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Endari Patient assistance program

Is your Endari medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Endari medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: Your medication is delivered straight to your door
  • NiceRx Benefit
    Ongoing refills: Your medication is refilled automatically
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

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  • An introduction to NiceRx
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  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Endari cost savings if eligible

If you are eligible to receive your Endari prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Endari patient assistance?

To be eligible for the Endari patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Endari enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Endari patient assistance program?

Applying for the Endari patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Endari, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Endari assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Endari patient assistance program, we will also request your Endari medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx an Endari coupons provider?

NiceRx does not provide Endari coupons, discount cards or copay cards. We do not offer printable Endari manufacturer coupons, Endari discounts, rebates, Endari savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Endari medication with NiceRx.

Can NiceRx help me get Endari if I have insurance?

NiceRx may be able to help you access Endari patient assistance if:

  • You have a high copay or coinsurance responsibility for Endari
  • Your insurance company will not pay for your Endari prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Endari cost without insurance?

Endari prices without insurance will vary by retailer. As a guide, Endari oral powder for reconstitution will typically cost around $1,270 for 60 powders for reconstitution.

How much does Endari cost with insurance?

Your individual healthcare plan will determine the copay of Endari with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Endari?

Endari is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Emmaus Medical Inc. It is an oral L-glutamine treatment for sickle cell anemia and sickle beta-thalassemia, two types of sickle cell disease (SCD). The disease occurs most often in African-Americans, Latinos, and other minority groups. Sickle cell disease is an inherited blood disorder in which red blood cells are abnormally shaped (in a crescent, or “sickle,” shape). This restricts the flow of blood in blood vessels and limits oxygen being delivered to the body’s tissues, leading to severe pain and oxidation damage.

The efficacy of Endari was demonstrated by a reduction in the number of sickle cell crises. A sickle cell crisis is defined as a visit to an emergency facility for sickle cell disease-related painful crises which were treated with a parenterally administered narcotic or parenterally administered ketorolac. Sickle-cell crisis leads to organ damage, anemia, stroke, pulmonary complications, and acute chest syndrome. ENDARI is an amino acid indicated to reduce the acute complications of sickle cell disease (SCD) in adult and pediatric patients 5 years of age and older.

What doses of Endari are available?

Endari is available in oral powder form, in the following doses: 5 grams of L-glutamine oral powder per paper-foil-plastic laminate packet.

Endari oral powder is mixed with a liquid, such as water, milk, apple juice or mixed with soft food such as applesauce or yogurt. 5 grams to 15 grams is taken orally, twice daily based on body weight.

Please read the prescribing information and always speak with a healthcare professional for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Endari active ingredients

Endari contains L-glutamine as the active ingredient.

Endari side effects

The most common side effects of Endari in clinical trials compared to placebo (incidence > 10%) include:

  • Constipation
  • Nausea, headache
  • Abdominal pain
  • Cough
  • Pain in extremity, back pain, and chest pain

Your doctor will assess the benefits of using Endari against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Endari to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Endari drug interactions

There is currently no data for Endari drug interactions. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Endari contraindications

You should not use Endari if you:

  • Are allergic to the active ingredient L-glutamine
  • Are allergic to any of the other ingredients in Endari

Talk to your doctor about your medical condition before using Endari if you:

  • Are taking any of the medications that could interact with Endari
  • Have Crohn’s disease
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Endari generic

Endari is the trademark brand name for L-glutamine manufactured by Emmaus Medical Inc. A generic version of L-glutamine is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Endari savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.