
Compounded Semaglutide +B6
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- In stock
$249 $199 Your first month
Once-weekly GLP-1 prescription injection, customized for individuals with vitamin B6 which can support energy levels, digestion and nausea. Dosages are personalized and adjusted under doctor supervision for optimal outcomes.
- Includes medication cost, access to provider and free shipping
- Personalized weight loss treatment plan
- Same price for all doses
- Ongoing care at no additional cost
- No insurance required
- Lab tested for quality
- No hidden fees
What is compounded semaglutide + B6?
Compounded semaglutide + B6 is a GLP-1 medication used for chronic weight management. It’s combined with vitamin B6 which can support energy levels, digestion, and nausea.
Compounding involves creating personalized medications to meet specific patient needs, such as making a liquid form of a drug typically available only as a pill or addressing shortages of FDA-approved medications.
Compounded drugs are prepared by state-licensed pharmacies following state and federal guidelines but are not FDA-approved or evaluated for safety or effectiveness.
NiceRx partners with compounding pharmacies to provide compounded semaglutide products with B6, using semaglutide base rather than semaglutide salts.
Where is compounded semaglutide + B6 made?
NiceRx works with state-licensed compounding pharmacies that make compounded semaglutide + B6 for you. Compounding pharmacies are regulated by their state boards of pharmacy and are required to comply with state and federal laws and quality standards.
Is compounded semaglutide + B6 safe?
We work with state-licensed compounding pharmacies that adhere to strict regulatory requirements to ensure quality medications for our patients.
How do I use the medication?
Compounded GLP-1 medications like semaglutide + B6 are injected once weekly in the fatty layer under the skin of the stomach, thigh, or upper arm. If prescribed, you will receive usage instructions including details on how to use the medication.
Potential side effects
The most common side effects with GLP-1 medications including compounded semaglutide + B6 are gastrointestinal-related such as nausea, diarrhea, and vomiting.
Is compounded semaglutide + B6 available in my state?
Compounded semaglutide + B6 through NiceRx is currently available in all states except for New York and Kansas.
If service is currently unavailable in your state, you can sign up to a waiting list to be notified when service is available in your state.
As an alternative to FDA-approved brand name products, a provider may prescribe a compounded drug where medically appropriate after an online consultation. Providers may prescribe compounded drugs as needed to meet patient requirements or drug shortages. Compounded drugs are prepared by a state-licensed compounding pharmacy partner and are permitted under federal law, however, they are not approved by the FDA and do not undergo safety, effectiveness, or manufacturing review. Results may vary. Plans are available as a subscription and you can cancel at any time. Actual product packaging might differ from the images displayed.
*Safety info: GLP-1 drugs may have serious side effects, including possible thyroid tumors. Do not use GLP-1 drugs if you or your family have a history of thyroid cancer called MTC or MEN 2. See more important safety information.

What is compounded semaglutide + B6?
Compounded semaglutide + B6 is a weekly injection for weight loss. It’s customized with B6 which can support energy levels, digestion and nausea. Working with state-licensed compounding pharmacies, NiceRx offers safe and affordable access to compounded semaglutide + B6, a GLP-1 weight loss medication. While the compounded medication doesn’t come in prefilled pens, there’s no need to worry as NiceRx will help you understand how to use the medication.
How semaglutide + B6 works
Mimics gut hormones

Semaglutide + B6 mimics the hormone GLP-1.
Slows digestion

The GLP-1 hormone helps lower blood sugar levels and slows food from entering the intestine.
Suppresses appetite

It affects appetite and satiety in the brain.
What's included in the program?

Online consultation and prescription

Medication cost and free shipping

Sterile injection kit

Ongoing clinical care and support

Lab-tested for proven quality
Your medication comes from a state-licensed pharmacy within our network, arriving at your door when you need it.
These lab tests verify four key characteristics related to quality and safety:
Potency test
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- Passed

Sterility test
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- Passed

pH test
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- Passed

Endotoxicity
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- Passed

How NiceRx works
NiceRx makes it easy to get started with no insurance required!
Take the quiz
Complete a 2 minute health assessment to get pre-approved for treatment instantly.

Consult with a
licensed physician
Speak to a board-certified physician online to find the right medication for you.

Receive medication
Medication is delivered to your home from a licensed U.S. pharmacy on an ongoing basis without interruption.

