BeneFix Coupon & Prices

Is your BeneFix medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your BeneFix medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Your monthly BeneFix cost savings if eligible

If you are eligible to receive your BeneFix prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for BeneFix patient assistance?

To be eligible for the BeneFix patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each BeneFix enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Benefix patient assistance program?

Applying for the BeneFix patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as BeneFix, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for BeneFix assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the BeneFix patient assistance program, we will also request your BeneFix medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx a BeneFix coupons provider?

NiceRx does not provide BeneFix coupons, discount cards or copay cards. We do not offer printable BeneFix manufacturer coupons, BeneFix discounts, rebates, BeneFix savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your BeneFix medication with NiceRx.

Can NiceRx help me get BeneFix if I have insurance?

NiceRx may be able to help you access BeneFix patient assistance if:

  • You have a high copay or coinsurance responsibility for BeneFix
  • Your insurance company will not pay for your BeneFix prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does BeneFix cost without insurance?

BeneFix prices without insurance will vary by retailer. As a guide, BeneFix 500 IU will typically cost around $1.45 for 1 IU.

How much does BeneFix cost with insurance?

Your individual healthcare plan will determine the copay of BeneFix with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is BeneFix?

BeneFix is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Pfizer Inc. It is a recombinant human blood coagulation factor IX that temporarily replaces the missing clotting factor IX that is needed for effective hemostasis. It is indicated for the treatment of:

  • Adults and children with hemophilia B (congenital factor IX deficiency or Christmas disease) for; On-demand treatment and control of bleeding episodes, or Perioperative management of bleeding
  • Patients 16 years of age and older with hemophilia B (congenital factor IX deficiency or Christmas disease) for; Routine prophylaxis to reduce the frequency of bleeding episodes

BeneFix is not indicated for induction of immune tolerance in patients with hemophilia B, or for the treatment of hemophilia A.

What doses of BeneFix are available?

BeneFix is available as a lyophilized powder in single-use vials, in the following doses: nominally 250, 500, 1000, 2000, or 3000 IU.

Please read the full prescribing information and the product information and always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

BeneFix active ingredients

BeneFix contains coagulation factor IX (recombinant) as the active ingredient.

BeneFix side effects

The most common side effects of BeneFix in clinical trials include:

  • Fever, cough, nausea
  • Injection site reaction
  • Injection site pain
  • Headache, dizziness, and rash

In rare instances, BeneFix can cause more serious adverse events. These can include:

  • Hypersensitivity reactions, including anaphylaxis
  • Thromboembolic complications (abnormal blood clots) including in patients receiving continuous infusion through a central venous catheter
  • Nephrotic syndrome
  • Development of neutralizing antibodies (inhibitors) to BeneFix may occur. If expected plasma factor IX activity levels are not reached, or if the patient presents with an allergic reaction, or if bleeding is not controlled with an expected dose, perform an assay that measures factor IX inhibitor concentration

Call your health care provider or get emergency treatment if you have any of the following symptoms: wheezing, problems breathing, chest tightness, lips and gums turning blue, fast heartbeat, facial swelling, faintness, rash, or hives.

Your doctor will assess the benefits of using BeneFix against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of BeneFix to the FDA. Visit, or call 1-800-FDA-1088.

BeneFix drug interactions

Other drugs may interact with BeneFix, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medicines including any supplements you are taking.

BeneFix contraindications

You should not use BeneFix if you:

  • Are allergic to the active ingredient coagulation factor IX (recombinant)
  • Have manifested life-threatening, immediate hypersensitivity reactions, including anaphylaxis, to the product or its components, including hamster protein

Talk to your doctor before using BeneFix if you:

  • Are taking any of the medications that could interact with BeneFix
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

BeneFix generic

BeneFix is the trademark brand name for coagulation factor IX (recombinant) manufactured by Pfizer Inc. A generic version of coagulation factor IX (recombinant) is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find BeneFix savings through NiceRx.

Related conditions

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.