medicationsEpiduo Gel

Epiduo Gel Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

If you need help paying for Epiduo topical gel medication, try NiceRx. We may be able to assist you to get your Epiduo for only $49 per month.*

We work directly with your healthcare provider to help you enroll in the Epiduo gel patient assistance program. NiceRx will handle the full application process for you, supporting you in getting access to affordable Epiduo gel without the hassle and stress.

Your monthly Epiduo gel cost savings if eligible

You can receive your Epiduo gel prescription for a flat fee of just $49 per month, every month. This fee covers the full cost of your Epiduo, regardless of the retail price. You could save:

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
Epiduo Gel 0.1%/2.5% 45gm tube$357.46$49.00$308.46

Am I eligible for the Epiduo gel patient assistance program?

If you meet the patient assistance program eligibility criteria, you could receive your Epiduo without paying the full retail price. We review each Epiduo patient assistance program application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Epiduo gel patient assistance program? 

NiceRx takes the stress out of applying for the Epiduo patient assistance program. Just fill in our enrollment application to get started. Tell us about any medications you’re taking, including Epiduo topical gel. We’ll also ask for details about your healthcare provider, your insurance, and your household income, as this information is required by the pharmaceutical manufacturers who ship your medication.

If we determine you’re eligible, we’ll handle the application process for you and help to enroll you in the Epiduo topical gel patient assistance program. Once you’re accepted and enrolled in the program, we’ll also request your Epiduo topical gel medication refills on your behalf for up to 1 year.

Is NiceRx an Epiduo gel coupon provider?

NiceRx is not an Epiduo gel coupon, an Epiduo gel discount card, or an Epiduo gel copay card. We don’t offer printable Epiduo gel manufacturer coupons, Epiduo gel discounts, rebates, Epiduo gel savings cards, trial offers, or free Epiduo gel samples.

NiceRx is a service provider that helps eligible individuals access the Epiduo gel patient assistance program. If you’re looking for coupons for Epiduo gel or cheap Epiduo gel, keep in mind you can likely save more with NiceRx. When obtaining your Epiduo gel medication through NiceRx, your total cost for the medication will always be $49 per month.

Can NiceRx help me get Epiduo gel if I have insurance?

If your insurance company won’t pay for your Epiduo topical gel medication, or you have a high copay or coinsurance responsibility, NiceRx may be able to help. We may be able to help even if you don’t have insurance.

How much is Epiduo gel with insurance?

The cost of Epiduo gel will vary by the healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Remember, if you’re approved for assistance, you’ll likely save more if you get your Epiduo topical gel medication through NiceRx.

How much is Epiduo gel without insurance?

Epiduo gel prices without insurance will vary depending on where you buy it. Epiduo topical gel (0.1%-2.5%) usually costs around $440 for a 45mg bottle. With NiceRx you’ll always pay a flat monthly fee of $49.

What is Epiduo gel?

Epiduo gel is a prescription medication that is used to treat acne (acne vulgaris). It’s a topical treatment, which means that it’s applied directly to the affected skin. Epiduo topical gel helps fight acne by clearing dead skin cells and spots, killing bacteria, and reducing inflammation. Regular use of Epiduo topical gel can reduce the severity and duration of acne breakouts, limiting the number of spots and clearing them up faster.

Acne is a skin condition that can persist for months to years. It’s caused by hair follicles (the small holes in your skin from which hairs grow) getting blocked and forming spots. Follicles are usually blocked by dead skin cells and the oil your skin produces, called sebum. The blocked follicles form spots, usually blackheads and whiteheads at first. If the follicles become infected with bacteria however, the spots can become more severe, forming pustules and cysts. The infection can cause swelling within the skin too. Severe acne with inflammation can result in scarring.

Epiduo gel active ingredients

Epiduo topical gel contains two active ingredients, benzoyl peroxide, and adapalene. Benzoyl peroxide is an antibiotic which kills the bacterial infections that can accompany acne. It can also remove dead skin cells which can block your pores and cause acne. Adapalene is a retinoid, which is a type of molecule similar to vitamin A. When applied to the skin, it can cause dead skin cells to be shed faster and new skin cells to replace them. This can help clear the skin of spots and even reduce the appearance of acne scars. Adapalene can also reduce inflammation in the skin caused by acne. 

Research has repeatedly shown that these two active ingredients when used together are more effective than either used alone.

Epiduo topical gel side effects & Epiduo topical gel drug interactions

Like all medicines, Epiduo topical gel can cause side effects, although not everybody gets them, or will experience the same ones. Epiduo side effects tend to be mild to moderate. They mostly occur on the skin where the gel is used, and they often reduce in severity as your skin gets used to the medication. Common Epiduo side effects include skin dryness, irritation, redness, rashes, scaling, and a burning sensation. More serious, but rarer side effects can include swelling, skin discoloration, and more severe irritation and burning.

Epiduo can interact with other acne products that contain retinoids or benzoyl peroxide and shouldn’t be used alongside them. It also shouldn’t be used at the same time as any face products that dry, exfoliate, or otherwise irritate your skin.

Epiduo gel warnings & precautions

Don’t use Epiduo topical gel if you:

  • Are allergic to the active ingredients benzoyl peroxide or adapalene
  • Are allergic to any of the other ingredients of Epiduo topical gel (listed in the leaflet which comes with your medication)
  • Are pregnant
  • Are under 9 years of age

You may be able to use Epiduo gel when breastfeeding. Talk to your physician about doing so. 

Wash your hands after using Epiduo and make sure you don’t get it on other parts of your body. Don’t put Epiduo topical gel on skin that has cuts, scrapes, sunburn, or eczema. Make sure it doesn’t get into your eyes, nostrils, mouth, or on your hair. 

Avoid exposure to strong sunlight and excessive use of UV lamps when using Epiduo gel, as it can make your skin more sensitive to sun damage. 

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.