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Amondys 45 Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx an Amondys 45 coupon provider?

NiceRx is not an Amondys 45 coupon, Amondys 45 discount card, or Amondys 45 copay card provider. We do not offer Amondys 45 manufacturer coupons, Amondys 45 discounts, rebates, Amondys 45 savings cards, trial offers, or free Amondys 45 samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Amondys 45 patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

Can NiceRx help me get Amondys 45 cheaper if I have insurance?

How much does Amondys 45 cost without insurance?

Without insurance, Amondys 45 costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Amondys 45 intravenous solution (100 mg/2 mL) will cost around $1,700 for 2 milliliters.

How much does Amondys 45 cost with insurance?

The copay for Amondys 45 will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Amondys 45?

Amondys 45 is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Sarepta Therapeutics, Inc. It is used for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is receptive to exon 45 skipping. FDA approval of Amondys is under accelerated approval based on an increase in dystrophin production in skeletal muscle seen in patients treated with Amondys 45. Continued approval for this use may depend upon verification of a clinical benefit in confirmatory trials.

Duchenne is caused by a genetic mutation, or a change, in the dystrophin gene, where one or multiple exons are missing. This causes errors in the production of dystrophin protein, protein muscles need to function correctly.

Amondys 45 is an exon-skipping therapy. The goal of exon skipping is to allow the body to make a shorter form of the dystrophin protein. Amondys 45 is the third Sarepta RNA exon-skipping therapy for DMD patients that the FDA has approved. The other two are Exondys 51 (eteplirsen), for patients receptive to exon 51 skipping, and Vyondys 53 (golodirsen), for those with mutations receptive to skipping exon 53.

What doses of Amondys 45 are available?

Amondys 45 is available in injection form, in the following doses: 100 mg/2 mL in a single-dose vial.

Serum cystatin C, urine dipstick, and urine protein-to-creatinine ratio should be measured before starting treatment. The recommended dose is 30 milligrams per kilogram of body weight once weekly as an intravenous infusion over 35 to 60 minutes via an in-line 0.2-micron filter.

Please read the prescribing information and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Amondys 45 active ingredients

The active ingredient of Amondys 45 is casimersen, an antisense oligonucleotide of the phosphorodiamidate morpholino oligomer (PMO) subclass.

Amondys 45 side effects

The most common side effects of Amondys 45 in clinical trials compared to placebo include:

  • Upper respiratory tract infection
  • Cough
  • Pyrexia
  • Headache
  • Arthralgia
  • Oropharyngeal pain

In rare instances, Amondys 45 can cause more serious side effects. These can include:

  • Kidney toxicity

Your doctor will assess the benefits of using Amondys 45 against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Amondys 45 to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Amondys 45 drug interactions

Other drugs may interact with Amondys 45, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medications including any supplements you are taking.

Amondys 45 contraindications

You should not use Amondys 45 if you:

  • Are allergic to the active ingredient casimersen
  • Are allergic to any of the other ingredients in Amondys 45
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Amondys 45 if you:

  • Are taking any of the medications that could interact with Amondys 45
  • Are breastfeeding or are planning to breastfeed

Amondys 45 generic

Amondys 45 is the trademark brand name for casimersen manufactured by Sarepta Therapeutics, Inc. Cambridge. A generic version of casimersen is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Amondys 45 savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.