Bylvay Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Bylvay cost savings if eligible

With our assistance, you could access the Bylvay patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Bylvay patient assistance?

We review each Bylvay enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Bylvay patient assistance program?

Our process makes it as easy as possible to apply for the Bylvay patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Bylvay, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Bylvay coupon provider?

NiceRx is not a Bylvay coupon, Bylvay discount card, or Bylvay copay card provider. We do not offer Bylvay manufacturer coupons, Bylvay discounts, rebates, Bylvay savings cards, trial offers, or free Bylvay samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me get Bylvay cheaper if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Bylvay
  • Your insurance company will not pay for your Bylvay prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Bylvay cost without insurance?

Without insurance, Bylvay costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Bylvay capsule 400 mcg will cost around $13,900 for 30 capsules.

How much does Bylvay cost with insurance?

The copay for Bylvay will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Bylvay?

Bylvay is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Albireo Pharma, Inc. Bylvay is an ileal bile acid transporter inhibitor (IBAT inhibitor) used for the treatment of pruritus in patients 3 months of age and older with progressive familial intrahepatic cholestasis (PFIC).

PFIC is a rare hereditary liver disease in which liver cells cannot produce and secrete bile properly, causing a build-up of bile in the liver cells. This is called cholestasis. Cholestasis damages the liver, causing cirrhosis and liver failure within the first ten years of life. There are three known types of PFIC: PFIC type 1, PFIC type 2, and PFIC type 3. Bylvay may not be effective in PFIC type 2 patients with ABCB11 variants resulting in a non-functional or complete absence of bile salt export pump protein (BSEP-3).

The odevixibat also holds orphan drug designations for the treatment of Alagille Syndrome, biliary atresia, and primary biliary cholangitis.

What doses of Bylvay are available?

Bylvay is available in oral pellet form, in the following doses: 200 mcg, and 600 mcg, and in capsule form in the following doses: 400 mcg, and 1200 mcg.

This medication comes in 2 dosage forms, a capsule to swallow or a capsule that contains pellets to sprinkle on soft food. The recommended dosage is 40 mcg/kg once daily in the morning with a meal. If there is no improvement in pruritus after 3 months, your dosage may be increased up to 120 mcg/kg once daily. The maximum daily dose is 6 mg.

If you are taking bile acid-binding resins such as cholestyramine, colesevelam, or colestipol, take Bylvay at least 4 hours before or at least 4 hours after taking these other medications.

Please see the full prescribing information and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Bylvay active ingredients

The active ingredient of Bylvay is odevixibat. Although the complete mechanism by which odevixibat improves pruritus in PFIC patients is not fully understood, it may involve inhibition of the IBAT, resulting in decreased reuptake of bile salts, as seen by a decrease in serum bile acids.

Bylvay side effects

The most common side effects of Bylvay in clinical trials compared to placebo include:

  • Liver test abnormalities – obtain baseline liver tests and monitor during treatment
  • Diarrhea, abdominal pain, vomiting
  • Fat-soluble vitamin deficiency – supplement if deficiency is observed. If FSV deficiency persists or worsens despite FSV supplementation, discontinue treatment

Your caregiver will assess the benefits of using Bylvay against your risk of adverse events. Patients are encouraged to report negative side effects or adverse reactions of Bylvay to the FDA. Visit, or call 1-800-FDA-1088.

Bylvay drug interactions

Bylvay can interact with other medications. These include:

  • Bile acid-binding resins – cholestyramine, colesevelam, or colestipol

This list is not exhaustive and other prescription drugs may interact with Bylvay.

Bylvay contraindications

You should not use Bylvay if you:

  • Are allergic to the active ingredient odevixibat
  • Are allergic to any of the other ingredients in Bylvay
  • Are pregnant or are planning to become pregnant – Based on animal data, may cause cardiac malformations

Talk to your doctor before using Bylvay if you:

  • Are taking any of the medications that could interact with Bylvay
  • Are breastfeeding or are planning to breastfeed

Bylvay generic

Bylvay is the trademark brand name for odevixibat manufactured by Albireo Pharma, Inc., Boston. A generic version of odevixibat is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Bylvay savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.