Elaprase Coupon & Prices

Is your Elaprase medication too expensive?

Get notified when Elaprase medication becomes available.

Get Started Now
Medically reviewed by  Jamie Winn, PharmD

Is NiceRx an Elaprase coupon provider?

NiceRx is a service provider that helps eligible individuals access patient assistance programs. We do not offer trial offers or free Elaprase samples. This will likely save you more money than if you were to use Elaprase coupons, discount cards, or Elaprase copay cards.

Elaprase patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

How much does Elaprase cost without insurance?

Elaprase prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Elaprase intravenous solution (2 mg/mL) typically costs $3,300 for 3 milliliters.

How much does Elaprase cost with insurance?

The copay for Elaprase will vary by the terms of your healthcare plan. To find out what you might need to pay for Elaprase with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Elaprase?

Elaprase is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Shire Human Genetics Therapies, Inc. It is a hydrolytic lysosomal glycosaminoglycan (GAG)-specific enzyme indicated for the treatment of Hunter syndrome (Mucopolysaccharidosis II, MPS II).

Hunter syndrome is a genetic condition where the body does not produce enough of the enzyme iduronate-2-sulfatase. This causes the buildup of substances called glycosaminoglycans (GAG) in cells and tissues.

Elaprase has been shown to improve walking capacity in patients 5 years of age and older. In patients 16 months to 5 years of age, no data are available to demonstrate improvement in disease-related symptoms or long-term clinical outcomes. Treatment however has reduced spleen volume similar to that of adults and children 5 years of age and older.

Life-threatening anaphylactic reactions, presenting as respiratory distress, hypoxia, hypotension, urticaria, and/or angioedema of the throat or tongue have occurred in some patients during and up to 24 hours after Elaprase infusions. Patients with reduced respiratory function or acute respiratory disease may be at risk of serious acute exacerbation of their respiratory symptoms due to hypersensitivity reactions and will require additional monitoring.

What doses of Elaprase are available?

Elaprase is available in injection form, in the following doses: 6 mg/3 mL (2 mg/mL) in single-use vials.

Administer 0.5 mg per kg of body weight once every week as an intravenous infusion.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Elaprase active ingredients

Elaprase contains idursulfase as the active ingredient. It belongs to the class of medications called enzyme replacement therapies.

Elaprase side effects

The most common side effects of Elaprase in clinical trials compared to placebo include:

  • Headache
  • Pyrexia
  • Pruritus
  • Flushing
  • Musculoskeletal pain
  • Urticaria
  • Diarrhea
  • Cough
  • Rash
  • Vomiting

In rare instances, Elaprase can cause more serious side effects. These can include:

  • Hypersensitivity reactions including anaphylaxis – the risk of hypersensitivity, serious adverse reactions, and antibody development in Hunter Syndrome Patients with severe genetic mutations, Hunter syndrome patients aged 7 years and younger with complete gene deletion, large gene rearrangement, nonsense, frameshift or splice-site mutations have a higher incidence of hypersensitivity reactions, serious adverse reactions, and anti-idursulfase antibody development
  • Risk of acute respiratory complications – patients with compromised respiratory function or acute febrile or respiratory illness may be at higher risk of life-threatening complications from hypersensitivity reactions

Your doctor will assess the benefits of using Elaprase against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Elaprase to the FDA. Visit, or call 1-800-FDA-1088.

Elaprase drug interactions

Other drugs may interact with Elaprase, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medicines including any supplements you are taking.

Elaprase contraindications

You should not use Elaprase if you:

  • Are allergic to the active ingredient idursulfase
  • Have had an allergic reaction to any of the other ingredients in Elaprase
  • Are less than 16 months of age

Talk to your doctor before using Elaprase if you:

  • Are taking any of the medications that could interact with Elaprase
  • Have asthma or any other lung problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – It is not known whether idursulfase passes into breast milk

Elaprase generic

Elaprase is the trademark brand name for idursulfase manufactured by Shire Human Genetics Therapies, Inc. A generic version of idursulfase is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Elaprase savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.