Cortef Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a Cortef coupon provider?

NiceRx does not provide Cortef coupons, discount cards or copay cards. We do not offer printable Cortef manufacturer coupons, Cortef discounts, rebates, Cortef savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs.

Cortef patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

How much does Cortef cost without insurance?

Cortef prices without insurance will vary by retailer. As a guide, Cortef oral tablets 5 mg will typically cost around $60 for 50 tablets.

How much does Cortef cost with insurance?

Your individual healthcare plan will determine the copay of Cortef with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Cortef?

Cortef is an FDA (U.S. Food and Drug Administration) approved medication distributed by Pharmacia & Upjohn Co., Division of Pfizer Inc. Cortef contains hydrocortisone a synthetic (man-made) version of cortisol made naturally in your body by the adrenal gland.

Hydrocortisone is a corticosteroid that works on the immune system. It is used to treat severe allergic reactions, adrenal problems, arthritis, asthma, blood or bone marrow problems, lupus, skin conditions, and ulcerative colitis.

What doses of Cortef are available?

Cortef is available as a hydrocortisone tablet, in the following doses: 5 mg.

Always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Cortef active ingredients

Cortef contains hydrocortisone as the active ingredient.

Cortef side effects

The most common side effects of Cortef in clinical trials include:

  • Problems with vision, burning, dry, or itching eyes
  • Dizziness, headache
  • Irregular heartbeats
  • Mood changes, anxiety
  • Runny or stuffy nose, sneezing, sore throat, trouble breathing
  • Trouble sleeping
  • Weight gain

In rare instances, Cortef can cause more serious adverse effects. These can include:

  • Fluid and electrolyte disturbances – fluid retention, congestive heart failure, potassium loss, hypertension
  • Anemia
  • Muscle weakness
  • Osteoporosis
  • Gastrointestinal disturbances – peptic ulcer with possible perforation, bloating,
  • Pancreatitis
  • An increase in alanine transaminase, aspartate transaminase, alkaline phosphatase
  • Impaired wound healing
  • Cataracts
  • Glaucoma

Your doctor will assess the benefits of using Cortef against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Cortef to the FDA. Visit, or call 1-800-FDA-1088.

Cortef drug interactions

Cortef can interact with other medications. These include:

  • Aldesleukin
  • Mifepristone
  • Other drugs that can cause bleeding/bruising such as clopidogrel
  • NSAIDs – ibuprofen, naproxen
  • Blood thinners – warfarin

This list is not exhaustive and other prescription drugs may interact with Cortef.

Cortef contraindications

You should not use Cortef if you:

  • Are allergic to the active ingredient hydrocortisone
  • Are allergic to any of the other ingredients in Cortef
  • Are pregnant or are planning to become pregnant

Talk to your doctor about your medical condition before using Cortef if you:

  • Are taking any of the medications that could interact with Cortef
  • Have had an immunization with live vaccines
  • Have come into contact with people who have infections such as chickenpox, measles, and flu
  • Have cataracts
  • Have congestive heart failure
  • Have Cushing’s syndrome (adrenal gland problem)
  • Are diabetic
  • Have an eye infection such as herpes
  • Have glaucoma
  • Have hypertension (high blood pressure)
  • Have an underactive thyroid
  • Have cirrhosis of the liver
  • Have Myasthenia gravis (severe muscle weakness)
  • Do not get enough vitamin D or calcium in your diet
  • Have osteoporosis
  • Have an adrenal tumor (pheochromocytoma)
  • Have diverticulitis or ulcerative colitis
  • Have a weak immune system
  • Have a fungal infection
  • Are breastfeeding or are planning to breastfeed – It is unknown if this drug passes into breast milk

Cortef generic

Cortef is the trademark brand name for hydrocortisone distributed by Pharmacia & Upjohn Co., Division of Pfizer Inc. A generic version of hydrocortisone is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cortef savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.