Abstral Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx an Abstral coupon provider?

NiceRx is a service provider that helps eligible individuals access the Abstral patient assistance program. We do not offer trial offers or free Abstral samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Abstral coupons, discount cards, or Abstral copay cards.

Abstral patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

Can NiceRx help me get Abstral cheaper if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Abstral medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Abstral cost without insurance?

Abstral prices without insurance will vary depending on how much you buy. Prices will also vary by retailer.

How much does Abstral cost with insurance?

The copay for Abstral will vary by the terms of your healthcare plan. To find out what you might need to pay for Abstral with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Abstral?

Abstral (fentanyl sublingual tablets) is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Recipharm AB. Abstral is an opioid agonist used for the management of breakthrough pain in cancer patients 18 years of age and older who are already taking and who are tolerant to around-the-clock opioid therapy for their cancer pain.

Patients considered opioid tolerant are those who are taking, for one week or longer, around-the-clock medicine consisting of at least:

  • 60 mg of oral morphine each day
  • 25 mcg per hour of transdermal fentanyl
  • 30 mg of oral oxycodone each day
  • 8 mg of oral hydromorphone each day
  • 25 mg oral oxymorphone each day
  • 60 mg oral hydrocodone each day
  • or an equianalgesic dose of another opioid daily for a week or longer

Abstral is not for use in opioid non-tolerant patients.

What doses of Abstral are available?

Abstral is available as sublingual tablets, in the following doses: 100 mcg, 200 mcg, 300 mcg, 400 mcg, 600 mcg, and 800 mcg.

When taking Abstral, do not convert on an mcg per mcg basis from any other oral transmucosal fentanyl product to Abstral. Administer directly under the tongue and allow it to dissolve completely. The initial dose of Abstral 100 mcg is no more than two doses per breakthrough pain episode. Titrate to a dose that is tolerable and gives adequate analgesia. Wait at least 2 hours before treating another episode of breakthrough pain. Record your use of Abstral over a number of episodes of breakthrough cancer pain.

Abstral is only to be used as a supplemental pain medication with pain requiring regular opioids if you have developed tolerance to the opioid medication and require opioid treatment for breakthrough pain episodes. When your opioid therapy is no longer required, discontinue a gradual downward of other opioids to minimize possible withdrawal symptoms.

Abstral is available only through a restricted program called the TIRF REMS Access program. See the full prescribing information for the complete boxed warning, and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition. Keep Abstral out of reach of children.

Abstral active ingredients

Abstral contains fentanyl citrate as the active ingredient.

Abstral side effects

The most common side effects of Abstral in clinical trials include:

  • Nausea
  • Somnolence
  • Headache
  • Constipation

In rare instances, Abstral can cause more serious side effects. These can include:

  • Life-threatening respiratory depression in patients with chronic pulmonary disease or in elderly, cachectic, or debilitated patients
  • Serotonin Syndrome
  • Adrenal insufficiency
  • Severe Hypotension (low blood pressure) – monitor during initiation and titration
  • Sedation and respiratory depression in patients with increased intracranial pressure, brain tumors, head injury, or impaired consciousness

Your doctor will assess the benefits of using Abstral against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Abstral to the FDA. Visit, or call 1-800-FDA-1088.

Abstral drug interactions

Abstral can interact with other medications. These include:

  • Mixed agonist/antagonist and partial agonist opioid analgesics – may reduce the analgesic effect of Abstral or precipitate withdrawal symptoms
  • CYP3A4 inhibitors – ritonavir, clarithromycin, itraconazole, ketoconazole, nefazodone, telithromycin, aprepitant, fluconazole, grapefruit juice, verapamil, or cimetidine
  • CYP3A4 inducers – carbamazepine, efavirenz, modafinil, nevirapine, oxcarbazepine, phenytoin, pioglitazone, rifabutin, St. John’s wort, or troglitazone
  • Other central nervous system (CNS) depressants may result in profound sedation, respiratory depression, coma, and death

This list is not exhaustive and other prescription drugs may interact with Abstral.

Abstral contraindications

You should not use Abstral if you:

  • Are allergic to the active ingredient fentanyl citrate
  • Are allergic to any of the other ingredients in Abstral
  • Are an opioid non-tolerant patient
  • Have acute or severe bronchial asthma and are in an unmonitored setting or in the absence of resuscitative equipment
  • Have a known or suspected gastrointestinal obstruction, including paralytic ileus
  • Are pregnant or are planning to become pregnant – prolonged use during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor about your medical condition before using Abstral if you:

  • Are taking any of the medications that could interact with Abstral
  • Have renal or hepatic impairment

Abstral generic

Abstral is the trademark brand name for fentanyl citrate manufactured by Recipharm AB. A generic version of fentanyl citrate is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Abstral savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.