Erwinaze Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Erwinaze cost savings if eligible

If you are eligible to receive your Erwinaze prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Erwinaze patient assistance?

To be eligible for the Erwinaze patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Erwinaze enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Erwinaze patient assistance program?

Applying for the Erwinaze patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Erwinaze, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Erwinaze assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Erwinaze patient assistance program, we will also request your Erwinaze medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx an Erwinaze coupon provider?

NiceRx does not provide Erwinaze coupons, discount cards or copay cards. We do not offer printable Erwinaze manufacturer coupons, Erwinaze discounts, rebates, Erwinaze savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Erwinaze medication with NiceRx.

Can NiceRx help me get Erwinaze cheaper if I have insurance?

NiceRx may be able to help you access Erwinaze patient assistance if:

  • You have a high copay or coinsurance responsibility for Erwinaze
  • Your insurance company will not pay for your Erwinaze prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Erwinaze cost without insurance?

Erwinaze prices without insurance will vary by retailer. As a guide, Erwinaze injectable powder for injection 10000 intl units will typically cost around $21,000 for 5 powders for injection.

How much does Erwinaze cost with insurance?

Your individual healthcare plan will determine the copay of Erwinaze with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Erwinaze?

Erwinaze (asparaginase Erwinia chrysanthemi/Erwinia asparaginase) is an FDA (U.S. Food and Drug Administration) approved medication manufactured by EUSA Pharma (USA), Inc.

It is an asparagine-specific enzyme indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of patients with acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma for persons who are hypersensitive to Oncaspar (pegaspargase), or as induction therapy for patients aged 65 years and older.

What doses of Erwinaze are available?

Erwinaze is available in lyophilized powder form, in the following doses: 10,000 International Units per vial.

The recommended dose for each planned dose of pegaspargase is 25,000 International Units/m2, administered intramuscularly or intravenously 3 times a week (Monday/Wednesday/Friday) for 6 doses. To substitute for a dose of native E. coli asparaginase, the recommended dose is 25,000 International Units/m2 administered intramuscularly or intravenously for each scheduled dose of native E. coli asparaginase.

Limit the volume of reconstitution at a single injection site to 2 mL. If the reconstituted dose to be administered is greater than 2 mL, use multiple injection sites.

Outside of the U.S., Erwinaze is sold under the name Erwinase. Please consult local labeling and prescribing information for product information specific to your country. Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Erwinaze active ingredients

Asparaginase Erwinia chrysanthemi catalyzes the breakdown of asparagine to aspartic acid and ammonia, reducing circulating levels of asparagine. The mechanism of action of Erwinaze is thought to be based on the inability of leukemic cells to synthesize asparagine due to a lack of asparagine synthetase activity, resulting in cytotoxicity specific for leukemic cells that depend on an external; source of amino acid asparagine for their protein metabolism and survival.

Erwinaze side effects

The most common side effects of Erwinaze in clinical trials include:

  • Fever
  • Local reactions
  • Vomiting, nausea
  • Abdominal pain and diarrhea

In rare instances, Erwinaze can cause more serious adverse effects. These can include:

  • Serious hypersensitivity reactions, including anaphylaxis
  • Severe or hemorrhagic pancreatitis
  • Glucose intolerance – hyperglycemia
  • Thrombosis, hemorrhage – serious thrombotic events
  • Pancreatitis
  • Transaminases abnormal
  • Hyperbilirubinemia

Your doctor will assess the benefits of using Erwinaze against your risk of side effects. Patients are encouraged to report negative side effects or adverse events of Erwinaze to the FDA. Visit, or call 1-800-FDA-1088.

Erwinaze drug interactions

Other drugs may interact with Erwinaze, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medicines including any supplements you are taking.

Erwinaze contraindications

You should not use Erwinaze if you:

  • Have a history of serious hypersensitivity reactions to the active ingredient asparaginase Erwinia chrysanthemi
  • Have had an allergic reaction to any of the other ingredients in Erwinaze
  • Have a history of serious pancreatitis with prior L-asparaginase therapy
  • Have a history of serious thrombosis with prior L-asparaginase therapy
  • Have a history of serious hemorrhagic events with prior L-asparaginase therapy
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Erwinaze if you:

  • Are taking any of the medications that could interact with Erwinaze
  • Have problems with your liver or pancreas
  • Have bleeding problems
  • Have a blood clot
  • Have diabetes
  • Are breastfeeding or are planning to breastfeed

Erwinaze generic

Erwinaze is the trademark brand name for asparaginase Erwinia chrysanthemi manufactured by EUSA Pharma (USA), Inc. A generic version of asparaginase Erwinia chrysanthemi is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Erwinaze savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.