Cuvrior Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a Cuvrior coupon provider?

We are a service provider that helps eligible individuals access patient assistance programs. That means that we do not offer printable Cuvrior manufacturer coupons, Cuvrior discounts, or free Cuvrior samples. We are not a Cuvrior coupon provider or Cuvrior discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Cuvrior patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

How much does Cuvrior cost without insurance?

Cuvrior cost without insurance will vary depending on where you buy it.

How much does Cuvrior cost with insurance?

The copay for Cuvrior with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Cuvrior?

Cuvrior is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Orphalan SA. FDA approval of Cuvrior was based on the results of the global phase 3 trial, CHELATE.

Cuvrior is a copper chelator agent used for the treatment of adult patients with stable Wilson’s disease who are de-coppered and tolerant to penicillamine. Wilson’s disease is a rare genetic disorder that stops the body from removing copper, causing it to build up in the liver, brain, eyes, and other organs. High copper levels can cause life-threatening organ damage.

Cuvrior removes copper from the body by forming a complex that is excreted through urine. Cuvrior may also prevent copper absorption from the intestinal tract.

What doses of Cuvrior are available?

Cuvrior is available in tablet form, in the following doses: 300 mg.

Determine serum non-ceruloplasmin copper (NCC) levels when starting treatment, after 3 months, and then every 6 months thereafter. The starting total daily dosage in adults is 300 mg up to a maximum dosage of 3,000 mg orally in divided doses, twice a day. Take Cuvrior on an empty stomach. Swallow the tablets whole, without crushing, chewing, or dissolving them.

Please see the full prescribing information. Also, read the labeling provided and drug information with your medicine and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Cuvrior active ingredients

Cuvrior contains trientine tetrahydrochloride as the active ingredient.

Cuvrior side effects

The most common side effects of Cuvrior in clinical trials include:

  • Abdominal pain
  • Change of bowel habits
  • Rash
  • Alopecia
  • Mood swings

In rare instances, Cuvrior can cause more serious side effects. These can include:

  • Worsening of symptoms at the initiation of treatment
  • Copper deficiency
  • Iron deficiency
  • Hypersensitivity reactions

Your doctor will assess the benefits of using Cuvrior against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Cuvrior to the FDA. Visit, or call 1-800-FDA-1088.

Cuvrior drug interactions

Cuvrior can interact with other medications. These include:

  • Mineral Supplements such as iron, zinc, calcium, or magnesium

This list is not exhaustive and other prescription drugs may interact with Cuvrior.

Cuvrior contraindications

You should not use Cuvrior if you:

  • Are allergic to the active ingredient trientine tetrahydrochloride
  • Are allergic to any of the other ingredients in Cuvrior
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Cuvrior if you:

  • Are taking any of the medications that could interact with Cuvrior
  • Are breastfeeding or are planning to breastfeed

Cuvrior generic

Cuvrior is the trademark brand name for trientine tetrahydrochloride manufactured by Orphalan SA. A generic version of trientine tetrahydrochloride is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cuvrior savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.