Hycamtin Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Hycamtin cost savings if eligible

If you are eligible for the Hycamtin patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Hycamtin prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Hycamtin patient assistance program?

We will review your application to determine whether you are eligible for the Hycamtin patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Hycamtin patient assistance program?

We make it as easy as possible to apply for the Hycamtin patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Hycamtin. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Hycamtin assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Hycamtin patient assistance program, and we will automatically request your Hycamtin medication refills for up to 1 year.

Is NiceRx a Hycamtin coupon provider?

We are a service provider that helps eligible individuals access the Hycamtin patient assistance program. That means that we do not offer printable Hycamtin manufacturer coupons, Hycamtin discounts, or free Hycamtin samples. We are not a Hycamtin coupon provider or Hycamtin discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Hycamtin cheaper if I have insurance?

We may be able to help you to access Hycamtin patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Hycamtin medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Hycamtin cost without insurance?

Hycamtin cost without insurance will vary depending on where you buy it. As a guide, Hycamtin intravenous powder for injection 4 mg usually costs $1,200 for 1 powder for injection. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Hycamtin cost with insurance?

The copay for Hycamtin with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Hycamtin?

Hycamtin is an FDA (U.S. Food and Drug Administration) approved medication manufactured by GlaxoSmithKline. It is classed as an anticancer antineoplastics topoisomerase i inhibitor. Camptothecan analogs are derived from the Asian “Happy Tree” (Camptotheca acuminata).

Topoisomerase inhibitors are drugs that interfere with the action of topoisomerase enzymes (topoisomerase I and II). Topoisomerase enzymes control the manipulation of the structure of DNA necessary for cell division and replication.

Hycamtin is indicated for the treatment of:

  • Patients with metastatic ovarian cancer (carcinoma) after disease progression on or after initial or subsequent chemotherapy, as a single agent
  • Patients with small-cell lung cancer (SCLC) platinum-sensitive disease who progressed at least 60 days after initiation of first-line chemotherapy, as a single agent. (Topotecan is often given in combination with paclitaxel as a first-line treatment for extensive-stage small-cell lung cancer)
  • Patients with Stage IV-B, recurrent, or persistent cervical cancer which is not amenable to curative treatment, in combination with cisplatin

What doses of Hycamtin are available?

Hycamtin is available in injection form, in the following doses: 4 mg (free base) lyophilized powder in a single-dose vial.

Ovarian cancer and Small cell lung cancer – 1.5 mg/m2 by intravenous infusion over 30 minutes daily for 5 consecutive days, starting on Day 1 of a 21-day cycle.

Cervical cancer – 0.75 mg/m2 by intravenous infusion over 30 minutes on Days 1, 2, and 3, with cisplatin 50 mg/m2 on Day 1, of a 21-day cycle.

Reduce the dose if creatinine clearance (CLcr) is 20 to 39 mL/min due to renal impairment

Always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Hycamtin active ingredients

Hycamtin contains topotecan hydrochloride as the active ingredient. Topoisomerase I induces reversible single-strand breaks in DNA. Topotecan’s mechanism of action is to bind to the topoisomerase I-DNA complex and prevents re-ligation of these single-strand breaks. The cytotoxicity of topotecan is thought to be due to double-strand DNA damage produced during DNA synthesis when replication enzymes interact with the complex formed by topotecan, topoisomerase I, and DNA.

Hycamtin side effects

The most common side effects of Hycamtin in clinical trials include:

  • Administration site conditions
  • Decreased bone marrow function. This effect may lead to a low number of blood cells such as red cells, white cells, and platelets
  • Neutropenia
  • Anemia (reduced red blood cell count)
  • Thrombocytopenia (reduced platelet count)
  • Febrile neutropenia (reduced white blood cells)
  • Nausea, vomiting, tiredness, diarrhea
  • Asthenia, dyspnea, pneumonia, abdominal pain
  • Pain, vomiting, and infection
  • Feeling generally weak and tired
  • Weight loss and loss of appetite (anorexia)
  • Constipation
  • Burning sensation when urinating, which may be caused by a urinary infection
  • Fever
  • Alopecia (hair loss)
  • Bone pain
  • Mouth sores
  • Rash
  • Shortness of breath
  • Cough
  • Headache

In rare instances, Hycamtin can cause more serious side effects. These can include:

  • Interstitial lung disease (ILD)
  • Extravasation and tissue injury
  • Embryo-fetal toxicity – use effective contraception during treatment

Your doctor will assess the benefits of using Hycamtin against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Hycamtin to the FDA. Visit, or call 1-800-FDA-1088.

Hycamtin drug interactions

Hycamtin can interact with other medications. These include:

  • Filgrastim
  • Pegfilgrastim
  • Sargramostim

This list is not exhaustive and other prescription drugs may interact with Hycamtin.

Hycamtin contraindications

You should not use Hycamtin if you:

  • Are allergic to the active ingredient topotecan hydrochloride
  • Are allergic to any of the other ingredients in Hycamtin
  • Have a history of severe hypersensitivity reactions to topotecan
  • Are breastfeeding or are planning to breastfeed
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Hycamtin if you:

  • Are taking any of the medications that could interact with Hycamtin
  • Have severe diarrhea
  • Have kidney disease
  • Have lung problems
  • Have had a chest X-ray or radiation treatment of your chest area

Hycamtin generic

Hycamtin is the trademark brand name for topotecan hydrochloride manufactured by GlaxoSmithKline. A generic version of topotecan hydrochloride is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Hycamtin savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.