medicationsHerceptin Hylecta

Herceptin Hylecta Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Herceptin Hylecta cost savings if eligible

If you are eligible for the Herceptin Hylecta patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Herceptin Hylecta prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Herceptin Hylecta patient assistance program?

We will review your application to determine whether you are eligible for the Herceptin Hylecta patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Herceptin Hylecta patient assistance program?

We make it as easy as possible to apply for the Herceptin Hylecta patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Herceptin Hylecta. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Herceptin Hylecta assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Herceptin Hylecta patient assistance program, and we will automatically request your Herceptin Hylecta medication refills for up to 1 year.

Is NiceRx a Herceptin Hylecta coupon provider?

We are a service provider that helps eligible individuals access the Herceptin Hylecta patient assistance program. That means that we do not offer printable Herceptin Hylecta manufacturer coupons, Herceptin Hylecta discounts, or free Herceptin Hylecta samples. We are not a Herceptin Hylecta coupon provider or Herceptin Hylecta discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Herceptin Hylecta cheaper if I have insurance?

We may be able to help you to access Herceptin Hylecta patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Herceptin Hylecta medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Herceptin Hylecta cost without insurance?

Herceptin Hylecta cost without insurance will vary depending on where you buy it. As a guide, Herceptin Hylecta subcutaneous solution (10,000 units-600 mg/5 mL) usually costs $4,900 for 5 milliliters. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Herceptin Hylecta cost with insurance?

The copay for Herceptin Hylecta with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Herceptin Hylecta?

Herceptin Hylecta is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Genentech, Inc. Approval was based on two randomized trials, HannaH and SafeHER. Herceptin Hylecta is a combination of trastuzumab, a humanized IgG1 kappa monoclonal antibody, and hyaluronidase, an endoglycosidase. It is indicated in adults for the treatment of HER2-overexpressing breast cancer.

Herceptin Hylecta can be used:

  • As part of an adjuvant treatment course, including the chemotherapy regimen drugs doxorubicin, cyclophosphamide, and either paclitaxel or docetaxel
  • With the chemotherapy drugs docetaxel and carboplatin
  • As a single agent after treatment with multiple other therapies, including an anthracycline (doxorubicin) based therapy

Herceptin Hylecta can result in

  • Subclinical and clinical cardiac failure manifesting as CHF, and decreased LVEF, with the greatest risk when administered concurrently with anthracyclines. Discontinue Herceptin Hylecta for cardiomyopathy
  • Pulmonary toxicity – discontinue Herceptin Hylecta for anaphylaxis, angioedema, interstitial pneumonitis, or acute respiratory distress syndrome
  • Embryo-fetal toxicity – exposure during pregnancy can result in oligohydramnios, in some cases complicated by pulmonary hypoplasia and neonatal death. Patients are advised to use effective contraception

What doses of Herceptin Hylecta are available?

Herceptin Hylecta is available as an injection formulation, in the following doses: 600 mg trastuzumab and 10,000 units of hyaluronidase per 5 mL (120 mg/2,000 units per mL) solution in a single-dose vial.

Herceptin Hylecta is for subcutaneous use only and has different dosage and administration instructions than intravenous trastuzumab products. Do not substitute Herceptin Hylecta for or with ado-trastuzumab emtansine. The recommended dose of Herceptin Hylecta is 600 mg/10,000 units (600 mg trastuzumab and 10,000 units hyaluronidase) administered subcutaneously over approximately 2-5 minutes once every three weeks.

Please see the full prescribing information for the complete boxed warning and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Herceptin Hylecta active ingredients

Herceptin Hylecta contains trastuzumab and hyaluronidase-oysk as the active ingredients.

Herceptin Hylecta side effects

The most common side effects of Herceptin Hylecta in clinical trials for:

  • Adjuvant breast cancer are fatigue, arthralgia, myalgia, diarrhea, injection site reaction, upper respiratory tract infection, rash, nausea, headache, edema, flushing, pyrexia, cough, shortness of breath, and chest pain
  • Metastatic breast cancer are fever, chills, headache, infection, congestive heart failure, insomnia, cough, and rash

In rare instances, Herceptin Hylecta can cause more serious side effects. These can include:

  • Exacerbation of chemotherapy-induced neutropenia
  • Hypersensitivity and administration-related reactions including anaphylaxis

Your doctor will assess the benefits of using Herceptin Hylecta against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Herceptin Hylecta to the FDA. Visit, or call 1-800-FDA-1088.

Herceptin Hylecta drug interactions

Herceptin Hylecta can interact with other medications. These include:

  • Anthracycline-based therapy – avoid anthracycline for up to 7 months after stopping treatment. If anthracyclines are used, carefully monitor cardiac function

This list is not exhaustive and other prescription drugs may interact with Herceptin Hylecta.

Herceptin Hylecta contraindications

You should not use Herceptin Hylecta if you:

  • Are allergic to the active ingredient trastuzumab and hyaluronidase-oysk
  • Are allergic to any of the other ingredients in Herceptin Hylecta
  • Are pregnant or are planning to become pregnant – contraception should be used while receiving treatment and for 7 months after your last dose
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Herceptin Hylecta if you:

  • Are taking any of the medications that could interact with Herceptin Hylecta
  • Have heart problems
  • Have high blood pressure
  • Have recently had an infection

Herceptin Hylecta generic

Herceptin Hylecta is the trademark brand name for trastuzumab and hyaluronidase-oysk manufactured by Genentech, Inc. A generic version of trastuzumab and hyaluronidase-oysk is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Herceptin Hylecta savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.