medicationsCholbam

Cholbam Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Cholbam cost savings if eligible

With our assistance, you could access the Cholbam patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Cholbam patient assistance?

We review each Cholbam enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Cholbam patient assistance program?

Our process makes it as easy as possible to apply for the Cholbam patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Cholbam, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Cholbam coupon provider?

NiceRx is not a Cholbam coupon, Cholbam discount card, or Cholbam copay card provider. We do not offer Cholbam manufacturer coupons, Cholbam discounts, rebates, Cholbam savings cards, trial offers, or free Cholbam samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me get Cholbam cheaper if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Cholbam
  • Your insurance company will not pay for your Cholbam prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Cholbam cost without insurance?

Without insurance, Cholbam costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Cholbam oral capsules 50 mg will cost around $26,000 for 90 capsules.

How much does Cholbam cost with insurance?

The copay for Cholbam will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Cholbam?

Cholbam is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Travere Therapeutics, Inc. Cholbam is a bile acid indicated for:

  • Treatment of bile acid synthesis disorders due to single enzyme defects (SEDs)
  • Adjunctive treatment of peroxisomal disorders (PDs) including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea, or complications from decreased fat-soluble vitamin absorption

The safety and effectiveness of Cholbam on extrahepatic manifestations of bile acid synthesis disorders due to SEDs or PDs including Zellweger spectrum disorders have not been established.

What doses of Cholbam are available?

Cholbam is available in capsule form, in the following doses: 50 mg, 250 mg.

The recommended dosage is 10 to 15 mg/kg once daily or in two divided doses, in pediatric patients and adults. See the prescribing information for weight-based dosing tables.

Monitor AST, ALT, GGT, alkaline phosphatase, bilirubin, and INR every month for the first 3 months, every 3 months for the next 9 months, and every 6 months during the next three years, and annually thereafter.

Administer the lowest dose that effectively maintains liver function and discontinue treatment if the liver function does not improve within 3 months of starting treatment, if complete biliary obstruction develops, or if there are persistent clinical or laboratory indicators of worsening liver function or cholestasis. Continue to monitor liver function and consider restarting a lower dose when parameters return to baseline.

Always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Cholbam active ingredients

The active ingredient of Cholbam is cholic acid a primary bile acid synthesized from cholesterol in the liver.

In bile acid synthesis disorders due to SEDs in the biosynthetic pathway, and in PDs including Zellweger spectrum disorders, deficiency of primary bile acids leads to unregulated accumulation of intermediate bile acids and cholestasis. Bile acids aid fat digestion and absorption by forming mixed micelles, and aid absorption of fat-soluble vitamins in the intestine.

Cholic acid enhances bile flow and provides the physiologic feedback inhibition of bile acid synthesis. The mechanism of action of cholic acid has not been fully established; however, it is known that cholic acid and its conjugates are endogenous ligands of the nuclear receptor, farnesoid X receptor (FXR). FXR regulates enzymes and transporters that are involved in bile acid synthesis and in the enterohepatic circulation to maintain bile acid homeostasis under normal physiologic conditions.

Cholbam side effects

The most common side effects of Cholbam in clinical trials include:

  • Diarrhea
  • Reflux esophagitis
  • Malaise
  • Jaundice
  • Skin lesion
  • Nausea
  • Abdominal pain
  • Intestinal polyp
  • Urinary tract infection
  • Peripheral neuropathy

In rare instances, Cholbam can cause more serious side effects. These can include:

  • Exacerbation of liver impairment

Your doctor will assess the benefits of using Cholbam against your risk of adverse effects. Patients are encouraged to report negative side effects or adverse events of Cholbam to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Cholbam drug interactions

Cholbam can interact with other medications. These include:

  • Bile salt efflux pump (BSEP) inhibitors – cyclosporine
  • Bile acid resins and aluminum-based antacids – take Cholbam at least 1 hour before or 4 to 6 hours after a bile acid-binding resin or aluminum-based antacids

This list is not exhaustive and other prescription drugs may interact with Cholbam. Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Cholbam contraindications

You should not use Cholbam if you:

  • Are allergic to the active ingredient cholic acid
  • Are allergic to any of the other ingredients in Cholbam

Talk to your doctor before using Cholbam if you:

  • Are taking any of the medications that could interact with Cholbam
  • Have liver disease
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Cholbam generic

Cholbam is the trademark brand name for cholic acid manufactured by Travere Therapeutics, Inc. A generic version of cholic acid is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cholbam savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.