Aptivus Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Aptivus cost savings if eligible

If you are eligible to receive your Aptivus prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Aptivus patient assistance?

To be eligible for the Aptivus patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Aptivus enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Aptivus patient assistance program?

Applying for the Aptivus patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Aptivus, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Aptivus assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Aptivus patient assistance program, we will also request your Aptivus medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx an Aptivus coupon provider?

NiceRx does not provide Aptivus coupons, discount cards or copay cards. We do not offer printable Aptivus manufacturer coupons, Aptivus discounts, rebates, Aptivus savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Aptivus medication with NiceRx.

Can NiceRx help me get Aptivus cheaper if I have insurance?

NiceRx may be able to help you access Aptivus patient assistance if:

  • You have a high copay or coinsurance responsibility for Aptivus
  • Your insurance company will not pay for your Aptivus prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Aptivus cost without insurance?

Aptivus prices without insurance will vary by retailer. As a guide, Aptivus oral capsules 250 mg will typically cost around $2000 for 120 capsules.

How much does Aptivus cost with insurance?

Your individual healthcare plan will determine the copay of Aptivus with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Aptivus?

Aptivus is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Boehringer Ingelheim Limited. It is an antiviral medicine that prevents the human immunodeficiency virus (HIV) from multiplying in your body.

Aptivus, a protease inhibitor, co-administered with ritonavir, is indicated for combination antiretroviral treatment of HIV-1 infected patients who are treatment-experienced and infected with HIV-1 strains resistant to more than one protease inhibitor.

What doses of Aptivus are available?

Aptivus is available in capsule form, in the following doses: 250 mg, and oral solution form, in the following doses: 100 mg/mL.

For adults administer 500 mg Aptivus with 200 mg ritonavir, twice daily. For pediatric patients (age 2 to 18 years) the dose is based on body weight or body surface area.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Aptivus active ingredients

Aptivus contains tipranavir as the active ingredient.

Aptivus side effects

The most common side effects of Aptivus in clinical trials include:

  • Diarrhea
  • Nausea, vomiting
  • Pyrexia
  • Stomach pain
  • Fatigue
  • Headache
  • Rash – more frequent in pediatric patients than in adults

In rare instances, Aptivus can cause more serious adverse effects. These can include:

  • Immune system disorders
  • Hepatic Impairment
  • Intracranial hemorrhage, platelet aggregation, and coagulation
  • New onset or exacerbations of diabetes mellitus, hyperglycemia, immune reconstitution syndrome, redistribution/accumulation of body fat, and elevated lipids. Monitor cholesterol and triglycerides prior to therapy and periodically thereafter
  • Hemophilia – spontaneous bleeding may occur, and additional factor VIII may be required

Your doctor will assess the benefits of using Aptivus against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Aptivus to the FDA. Visit, or call 1-800-FDA-1088.

Aptivus drug interactions

Aptivus can interact with other medications. These include:

  • Antiplatelet drugs – clopidogrel
  • Blood thinners – warfarin, heparins
  • NSAIDs – ibuprofen, naproxen, sulindac, indomethacin
  • Estrogens – ethinyl estradiol
  • Garlic supplements
  • Vitamin E
  • Macrolide antibiotics – erythromycin, rifampin
  • St. John’s wort
  • Drugs used to treat seizures – carbamazepine, phenytoin
  • Alfuzosin
  • Benzodiazepines – midazolam, triazolam
  • Heart rhythm drugs – amiodarone, bepridil, flecainide, propafenone, quinidine
  • Colchicine
  • Ergot-containing drugs – ergotamine, ergonovine, methylergonovine
  • Other HIV medications – etravirine
  • Other protease inhibitors – fosamprenavir, lopinavir, saquinavir
  • Pimozide
  • Statin cholesterol drugs – atorvastatin, lovastatin, simvastatin
  • Drugs to treat erectile dysfunction-ED or pulmonary hypertension – sildenafil, vardenafil
  • Cisapride by affecting hepatic/intestinal enzyme CYP3A4 metabolism
  • Hormonal birth control pills, patches, or rings

This list is not exhaustive and other prescription drugs may interact with Aptivus.

Aptivus contraindications

You should not use Aptivus if you:

  • Are allergic to the active ingredient tipranavir or to sulfa drugs
  • Are allergic to any of the other ingredients in Aptivus
  • Have moderate or severe (Child-Pugh Class B or C) hepatic impairment
  • Are under 2 years of age
  • Are pregnant or are planning to become pregnant

Talk to your doctor about your medical condition before using Aptivus if you:

  • Are taking any of the medications that could interact with Aptivus
  • Have liver disease (especially hepatitis B or C)
  • Have diabetes
  • Have high cholesterol or triglycerides
  • Have a bleeding disorder such as hemophilia
  • Are breastfeeding or are planning to breastfeed

Aptivus generic

Aptivus is the trademark brand name for tipranavir manufactured by Boehringer Ingelheim Limited. A generic version of tipranavir is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Aptivus savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.