Empaveli Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Empaveli cost savings if eligible

With our assistance, you could access the Empaveli patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Empaveli patient assistance?

We review each Empaveli enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Empaveli patient assistance program?

Our process makes it as easy as possible to apply for the Empaveli patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Empaveli, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx an Empaveli coupon provider?

NiceRx is not an Empaveli coupon, Empaveli discount card, or Empaveli copay card provider. We do not offer Empaveli manufacturer coupons, Empaveli discounts, rebates, Empaveli savings cards, trial offers, or free Empaveli samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me get Empaveli cheaper if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Empaveli
  • Your insurance company will not pay for your Empaveli prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Empaveli cost without insurance?

Without insurance, Empaveli costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Empaveli subcutaneous solution (1080 mg/20 mL) will cost around $37,000 for 160 milliliters.

How much does Empaveli cost with insurance?

The copay for Empaveli will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Empaveli?

Empaveli is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Apellis Pharmaceuticals, Inc. It is a complement inhibitor indicated for the treatment of adult patients with paroxysmal nocturnal hemoglobinuria (PNH) who are:

  • Treatment naïve
  • Switching from C5 inhibitor Soliris (eculizumab)
  • Switching from C5 inhibitor Ultomiris (ravulizumab)

PNH is a rare, chronic blood disorder characterized by the breakdown of healthy, red blood cells (anemia) by an uncontrolled immune system, blood clots, and defective bone marrow not making enough blood components.

What doses of Empaveli are available?

Empaveli is available in injection form, in the following doses: 1,080 mg/20 mL in a single-dose vial.

The recommended dosage is 1,080 mg by subcutaneous infusion twice weekly.

Empaveli may predispose patient to serious infections, especially those caused by encapsulated bacteria, such as Streptococcus pneumoniae, Neisseria meningitidis types A, C, W, Y, and B, and Haemophilus influenzae type B. Patients should be vaccinated against encapsulated bacteria at least 2 weeks before the first dose of Empaveli unless the risks of delaying treatment outweigh the risks of developing a serious infection.

Empaveli is available only through the Empaveli REMS restricted program under a Risk Evaluation and Mitigation Strategy (REMS).

Please see the full prescribing information for the complete boxed warning. Also, read the medication guide for additional information and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Empaveli active ingredients

The active ingredient of Empaveli is pegcetacoplan.

Empaveli side effects

The most common side effects of Empaveli in clinical trials include:

  • Injection-site reactions
  • Diarrhea, abdominal pain
  • Respiratory tract infection, viral infection
  • Tiredness

In rare instances, Empaveli can cause more serious side effects. These can include:

  • Meningococcal infections that may be life-threatening or fatal
  • Infusion-related Reactions
  • Interference with laboratory tests
  • Allergic reactions – chest pain, difficulty breathing or shortness of breath, swelling of your face, tongue, or throat, feeling light-headed

Your doctor will assess the benefits of using Empaveli against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Empaveli to the FDA. Visit, or call 1-800-FDA-1088.

Empaveli drug interactions

Other drugs may interact with Empaveli, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medication including any supplements you are taking.

Empaveli contraindications

You should not use Empaveli if you:

  • Have hypersensitivity to the active ingredient pegcetacoplan
  • Have had an allergic reaction to any of the other ingredients in Empaveli
  • Are not currently vaccinated against certain encapsulated bacteria unless the risks of delaying treatment outweigh the risks of developing serious bacterial infection with an encapsulated organism
  • Are pregnant or are planning to become pregnant – use effective contraception during treatment and for 40 days after the last dose

Talk to your doctor before using Empaveli if you:

  • Are taking any of the medications that could interact with Empaveli
  • Are breastfeeding or are planning to breastfeed

Empaveli generic

Empaveli is the trademark brand name for pegcetacoplan manufactured by Apellis Pharmaceuticals, Inc. A generic version of pegcetacoplan is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Empaveli savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.