabetes.
So, what is the difference between Trulicity and Ozempic? Both are GLP-1 receptor agonist medications used to treat type 2 diabetes. They are given as an injection under the skin (subcutaneous injection) using a self-injecting pen device, and they work in the same way. Although Ozempic and Trulicity are similar, there are key differences between them.
The active ingredients they contain are the most important difference between Ozempic and Trulicity. Ozempic contains a GLP-1 receptor agonist called semaglutide, while Trulicity contains a GLP-1 receptor agonist called dulaglutide. Semaglutide and dulaglutide do work in similar ways, but they are not identical and you may respond to them differently.
The doses prescribed for each drug also vary. Ozempic pens can be prescribed in 0.25 mg, 0.5 mg, and 1 mg doses, whereas Trulicity pens can be prescribed in larger 0.75 mg, 1.5 mg, 3 mg, and 4.5 mg doses. Ozempic is typically taken in smaller doses, as independent research has shown it to be more effective than Trulicity.
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Both Ozempic and Trulicity are proven and effective treatments for type 2 diabetes. However, in the SUSTAIN 7 clinical trial that compared the two medications, Ozempic was found to be more effective than Trulicity. The study was conducted on 1,201 patients with type 2 diabetes from 194 hospitals in 16 countries. Over the 40-week trial, Ozempic lowered blood glucose levels further than Trulicity on average and caused more weight loss. No noteworthy differences in side effects were found between Ozempic and Trulicity.
Although Ozempic was found to be more effective than Trulicity, it is important to note that people respond to medications differently. This means some people will get better results from Trulicity and some from Ozempic.
The American Diabetes Association (ADA) recommends using a glucagon-like peptide-1 (GLP-1) agonist, such as Ozempic or Trulicity, in adults with type 2 diabetes who also have cardiovascular disease or kidney disease.
Ozempic and Trulicity both belong to the same class of medication hence, they both have similar common gastrointestinal side effects such as:
In rare instances, Ozempic and Trulicity can cause more serious side effects, including:
For medical advice about side effects, talk with your health care provider and also read the medication guide and instructions for use that comes with Ozempic.
RELATED: Ozempic side effects, Trulicity side effects
Don’t take Ozempic or Trulicity if you:
Talk to your doctor before taking Ozempic if you:
Always speak to your healthcare provider for medical advice regarding drug interactions, taking supplements, taking over-the-counter medications, and drinking alcohol when using Ozempic or Trulicity. Healthcare professionals are the most reliable and accurate source of drug information.
Trulicity and Ozempic are both GLP-1 receptor agonist medications used to treat type 2 diabetes mellitus. Although similar, they are different medications that contain different active ingredients. Dulaglutide in Trulicity and semaglutide in Ozempic. The two medications may also affect you differently.
Ozempic and Trulicity are similar medications that can help to reduce your blood sugar levels in the same way. However, independent research that compared the two medications, found that Ozempic lowered blood glucose levels further than Trulicity. It also caused more weight loss.
RELATED: Ozempic for weight loss
Trulicity belongs to a class of Type 2 diabetes medications called GLP-1 receptor agonists. Other GLP-1 receptor agonists include Bydureon, Byetta, Ozempic, Rybelsus (oral medication of Ozempic), Tanzeum, and Victoza.
Ozempic begins working as soon as you take it. It can take 5 to 8 weeks before you see a noticeable drop in your blood glucose, and up to 6 months for it to be most effective. Ozempic should be taken alongside changes to your diet and exercise. You will get better results faster if you stick to your diet and exercise program.
Trulicity can be taken over the long term. It is important to note that you may need to stop using Trulicity if it causes you severe side effects, or if it does not work effectively for you.
The price paid for Ozempic and Trulicity will depend on your insurance status, the number of self-injecting pens, the strength you buy, as well as where you buy them. Average prices for Ozempic and Trulicity prices are similar, but Ozempic is usually slightly more expensive.
While Ozempic and Trulicity are similar GLP-1 receptor agonist medications used to treat Type 2 diabetes, there are differences between them. Whichever medication you have been prescribed is the one that you should take.
If your doctor has prescribed Ozempic or Trulicity to you, you may be able to receive your medication for $49 per month with NiceRx. Complete our online enrollment application to find out if you are eligible for Trulicity or Ozempic assistance.