Learn more about compounded semaglutide + B6
What is compounded semaglutide + B6?
Compounded semaglutide + B6 is used for chronic weight management. It’s a customized formulation which can support energy levels, digestion and nausea.
Compounding is a process that involves creating a medication that is specific to the needs of a patient when either the medication is unavailable in the required form or dose, or when the FDA-approved medication is in short supply in the marketplace.
Compounded medications are made by state-licensed compounding pharmacies that adhere to state and FDA requirements and quality standards for compounding medications. Compounded drugs are not FDA-approved and do not have to undergo any safety, effectiveness, or manufacturing reviews.
NiceRx works with state-licensed compounding pharmacies that supply compound semaglutide base form (not semaglutide salts) with vitamin B6.
Where is compounded semaglutide + B6 made?
NiceRx works with state-licensed compounding pharmacies that make compounded semaglutide + B6 in compliance with state and federal laws. Compounding of medications is regulated by the FDA and state boards of pharmacy and the compounding pharmacy is required to adhere to state and federal laws.
What are the dosing guidelines for compounded semaglutide + B6?
For people starting on compounded semaglutide + B6, the treatment is typically started at a low dose and gradually increased over time until a suitable maintenance dose is reached. If a prescription is approved, the healthcare provider will determine a personalized dosing schedule for you.
How do you use compounded semaglutide + B6?
Compounded semaglutide + B6 is supplied in a small multi-dose vial alongside syringes that you will prepare for your weekly dose to safely self-administer.
To prepare each weekly dose, use the alcohol swab provided to clean the top of the vial, and then carefully draw the prescribed amount of medication into the syringe. Compounded semaglutide + B6 should be injected once per week (on the same day) under the skin of your abdomen (stomach), thigh or upper arm.
You’ll receive instructions that explain how to safely use the medication.
Are compounded GLP-1s covered by insurance?
Unfortunately, compounded GLP-1s are typically not covered by insurance.
How much does compounded semaglutide + B6 cost?
Compounded semaglutide + B6 through the NiceRx Weight Loss Program costs $249/month regardless of the dose. This price includes the cost of medication, shipping, syringes, the initial provider visit and up to one monthly follow-up visit.
Can I get compounded semaglutide + B6 in my state?
Compounded semaglutide + B6 through NiceRx is currently available in all states except for New York and Kansas.






Your questions answered
What is NiceRx?
NiceRx is an online prescription drug savings and telehealth company that connects you with licensed U.S. clinicians and pharmacies.
How does NiceRx work?
It’s fast and easy to get started. Simply click Get Started to complete an online quiz to find out if you are eligible for treatment. If eligible, you can check out and submit your shipping address and payment details. You will schedule a time that is convenient for you to have an online visit with a licensed U.S. provider.
A licensed healthcare provider will provide a custom dosing and treatment plan tailored to your individual needs.
If approved, you will be billed monthly and receive an ongoing supply of medication from a licensed U.S. pharmacy. You can cancel at any time.
Does NiceRx require insurance?
No, NiceRx does not require insurance. You can order from NiceRx whether or not you have insurance.
How is NiceRx responding to drug shortages?
NiceRx and its affiliated healthcare providers are taking measures to assist patients in their weight loss journey. Providers may personalize the treatment plan for patients if deemed clinically appropriate. These adjustments could involve prescribing alternative GLP-1 medications, customized dosing and formulations, and working collaboratively on a personalized treatment plan, in combination with diet, lifestyle, and fitness activities.
If a provider decides that a GLP-1 medication is medically appropriate, the sooner a patient joins the program, the quicker our team can work towards assisting you with your weight loss journey.
What states is NiceRx available?
NiceRx is currently available in all states except for New York and Kansas.
If service is currently unavailable in your state, you can sign up to a waiting list to be notified when service is available in your state.
What medications are available and what do they cost?
NiceRx offers personalized treatment plans that are prescribed by a licensed U.S. healthcare provider if medically appropriate. All medications are shipped by a licensed U.S. pharmacy.
Currently, NiceRx offers the following medications:
- Compounded semaglutide + B6 – $249/month
- Compounded tirzepatide + B6 up to 9.5 mg/weekly – $349/month
Get started today and get $50 off your first month.
Who is qualified?
A licensed healthcare provider will review your health history and goals when deciding if a prescription medication is appropriate for you.
Is it safe?
Our partner pharmacies are state-licensed and comply with state and federal regulations for compounding medications. Compounding pharmacies are routinely inspected by authorized regulatory bodies in their state. If approved for a prescription, the medication is shipped directly to your home in discreet packaging. We offer free expedited shipping at no additional cost.
Do you provide ongoing care?
Yes, ongoing care is provided at no additional cost. We are available to answer any questions. You can also schedule a follow up visit with your provider to discuss any adjustments to your treatment plan.
What should I do in case of an emergency?
In case of an emergency, you should immediate call 911 or visit an urgent care or Emergency Department.
What is the cancellation and refund policy?
You can cancel the service at any time. While we are unable to accept returns, we are committed to addressing any of your concerns.
Medication disclaimers
Compounded semaglutide + B6
Compounded semaglutide + B6 is an injectable glucagon-like peptide-1 (GLP-1) prescription drug that can help people with obesity (BMI ≥30) or overweight (BMI ≥27) to lose weight and keep it off. This medication should be used in combination with a reduced-calorie diet and increased physical activity.
Semaglutide + B6 is injected subcutaneously once weekly. Semaglutide + B6 is typically initiated at a low dose and is gradually increased over time.
If the patient does not tolerate a specific dose during the dose escalation period, consider delaying the dose escalation for 4 weeks.
You can administer at any time of the day, on the same day each week, with or without meals. Inject subcutaneously in the stomach (abdomen), thigh, or upper arm, and make sure to change the injection site with each dose.