Cystadane Coupon & Prices

Is your Cystadane medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Cystadane medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: Your medication is delivered straight to your door
  • NiceRx Benefit
    Ongoing refills: Your medication is refilled automatically
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Cystadane cost savings if eligible

If you are eligible for the Cystadane patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Cystadane prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Cystadane patient assistance program?

We will review your application to determine whether you are eligible for the Cystadane patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Cystadane patient assistance program?

We make it as easy as possible to apply for the Cystadane patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Cystadane. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Cystadane assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Cystadane patient assistance program, and we will automatically request your Cystadane medication refills for up to 1 year.

Is NiceRx a Cystadane coupon provider?

We are a service provider that helps eligible individuals access the Cystadane patient assistance program. That means that we do not offer printable Cystadane manufacturer coupons, Cystadane discounts, or free Cystadane samples. We are not a Cystadane coupon provider or Cystadane discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Cystadane cheaper if I have insurance?

We may be able to help you to access Cystadane patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Cystadane medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Cystadane cost without insurance?

Cystadane cost without insurance will vary depending on where you buy it. As a guide, Cystadane oral powder for reconstitution 100% usually costs $1,900 for 180 grams. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Cystadane cost with insurance?

The copay for Cystadane with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Cystadane?

Cystadane (betaine anhydrous for oral solution) is an FDA (U.S. Food and Drug Administration) approved medication distributed by Recordati Rare Diseases Inc. Cystadane is a methylating agent indicated for the treatment of homocystinuria to decrease elevated homocysteine blood levels. Included within the category of homocystinuria are cystathionine beta-synthase (CBS) deficiency, 5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency, and cobalamin cofactor metabolism (CBL) defect.

What doses of Cystadane are available?

Cystadane is available in bottles containing 180 grams of betaine anhydrous.

The usual dose in adult and pediatric patients is 6 grams per day, administered orally in divided doses of 3 grams two times a day. In children less than 3 years of age, dosing is started at 100 mg/kg/day, divided into twice-daily doses, and then increased weekly by 50 mg/kg. Monitor patient response by plasma homocysteine levels.

The prescribed amount of Cystadane should be measured with the measuring scoop provided and then dissolved in 4 to 6 ounces of water, juice, milk, or formula, or mixed with food for immediate ingestion. Store Cystadane at room temperature, 15 to 30 °C (59 to 86 °F), and protect from moisture.

Read the full prescribing information and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Cystadane active ingredients

Cystadane contains betaine anhydrous as the active ingredient.

Cystadane side effects

The most common side effects of Cystadane in clinical trials include:

  • Nausea, diarrhea, stomach discomfort, vomiting based on physician survey
  • Anorexia
  • Agitation, depression, irritability, personality disorder
  • Sleep disturbed
  • Dental disorders
  • Hair loss
  • Hives, skin odor abnormalities
  • Urinary incontinence

In rare instances, Cystadane can cause more serious side effects. These can include:

  • Hypermethioninemia – Cystadane may worsen elevated plasma methionine concentrations in patients with CBS deficiency. Keep plasma methionine concentrations below 1,000 μmol/L through dietary medication and, if necessary, a reduction of Cystadane dose

Your doctor will assess the benefits of using Cystadane against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Cystadane to the FDA. Visit, or call 1-800-FDA-1088.

Cystadane  drug interactions

Other drugs may interact with Cystadane, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medicines including any supplements you are taking.

Cystadane contraindications

You should not use Cystadane if you:

  • Are allergic to the active ingredient betaine anhydrous
  • Are allergic to any of the other ingredients in Cystadane
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Cystadane if you:

  • Are taking any of the medications that could interact with Cystadane
  • Are younger than 3 years of age (may benefit from dose titration)
  • Are breastfeeding or are planning to breastfeed

Cystadane generic

Cystadane is the trademark brand name for betaine anhydrous distributed by Recordati Rare Diseases Inc. A generic version of betaine anhydrous is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cystadane savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.

DISCLAIMER: NiceRx is a conduit between consumers in need of prescription drug savings. NiceRx is not affiliated or contracted with any of the pharmaceutical companies or products which are illustrated on this website. NiceRx is not compensated in any capacity by any of the manufacturers. All of the information about prescription drugs on this website has not been provided to NiceRx by the manufacturer.