Cytoxan Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Cytoxan cost savings if eligible

If you are eligible to receive your Cytoxan prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Cytoxan patient assistance?

To be eligible for the Cytoxan patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Cytoxan enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Cytoxan patient assistance program?

Applying for the Cytoxan patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Cytoxan, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Cytoxan assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Cytoxan patient assistance program, we will also request your Cytoxan medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx a Cytoxan coupons provider?

NiceRx does not provide Cytoxan coupons, discount cards, or copay cards. We do not offer printable Cytoxan manufacturer coupons, Cytoxan discounts, rebates, Cytoxan savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Cytoxan medication with NiceRx.

Can NiceRx help me get Cytoxan if I have insurance?

NiceRx may be able to help you access Cytoxan patient assistance if:

  • You have a high copay or coinsurance responsibility for Cytoxan
  • Your insurance company will not pay for your Cytoxan prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Cytoxan cost without insurance?

Cytoxan prices without insurance will vary by retailer. As a guide, Cytoxan oral tablets will typically cost around $150 for 200 tablets.

How much does Cytoxan cost with insurance?

Your individual healthcare plan will determine the copay of Cytoxan with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Cytoxan?

Cytoxan is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Amneal Pharmaceuticals, Inc.

Cyclophosphamide is indicated for the treatment of:

  • Different types of cancer – malignant lymphomas, Hodgkin’s disease, lymphocytic lymphoma, mixed-cell type lymphoma, histiocytic lymphoma, Burkitt’s lymphoma, multiple myeloma, leukemias, mycosis fungoides, neuroblastoma, adenocarcinoma of the ovary, retinoblastoma, breast cancer
  • Minimal change nephrotic syndrome in pediatric patients – biopsy-proven minimal change nephrotic syndrome patients who failed to adequately respond to or are unable to tolerate adrenocorticosteroid therapy

The safety and effectiveness for the treatment of nephrotic syndrome in adults or other renal diseases have not been established.

What doses of Cytoxan are available?

Cytoxan is available in injection, lyophilized powder form, in the following doses: 500 mg, 1 g, and 2 g, and in tablet form, in the following doses: 25 mg and 50 mg.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Cytoxan active ingredients

Cyclophosphamide is an anti-cancer (cytotoxic) chemotherapy drug classed as an alkylating agent.

Cytoxan side effects

The most common side effects of cyclophosphamide in clinical trials include:

  • Nausea, vomiting
  • Loss of appetite
  • Stomach ache
  • Diarrhea
  • Darkening of the skin or nails
  • Neutropenia, febrile neutropenia, fever
  • Alopecia (hair loss)
  • Low blood cell counts – your white blood cells and red blood cells and platelets may temporarily decrease. This can put you at an increased risk of infection, anemia, and bleeding

In rare instances, Cytoxan can cause more serious adverse effects. These can include:

  • Myelosuppression, immunosuppression, bone marrow failure
  • Urinary tract and renal toxicity – hemorrhagic cystitis, pyelitis, ureteritis, and hematuria
  • Cardiotoxicity – myocarditis, myopericarditis, pericardial effusion, arrhythmias, and congestive heart failure
  • Pulmonary toxicity – pneumonitis, pulmonary fibrosis, and pulmonary venous-occlusive disease leading to respiratory failure
  • Secondary malignancies
  • Veno-occlusive liver disease
  • Kidney or bladder problems, mouth sores, joint pain, stopping of menstrual periods, existing wounds that are slow healing, black or bloody stools, severe stomach pain, yellowing eyes or skin, dark urine, mood changes, muscle weakness/spasm
  • Children may be more sensitive to the side effects of this drug, especially possible infertility later in life

This medication may cause very serious effects on your heart, especially when used in high doses, or in combination with radiation treatment or certain other chemotherapy drugs (such as doxorubicin). Seek medical help right away if you develop chest pain, jaw or left arm pain, problems breathing, irregular heartbeat, or symptoms of heart failure (such as shortness of breath, swelling of your ankles or feet, unusual tiredness, or sudden weight gain).

Your doctor will assess the benefits of using Cytoxan against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Cytoxan to the FDA. Visit, or call 1-800-FDA-1088.

Cytoxan drug interactions

Cytoxan can interact with other medications. These include:

  • Allopurinol
  • Chloramphenicol
  • Chloroquine
  • Digoxin
  • Phenobarbital
  • Phenothiazine
  • Primidone
  • St John’s wort
  • Turmeric (curcumin)
  • Voclosporin
  • Tamoxifen may increase the risk of thromboembolic complications.

This list is not exhaustive and other prescription drugs may interact with Cytoxan. Tell your doctor and pharmacist what other prescription drugs and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking.

Cytoxan contraindications

You should not use Cytoxan if you:

  • Are allergic to the active ingredient cyclophosphamide
  • Are allergic to any of the other ingredients in Cytoxan
  • Have urinary outflow obstruction
  • Are pregnant or are planning to become pregnant – women should use a reliable form of birth control while using this medication and for 1 year after stopping treatment
  • Are breastfeeding or are planning to breastfeed – this drug passes into breast milk and may harm a nursing infant. Breast-feeding is not recommended while using this drug and for 1 week after stopping treatment

Talk to your doctor before using Cytoxan if you:

  • Are taking any of the medications that could interact with Cytoxan
  • Have had or are due to have any kind of immunization or vaccination

Cytoxan generic

Cytoxan is the trademark brand name for cyclophosphamide manufactured by Amneal Pharmaceuticals, Inc. A generic version of cyclophosphamide is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Cytoxan savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.