compareNasacort AQ vs Flonase

Nasacort AQ vs Flonase

Drug facts and comparison

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Medically reviewed by  Jamie Winn, PharmD

Nasacort AQ

triamcinolone acetonide

Flonase

fluticasone propionate

Uses

  • Management of nasal symptoms of seasonal and perennial allergic rhinitis in adults and children 2 years of age and older
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$49 per month
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  • Management of nasal symptoms of perennial nonallergic rhinitis in adult and pediatric patients aged 4 years and older
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$49 per month
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Summary

Brand name: Nasacort AQ
Brand name: Flonase
Manufacturer: Sanofi-aventis
Manufacturer: GlaxoSmithKline
Active ingredient: triamcinolone acetonide
Active ingredient: fluticasone propionate
Indication: Nasal symptoms of seasonal and perennial allergic rhinitis in adults and children 2 years of age and older
Indication: Management of nasal symptoms of perennial nonallergic rhinitis in adult and pediatric patients aged 4 years and older

Side Effects

Most Common

  • Pharyngitis
  • Epistaxis
  • Flu syndrome
  • Increased cough
  • Bronchitis
  • Dyspepsia
  • Tooth disorder
  • Headache
  • Pharyngolaryngeal pain
  • Nasopharyngitis
  • Abdominal pain, diarrhea

More serious

  • Candida albicans infection
  • Nasal septal perforation
  • Impaired wound healing
  • Glaucoma and Cataracts
  • Immunosuppression
  • Hypothalamic-pituitary-adrenal (HPA) axis effects – growth reduction

Most Common

  • Headache
  • Pharyngitis
  • Epistaxis
  • Nasal burning
  • Nasal irritation
  • Nausea, vomiting
  • Asthma symptoms
  • Cough

More serious

  • Candida infection
  • Nasal ulceration
  • Nasal septal perforation
  • Impaired wound healing
  • Glaucoma and cataracts
  • Hypersensitivity reactions including anaphylaxis, angioedema, urticaria, contact dermatitis, and rash
  • Immunosuppression
  • Hypercorticism and adrenal suppression
  • Reduction in growth

Drug Interactions

Severe interactions
  • No severe interactions
Serious interactions
  • HIV protease inhibitors – atazanavir, indinavir, ritonavir, saquinavir
  • Antifungals – ketoconazole, itraconazole, miconazole
  • Antibiotics – clarithromycin, erythromycin
Moderate interactions
  • No moderate interactions
Severe interactions
  • HIV protease inhibitors – atazanavir, indinavir, ritonavir, saquinavir
  • Antibiotics – clarithromycin
  • Antifungals – ketoconazole, itraconazole
Serious interactions
  • Antiarrhythmics – dronedarone
  • Calcium channel blockers – diltiazem, verapamil
  • Antifungals – fluconazole
Moderate interactions
  • Antibiotics – erythromycin

Warnings

You should not use Nasacort AQ if you:

  • Are allergic to the active ingredient triamcinolone acetonide
  • Have had an allergic reaction to any of the other ingredients in Nasacort AQ
  • Are younger than 2 years of age

Talk to your physician before taking Nasacort AQ if you:

  • Are taking any of the medications that could interact with Nasacort AQ
  • Have liver problems
  • Have kidney problems
  • Have heart problems
  • Have adrenal problems
  • Have asthma
  • Have cataracts or glaucoma
  • Have had recent exposure to chicken pox
  • Have Herpes simplex infection of the eye
  • Have any other type of infection
  • Have sores or ulcers in the nose
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should not use Flonase if you:

  • Are allergic to the active ingredient fluticasone
  • Have had an allergic reaction to any of the other ingredients in Flonase
  • Are younger than 4 years of age

Talk to your physician before taking Flonase if you:

  • Are taking any of the medications that could interact with Flonase
  • Have had recent nose surgery or injury to the nose
  • Have sores or ulcers in the nose
  • Have cataracts or glaucoma
  • Have liver problems
  • Have diabetes
  • Have a weak immune system
  • Have any other type of infection

Dosage

One or two sprays in each nostril once daily

One or two sprays in each nostril once daily

Cost

10.8 milliliters (55 mcg/inh), Nasacort nasal spray will cost around $28

9.9 milliliters (50 mcg/inh) Flonase nasal spray will cost around $22

FAQs

Flonase Allergy Relief and Nasacort Allergy 24 hr are brand names for prescription drugs containing corticosteroid/steroid nasal sprays for the treatment of hay fever, perennial allergic rhinitis, and allergies.

Flonase and Nasacort both contain glucocorticoid corticosteroids that help to relieve sinus problems (nasal allergy symptoms) such as nasal congestion, a runny nose or itchy nose, sneezing, postnasal drip, and other allergy symptoms, including eye symptoms such as itchy eyes or watery eyes. Here we will explain how they work, their similarities and differences, their side effects, and more.

What is Nasacort?

