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Cinryze Patient assistance program

Is your Cinryze medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Cinryze medication with our help.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Cinryze cost savings if eligible

If you are eligible for the Cinryze patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Cinryze through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Cinryze patient assistance program?

You could receive your Cinryze without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Cinryze patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Cinryze.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Cinryze patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Cinryze medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Cinryze coupons provider?

At NiceRx, we help eligible individuals access the Cinryze patient assistance program. This means that we are not a Cinryze coupon, a Cinryze discount card, or a Cinryze copay card provider. We do not offer any medication trial offers or free Cinryze samples.

Can NiceRx help me get Cinryze if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Cinryze medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Cinryze cost without insurance?

Cinryze costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Cinryze intravenous powder for injection 500 units will typically cost around $2,980 for 1 powder for injection. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Cinryze cost with insurance?

The copay of Cinryze will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Cinryze?

Cinryze is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire plc, part of Takeda Pharmaceuticals. Cinryze is a C1 esterase inhibitor (C1-INH) indicated for routine prophylaxis against angioedema attacks in adults, adolescents, and pediatric patients (6 years of age and older) with Hereditary angioedema (HAE).

Bradykinin is the main cause of HAE symptoms such as swelling attacks and pain. Cinryze increases the amount of C1 esterase inhibitor in your body. This decreases the amount of bradykinin, which helps relieve swelling and pain that occurs with an HAE attack.

What doses of Cinryze are available?

Cinryze is available in lyophilized powder form, in the following doses: Approximately 500 Units (lyophilized) in an 8 mL vial.

Always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Cinryze active ingredients

Cinryze contains C1 esterase inhibitor [human] as the active ingredient.

Cinryze side effects

The most common side effects of Cinryze in clinical trials include:

  • Headache
  • Nausea, vomiting
  • Rash
  • Fever

In rare instances, Cinryze can cause more serious side effects. These can include:

  • Hypersensitivity reactions
  • Serious arterial and venous thromboembolic (TE) events
  • Cinryze is made from human plasma and may contain infectious agents such as viruses and, theoretically, the Creutzfeldt-Jakob disease agent

Get emergency medical help if you have signs of anaphylaxis to Cinryze – hives, chest pain, fast heartbeats, feeling light-headed, problems breathing, blue lips or gums, or swelling of your face, lips, tongue, or throat. Your doctor will assess the benefits of using Cinryze against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Cinryze to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Cinryze drug interactions

There is currently no data for Cinryze interactions with other medications. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Cinryze contraindications

You should not use Cinryze if you:

  • Are allergic to the active ingredient C1 esterase inhibitor [human]
  • Have had a life-threatening allergic reaction to any of the other ingredients in Cinryze
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor about all of your medical conditions before using Cinryze if you:

  • Are taking any of the medications that could interact with Cinryze
  • Have had a stroke or blood clot
  • Have heart problems
  • Have an “in-dwelling” catheter

Cinryze generic

Cinryze is the trademark brand name for C1 esterase inhibitor [human] manufactured by Shire plc, part of Takeda Pharmaceuticals. A generic version of C1 esterase inhibitor [human] is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cinryze savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.