Brukinsa Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Brukinsa cost savings if eligible

If you are eligible for the Brukinsa patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Brukinsa prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Brukinsa patient assistance program?

We will review your application to determine whether you are eligible for the Brukinsa patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Brukinsa patient assistance program?

We make it as easy as possible to apply for the Brukinsa patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Brukinsa. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Brukinsa assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Brukinsa patient assistance program, and we will automatically request your Brukinsa medication refills for up to 1 year.

Is NiceRx a Brukinsa coupons provider?

We are a service provider that helps eligible individuals access the Brukinsa patient assistance program. That means that we do not offer printable Brukinsa manufacturer coupons, Brukinsa discounts, or free Brukinsa samples. We are not a Brukinsa coupon provider or Brukinsa discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Brukinsa if I have insurance?

We may be able to help you to access Brukinsa patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Brukinsa medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Brukinsa cost without insurance?

Brukinsa’s cost without insurance will vary depending on where you buy it. As a guide, Brukinsa oral capsules 80 mg usually cost $14,100 for 120 capsules. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Brukinsa cost with insurance?

The copay for Brukinsa with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Brukinsa?

Brukinsa is a Bruton’s tyrosine kinase inhibitor, manufactured by BeiGene, Ltd. It has FDA approval (U.S. Food and Drug Administration) for the treatment of:

  • Adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. This indication is approved under accelerated approval based on the overall response rate
  • Waldenström’s Macroglobulinemia – This approval is based on Phase 3 Aspen trial comparing Brukinsa against ibrutinib  
  • Relapsed or refractory marginal zone lymphoma (MZL) – The FDA approval is based on efficacy results from two single-arm clinical trials, with overall response rate as assessed by the independent review committee (IRC) per 2014 Lugano Classification as the primary endpoint

What doses of Brukinsa are available?

Brukinsa is available in capsule form, in the following doses: 80 mg.

The recommended dose is 160 mg orally twice daily or 320 mg orally once daily. Capsules should be swallowed whole with water, with or without food. Patients with severe hepatic impairment should have a reduced dose. Patients are advised not to open, break, or chew the capsules. Toxicity should be managed using treatment interruption, dose reduction, or discontinuation.

Please see the full prescribing information including patient information, and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Brukinsa active ingredients

The active ingredient zanubrutinib is a small-molecule BTK inhibitor. In nonclinical studies, zanubrutinib reduced tumor growth.

Brukinsa side effects

The most common adverse reactions of Brukinsa in clinical trials include:

  • Neutropenia – decreased neutrophil count
  • Thrombocytopenia – decreased platelet count
  • Upper respiratory tract infection, cough
  • Decreased white blood cell count
  • Anemia
  • Decreased hemoglobin
  • Rash, bruising
  • Diarrhea
  • Musculoskeletal pain

In rare instances, Brukinsa can cause more serious side effects. These can include:

  • Hemorrhage
  • Infections
  • Cytopenias
  • Second Primary Malignancies – other malignancies have occurred in patients including skin cancers. Patients are advised to use sun protection
  • Cardiac Arrhythmias

Your healthcare professional will assess the benefits of using Brukinsa against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Brukinsa to the FDA. Visit, or call 1-800-FDA-1088.

Brukinsa drug interactions

Brukinsa can interact with other medications. These include:

  • CYP3A Inhibitors
  • CYP3A Inducers

This list is not exhaustive and other prescription drugs may interact with Brukinsa.

Brukinsa contraindications

You should not use Brukinsa if you:

  • Are allergic to the active ingredient zanubrutinib
  • Are allergic to any of the other ingredients in Brukinsa
  • Are pregnant or are planning to become pregnant – Embryo-Fetal Toxicity. Can cause fetal harm. Women are advised to avoid during pregnancy and to use effective birth control (contraception) during treatment and for at least 1 week after the last dose
  • Are breastfeeding or are planning to breastfeed – Do not breastfeed during treatment with Brukinsa and for at least 2 weeks after your last dose

Talk to your doctor before using Brukinsa if you:

  • Are taking any of the medications that could interact with Brukinsa
  • Have bleeding problems.
  • Have had recent surgery or plan to have surgery
  • Have an infection
  • Have or had heart rhythm problems
  • Have high blood pressure
  • Have liver problems, including hepatitis B virus (HBV) infection

Brukinsa generic

Brukinsa is the trademark brand name for zanubrutinib manufactured by BeiGene, Ltd. A generic version of zanubrutinib is OR is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Brukinsa savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.