Cerebyx Coupon & Prices

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Is NiceRx a Cerebyx coupon provider?

NiceRx does not provide Cerebyx coupons, discount cards, or copay cards. We do not offer printable Cerebyx manufacturer coupons, Cerebyx discounts, rebates, Cerebyx savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Cerebyx medication with NiceRx.

Can NiceRx help me get Cerebyx cheaper if I have insurance?

How much does Cerebyx cost without insurance?

Cerebyx prices without insurance will vary by retailer. As a guide, Cerebyx injectable solution (100 mgPE/2 mL) will typically cost around $710 for 50 milliliters.

How much does Cerebyx cost with insurance?

Your healthcare plan will determine the copay of Cerebyx with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Cerebyx?

Cerebyx is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Pfizer, Inc. It is used to treat generalized tonic-clonic status epilepticus (epilepsy) and the prevention and treatment of seizures occurring during neurosurgery.

Cerebyx can be substituted, for short-term use, for oral phenytoin, but only when oral phenytoin administration is not possible.

What doses of Cerebyx are available?

Cerebyx is available in injection form, in the following doses: 10 mL single-dose vials, containing 500 mg PE, and 2 mL single-dose vials, containing 100 mg PE.

The dose, concentration, and infusion rate of Cerebyx should be expressed as phenytoin sodium equivalents (PE). The loading dose for Status Epilepticus is 15 to 20 mg PE/kg at a rate of 100 to 150 mg PE/min. The pediatric loading dose is 15 to 20 mg PE/kg at a rate of 2 mg PE/kg/min.

For non-emergent loading and maintenance dosing, the adult loading dose is 10 to 20 mg PE/kg given IV or IM. The pediatric loading dose is 10 to 15 mg PE/kg at a rate of 1 to 2 mg PE/kg/min.

The rate of intravenous Cerebyx administration should not exceed 150 mg phenytoin sodium equivalents (PE) per minute in adults and 2 mg PE/kg/min in pediatric patients because of the cardiovascular risk of severe hypotension and cardiac arrhythmias associated with rapid infusion rates.

Please read the labeling and drug information provided and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Cerebyx active ingredients

Cerebyx contains fosphenytoin sodium an anti-epileptic drug also called an anticonvulsant. Fosphenytoin is a prodrug of phenytoin.

Cerebyx side effects

The most common side effects of Cerebyx in clinical trials (incidence ≥10%) include:

  • Injection-site edema
  • Pruritus
  • Nystagmus
  • Dizziness, drowsiness, somnolence, and ataxia

In rare instances, Cerebyx can cause more serious adverse effects. These can include:

  • Purple glove syndrome – edema, discoloration, and pain distal to the site of injection
  • Worsening of porphyria (a genetic enzyme disorder affecting the skin or nervous system)
  • Withdrawal precipitated seizure
  • Serious dermatologic reactions
  • Drug reaction with eosinophilia and systemic symptoms (DRESS)/multiorgan hypersensitivity
  • Angioedema
  • Hematopoietic complications

Your doctor will assess the benefits of using Cerebyx against your risk of adverse events. Patients are encouraged to report negative side effects or adverse reactions of Cerebyx to the FDA. Visit, or call 1-800-FDA-1088.

Cerebyx drug interactions

Cerebyx can interact with other medications. These include:

  • Azole antifungals – fluconazole, ketoconazole, itraconazole
  • Corticosteroids
  • Estrogens
  • Theophylline
  • Warfarin
  • Certain HIV antivirals – amprenavir, indinavir, saquinavir
  • Anti-epileptic agents – felbamate, topiramate, oxcarbazepine, quetiapine
  • Drugs that may decrease plasma phenytoin concentrations – carbamazepine, nelfinavir, reserpine, and ritonavir

This list is not exhaustive and other prescription drugs may interact with Cerebyx.

Cerebyx contraindications

You should not use Cerebyx if you:

  • Have a known hypersensitivity to its ingredients fosphenytoin sodium, hydantoins
  • Are allergic to any of the other ingredients in Cerebyx
  • Have sinus bradycardia, sino-atrial block, second and third-degree A-V block, and Adams-Stokes syndrome
  • Have a history of prior acute hepatotoxicity due to Cerebyx or phenytoin
  • Are taking delavirdine
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Cerebyx if you:

  • Are taking any of the medications that could interact with Cerebyx
  • Have hepatic or renal impairment
  • Have hypoalbuminemia
  • Have heart disease
  • Have diabetes
  • Have low blood pressure
  • Are breastfeeding or are planning to breastfeed

Cerebyx generic

Cerebyx is the trademark brand name for fosphenytoin sodium manufactured by Pfizer, Inc. A generic version of fosphenytoin sodium is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cerebyx savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.