Bevyxxa Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a Bevyxxa coupon provider?

At NiceRx, we help eligible individuals access the Bevyxxa patient assistance program. This means that we are not a Bevyxxa coupon, a Bevyxxa discount card, or a Bevyxxa copay card provider. We do not offer any medication trial offers, or free Bevyxxa samples.

Bevyxxa patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

Can NiceRx help me get Bevyxxa cheaper if I have insurance?

How much does Bevyxxa cost without insurance?

Bevyxxa costs without insurance will vary depending on how much you buy and the retailer you buy it from. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Bevyxxa cost with insurance?

The copay of Bevyxxa will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Bevyxxa?

Bevyxxa is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Portola Pharmaceuticals, Inc. It is used for the prophylaxis of venous thromboembolism (VTE) in adult patients hospitalized for an acute medical illness who are at risk for thromboembolic complications due to moderate or severe restricted mobility and other risk factors for VTE. Bevyxxa is not recommended for use in patients with prosthetic heart valves.

What doses of Bevyxxa are available?

Bevyxxa is available in capsule form, in the following doses: 40 mg and 80 mg.

The recommended dose is an initial single dose of 160 mg, followed by 80 mg once daily, at the same time each day with food. The dose should be reduced for patients with severe renal impairment, or those on P-glycoprotein (P-GP) inhibitors.

Please read the prescribing information and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Bevyxxa active ingredients

Bevyxxa contains betrixaban an extremely potent factor Xa inhibitor. Approval of Bevyxxa is based on results from the Apex study, comparing oral betrixaban with injectable enoxaparin in assessing the prevention of VTE in high-risk patients. Efficacy was measured by a score comprising either the occurrence of asymptomatic proximal DVT (deep vein thrombosis) or symptomatic DVT, non-fatal pulmonary embolism (PE), or VTE-related death. Bevyxxa reduced the incidence of DVT and PE blood clots compared with those taking enoxaparin plus placebo with no significant increase in major bleeding.

Bevyxxa side effects

The most common side effects of Bevyxxa in clinical trials compared to placebo (incidence >5%) include:

  • Bleeding

In rare instances, Bevyxxa can cause more serious side effects. These can include:

  • Increased risk of bleeding – serious, potentially fatal bleeding
  • Severe renal impairment

Your doctor will assess the benefits of using Bevyxxa against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Bevyxxa to the FDA. Visit, or call 1-800-FDA-1088.

Bevyxxa drug interactions

Bevyxxa can interact with other medications. These include:

  • P-GP inhibitors
  • Oral anticoagulants – heparin, warfarin
  • Cyclosporine
  • St. John’s wort
  • Antiviral medicines to treat HIV/AIDS
  • Heart or blood pressure medicine
  • Anticonvulsants
  • NSAIDs (non-steroidal anti-inflammatory drugs)

This list is not exhaustive and other prescription drugs may interact with Bevyxxa.

Bevyxxa contraindications

You should not use Bevyxxa if you:

  • Have a known hypersensitivity to the active ingredient betrixaban
  • Are allergic to any of the other ingredients in Bevyxxa
  • Have active pathological bleeding

Talk to your doctor before using Bevyxxa if you:

  • Are taking any of the medications that could interact with Bevyxxa
  • Have renal impairment (CrCl ≥ 15 to < 30 mL/min)
  • Have hepatic impairment
  • Have a genetic spinal defect
  • Have a spinal catheter in place or if a catheter has been recently removed
  • Have had spinal surgery, repeated spinal taps, or epidural anesthesia
  • Take an NSAID, or use other medicines to treat or prevent blood clots
  • Have liver or kidney disease
  • Have an artificial heart valve
  • Have a bleeding or blood clotting disorder
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Bevyxxa generic

Bevyxxa is the trademark brand name for betrixaban manufactured by Portola Pharmaceuticals, Inc. A generic version of betrixaban is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Bevyxxa savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.