Cosmegen Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Cosmegen cost savings if eligible

The Cosmegen patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Cosmegen, regardless of the retail price.

Am I eligible for the Cosmegen patient assistance program?

To find out if you are eligible for Cosmegen assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Cosmegen patient assistance program?

Our application process aims to make it as easy as possible to apply for the Cosmegen patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Cosmegen.

NiceRx will review your application and determine whether you may be eligible for Cosmegen assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Cosmegen patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Cosmegen.

Is NiceRx a Cosmegen coupon provider?

NiceRx is a service provider that helps eligible individuals access the Cosmegen patient assistance program. We do not offer trial offers or free Cosmegen samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Cosmegen coupons, discount cards, or Cosmegen copay cards.

Can NiceRx help me get Cosmegen cheaper if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Cosmegen medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Cosmegen cost without insurance?

Cosmegen prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Cosmegen intravenous powder for injection 0.5 mg typically costs $2,600 for 1 powder for injection

How much does Cosmegen cost with insurance?

The copay for Cosmegen will vary by the terms of your healthcare plan. To find out what you might need to pay for Cosmegen with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Cosmegen?

Cosmegen is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Recordati Rare Diseases Inc. Cosmegen is used to treat different types of cancers that affect the kidneys, uterus, testicles, bones, muscles, joints, and soft tissues.

It is classed as an actinomycin for the treatment of :

  • Adult and pediatric patients with Wilms tumor, childhood rhabdomyosarcoma, Ewing sarcoma, or metastatic, nonseminomatous testicular cancer, as part of a multi-phase, combination chemotherapy regimen
  • Post-menarchal patients with gestational trophoblastic neoplasia, as a single agent or as part of a combination chemotherapy regimen
  • Adult patients with locally recurrent or locoregional solid malignancies, as part of palliative or adjunctive regional perfusion

What doses of Cosmegen are available?

Cosmegen is available in injection form, in the following doses: 500 mcg lyophilized powder in a single-dose vial.

Cosmegen is for intravenous use. Your recommended dose of Cosmegen is based on the condition you are being treated for, other medication you may be taking, and your body weight.

Please read the full labeling supplied with your medication and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Cosmegen active ingredients

Cosmegen contains dactinomycin (3 H actinomycin D) as the active ingredient. Cosmegen belongs to a class of drugs called antineoplastics, and antibiotics. It is an antibiotic that is able to kill cancer cells by blocking RNA and DNA, a compound that is essential for all cells to live.

Cosmegen side effects

The most common side effects of Cosmegen in clinical trials include:

  • Infection
  • Hair loss
  • Rash
  • Dysphagia
  • Fatigue, fever
  • Nausea, vomiting
  • Anemia, neutropenia, thrombocytopenia (low platelet count)
  • Mucositis, mouth sores
  • Hepatotoxicity

In rare instances, Cosmegen can cause more serious side effects. These can include:

  • Secondary malignancy or leukemia
  • Veno-occlusive disease
  • Extravasation
  • Myelosuppression – monitor blood cell counts before each cycle
  • Renal toxicity
  • Potentiation of radiation toxicity and radiation recall
  • Embryo-fetal toxicity
  • Myalgia, growth retardation

Your doctor will assess the benefits of using Cosmegen against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Cosmegen to the FDA. Visit, or call 1-800-FDA-1088.

Cosmegen drug interactions

Other drugs may interact with Cosmegen, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medication including any supplements you are taking.

Cosmegen contraindications

You should not use Cosmegen if you:

  • Are allergic to the active ingredient dactinomycin
  • Have hypersensitivity to any of the other ingredients in Cosmegen
  • Are pregnant or are planning to become pregnant – may cause fetal harm when administered to a pregnant woman
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Cosmegen if you:

  • Are taking any of the medications that could interact with Cosmegen
  • Have been given a vaccination with live viral vaccines – not recommended before or during treatment
  • Have hepatic impairment
  • Are having radiation treatment

Cosmegen generic

Cosmegen is the trademark brand name for dactinomycin manufactured by Recordati Rare Diseases Inc. A generic version of dactinomycin is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cosmegen savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.