Nasacort is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Sanofi-Aventis U.S. LLC. It contains the active ingredient triamcinolone acetonide, a corticosteroid used to treat the nasal symptoms of seasonal allergies and perennial allergic rhinitis in adults and children 2 years of age and older.

Nasacort dosage

Nasacort is available as a nasal spray, in the following doses: 55 mcg triamcinolone acetonide in each spray.

For adults and adolescents older than 12 years of age, the starting and the maximum dose is 220 mcg/day (two sprays in each nostril once daily). For children 6 to 12 years of age, the starting dose is 110 mcg/day (one spray in each nostril once daily). For children 2 to 5 years of age, the starting and the maximum dose is 110 mcg/day (one spray in each nostril once daily).

What is Flonase?

Flonase is an FDA (U.S. Food and Drug Administration) approved medication manufactured by GlaxoSmithKline. It contains fluticasone propionate as the active ingredient, a corticosteroid used to manage the nasal symptoms of perennial nonallergic rhinitis in adult and pediatric patients 4 years of age and older.

Flonase dosage

Flonase is available as a nasal spray, in the following doses: 50 mcg of fluticasone propionate in each 100-mg spray.

Flonase is for intranasal use only. The recommended starting dose for adults is 2 sprays per nostril once daily. For adolescents and children aged 4 years and older, the recommended dose is 1 spray per nostril once daily (100 mcg per day).

Common side effects of Nasacort and Flonase

The most common side effects of Nasacort in clinical trials include:

  • Sore throat
  • Nose bleeds
  • Flu syndrome
  • Cough
  • Bronchitis
  • Dyspepsia
  • Tooth problems
  • Headache
  • Nasopharyngitis
  • Abdominal upper pain, diarrhea

More serious side effects of Nasacort include:

  • Nasal septal perforation
  • Candida albicans infection
  • Impaired wound healing
  • Glaucoma or posterior subcapsular cataracts
  • Potential worsening of tuberculosis, fungal, bacterial, viral, or parasitic infections, or ocular herpes simplex
  • Hypercorticism and suppression of the immune system
  • Potential reduction in growth velocity in children

The most common side effects of Flonase in clinical trials include:

  • Sore throat
  • Nose bleeds
  • Nasal burning/nasal irritation
  • Nausea, vomiting
  • Asthma symptoms
  • Cough

More serious side effects of Flonase include

  • Nasal septal perforation
  • Candida albicans infection
  • Impaired wound healing
  • Glaucoma or posterior subcapsular cataracts
  • Hypersensitivity reactions
  • Potential worsening of tuberculosis, fungal, bacterial, viral, or parasitic infections, or ocular herpes simplex
  • Hypercorticism and suppression of the immune system
  • Potential reduction in growth velocity in children

These aren’t all the side effects Nasacort or Flonase can cause. You can find more details in the patient leaflet that comes with your medication. If you have any concerns about side effects, talk to your physician or pharmacist.

Nasacort and Flonase drug interactions

Nasacort can interact with other medications. These include:

  • Antifungal medicine – ketoconazole, miconazole, voriconazole
  • Antiviral medicine – ritonavir, nelfinavir, indinavir

Flonase can interact with other medications. These include:

  • Antifungal medicine – ketoconazole, miconazole, voriconazole
  • Antiviral medicine – ritonavir, nelfinavir, indinavir

Nasacort and Flonase can interact with other medications. This can change how Nasacort and Flonase and other medicines work and can make side effects more likely. Tell your prescribing physician about all your drugs, including over-the-counter (OTC), oral antihistamines (Claritin, Allegra), decongestants, vitamins, and dietary supplements.

Nasacort and Flonase contraindications

You should not use Nasacort if you:

  • Are allergic to the active ingredient triamcinolone acetonide
  • Have had an allergic reaction to any of the other ingredients in Nasacort

Talk to your doctor before using Nasacort if you:

  • Are taking any of the medications that could interact with Nasacort
  • Have an eye infection
  • Have glaucoma or cataracts
  • Have had recent nasal septal ulcers, nasal surgery, or trauma
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

You should not use Flonase if you:

  • Are allergic to the active ingredient fluticasone propionate
  • Have had an allergic reaction to any of the other ingredients in Flonase

Talk to your doctor before using Flonase if you:

  • Are taking any of the medications that could interact with Flonase
  • Have hepatic impairment
  • Have had recent nasal septal ulcers, nasal surgery, or trauma
  • Have glaucoma or cataracts
  • Have diabetes
  • Have a weak immune system or any type of infection
  • Are breastfeeding or are planning to breastfeed
  • Are pregnant or are planning to become pregnant

If you have any concerns about Nasacort or Flonase side effects, talk to your physician, or pharmacist for medical advice. Also inform your healthcare provider about any medical conditions, supplements, and over-the-counter meds you are taking. You are also encouraged to report side effects to the FDA: visit http://www.fda.gov/medwatch or call 1-800-FDA-1088.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.