medicationsDepo Medrol

Depo-Medrol Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Depo-Medrol cost savings if eligible

The Depo-Medrol patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Depo-Medrol, regardless of the retail price.

Am I eligible for the Depo-Medrol patient assistance program?

To find out if you are eligible for Depo-Medrol assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Depo-Medrol patient assistance program?

Our application process aims to make it as easy as possible to apply for the Depo-Medrol patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Depo-Medrol.

NiceRx will review your application and determine whether you may be eligible for Depo-Medrol assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Depo-Medrol patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Depo-Medrol.

Is NiceRx a Depo-Medrol coupon provider?

NiceRx is a service provider that helps eligible individuals access the Depo-Medrol patient assistance program. We do not offer trial offers or free Depo-Medrol samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Depo-Medrol coupons, discount cards, or Depo-Medrol copay cards.

Can NiceRx help me get Depo-Medrol cheaper if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Depo-Medrol medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Depo-Medrol cost without insurance?

Depo-Medrol prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Depo-Medrol injectable suspension (40 mg/mL) typically costs $20 for 1 milliliter.

How much does Depo-Medrol cost with insurance?

The copay for Depo-Medrol will vary by the terms of your healthcare plan. To find out what you might need to pay for Depo-Medrol with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Depo-Medrol?

Depo-Medrol is an FDA (U.S. Food and Drug Administration) approved medication distributed by Pharmacia & Upjohn Co Division of Pfizer Inc. Depo-Medrol (methylprednisolone acetate) is an anti-inflammatory glucocorticoid used to treat rheumatoid arthritis, osteoarthritis, bursitis, lupus, psoriasis, ulcerative colitis, allergic conditions, endocrine disorders, and conditions affecting the nervous system, eyes, lungs, and skin.

Depo-Medrol can also be used as an epidural. Discuss the risks and benefits of methylprednisolone with your doctor before use.

What doses of Depo-Medrol are available?

Depo-Medrol is available in injection form, in the following doses: 20 mg in 1 mL single-dose vials.

Depo-Medrol is given as an intramuscular injection into a muscle, into soft tissue, a skin lesion, into the space around a joint as an intra-articular injection. or as an infusion into a vein. Steroid treatments can weaken your immune system, making it easier for you to get an infection. Call your doctor if you have any signs of infection.

Always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Depo-Medrol active ingredients

Depo-Medrol contains methylprednisolone acetate as the active ingredient. It is a 6- methyl derivative of prednisolone. It is classed as a synthetic steroid (cortisone) that prevents inflammation.

Depo-Medrol side effects

The most common side effects of Depo-Medrol in clinical trials include:

  • Injection site reactions
  • Weight gain
  • Slow wound healing
  • Muscle pain or weakness
  • Thinning skin
  • Stomach upset, bloating
  • Headache
  • Changes in your menstruation

In rare instances, Depo-Medrol can cause more serious side effects. These can include:

  • Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing’s syndrome, and hyperglycemia
  • Acute myopathy with high doses of corticosteroids
  • Problems with vision, eye pain, or seeing halos around lights
  • Severe depression, unusual thoughts or behavior
  • Pain in your upper stomach spreading to your back, nausea, and vomiting
  • Bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds
  • Seizures
  • Low potassium – leg cramps, constipation, irregular heartbeats, increased thirst or urination, numbness or tingling, muscle weakness

Your doctor will assess the benefits of using Depo-Medrol against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Depo-Medrol to the FDA. Visit, or call 1-800-FDA-1088.

Depo-Medrol drug interactions

Depo-Medrol can interact with other medications. These include:

  • Live vaccines such as measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, chickenpox, zoster, and influenza
  • Increased risk of gastrointestinal bleeding and ulceration when given with NSAIDs
  • Development of hypokalemia when given with potassium-depleting agents such as amphotericin B or diuretics
  • Azole antifungals such as ketoconazole
  • Cyclosporine
  • Estrogens
  • HIV protease inhibitors
  • Rifamycins such as rifampin
  • St. John’s wort
  • Drugs used to treat seizures such as phenytoin, phenobarbital

This list is not exhaustive and other prescription drugs may interact with Depo-Medrol. Tell your healthcare provider about all the medicines you take, including over-the-counter (non-prescription), and herbal medications you are taking. Also, tell them about any supplements you take.

Depo-Medrol contraindications

You should not use Depo-Medrol if you:

  • Are allergic to the active ingredient methylprednisolone acetate
  • Have had an allergic reaction to any of the other ingredients in Depo-Medrol
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Depo-Medrol if you:

  • Are taking any of the medications that could interact with Depo-Medrol
  • Have a fungal infection
  • Have heart disease, or hypertension (high blood pressure)
  • Have any heart problems such as congestive heart failure
  • Have a thyroid disorder
  • Are diabetic
  • Have fluid retention
  • Have glaucoma or cataracts
  • Have kidney disease
  • Have any liver problems
  • Suffer from seizures, epilepsy, or have recently had a head injury
  • Have herpes simplex infection of the eyes
  • Have stomach ulcers, ulcerative colitis, diverticulitis, or recent intestinal surgery
  • Have osteoporosis or low bone mineral density
  • Have myasthenia gravis
  • Have low potassium blood levels
  • Have systemic sclerosis because an increased incidence of scleroderma renal crisis has been observed with corticosteroid
  • Have any stomach or intestinal problems such as diverticulitis, ulcer, or ulcerative colitis
  • Are pregnant or are planning to become pregnant – It is not known whether Depo-Medrol will harm an unborn baby

Depo-Medrol generic

Depo-Medrol is the trademark brand name for methylprednisolone acetate distributed by Pharmacia & Upjohn Co Division of Pfizer Inc. A generic version of methylprednisolone acetate is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Depo-Medrol savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.