Cosela Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Cosela cost savings if eligible

With our assistance, you could access the Cosela patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Cosela patient assistance?

We review each Cosela enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Cosela patient assistance program?

Our process makes it as easy as possible to apply for the Cosela patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Cosela , your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx a Cosela coupons provider?

NiceRx is not a Cosela coupon, Cosela discount card, or Cosela copay card provider. We do not offer Cosela manufacturer coupons, Cosela discounts, rebates, Cosela savings cards, trial offers, or free Cosela samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Cosela
  • Your insurance company will not pay for your Cosela prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Cosela cost without insurance?

Without insurance, Cosela costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Cosela intravenous powder for injection 300 mg will cost around $1,500 for a supply of 1 powder for injection.

How much does Cosela cost with insurance?

The copay for Cosela will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Cosela?

Cosela is an FDA (U.S. Food and Drug Administration) approved medication manufactured by G1 Therapeutics, Inc. It is a kinase inhibitor used to decrease the incidence of chemotherapy-induced myelosuppression (decreased bone marrow activity) in adult patients when given prior to a platinum/etoposide-containing regimen or topotecan-containing regimen for extensive-stage small cell lung cancer (ES-SCLC).

What doses of Cosela are available?

Cosela is available in injection form, in the following doses: 300 mg of trilaciclib as a lyophilized cake in a single-dose vial.

The recommended dose is 240 mg/m2 as a 30-minute intravenous infusion completed within 4 hours, before the start of chemotherapy on each day of chemotherapy. See the full prescribing information for instructions on administration.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Cosela active ingredients

The active ingredient of Cosela is trilaciclib. It is the first and only FDA-approved treatment to provide myeloprotective efficacy and helps protect against myelosuppression, while chemotherapy targets cancer cells.

Cosela’s approval is based on data from three randomized, placebo-controlled trials that showed patients receiving Cosela prior to the start of chemotherapy had a clinically meaningful and statistically significant reduction in the duration and severity of neutropenia. Results also showed a positive impact on red blood cell transfusions and other myeloprotective measures. The trials evaluated Cosela in combination with carboplatin/etoposide (+/- the immunotherapy atezolizumab) and topotecan chemotherapy regimens.

Cosela side effects

The most common adverse reactions of Cosela in clinical trials compared to placebo include:

  • Fatigue, myositis
  • Hypocalcemia, anemia, hypokalemia, hypophosphatemia
  • Increased aspartate aminotransferase
  • Headache, increased risk of pneumonia
  • Thrombocytopenia (low blood platelets)
  • Cerebrovascular accident
  • Thrombosis, ischemic stroke
  • Infusion-related reaction
  • Respiratory failure

In rare instances, Cosela can cause more serious side effects. These can include:

  • Injection-Site Reactions, including phlebitis and thrombophlebitis
  • Acute drug hypersensitivity reactions
  • Interstitial lung disease (ILD)/Pneumonitis – patients treated with CDK4/6 inhibitors should be monitored for pulmonary symptoms indicative of ILD/pneumonitis

Your doctor will assess the benefits of using Cosela against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Cosela to the FDA. Visit, or call 1-800-FDA-1088.

Cosela drug interactions

Cosela can interact with other medications. These include:

  • OCT2, MATE1, and MATE-2K substrates (dofetilide, dalfampridine, cisplatin) – co-administration of Cosela may increase the concentration or net accumulation of the substrates in the kidney

This list is not exhaustive and other prescription drugs may interact with Cosela.

Cosela contraindications

You should not use Cosela if you:

  • Are allergic to the active ingredient trilaciclib
  • Are allergic to any of the other ingredients in Cosela
  • Are pregnant or are planning to become pregnant – Based on its mechanism of action, Cosela can cause embryo-fetal toxicity when administered to a pregnant woman. Females of reproductive potential should use an effective method of contraception during treatment and for at least 3 weeks after the final dose

Talk to your doctor before using Cosela if you:

  • Are taking any of the medications that could interact with Cosela
  • Are breastfeeding or are planning to breastfeed – do not breastfeed while taking Cosela and for at least 3 weeks after the last dose

Cosela generic

Cosela is the trademark brand name for trilaciclib manufactured by G1 Therapeutics, Inc. A generic version of trilaciclib is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cosela savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.