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Increlex Patient assistance program

Is your Increlex medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Increlex medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: Your medication is delivered straight to your door
  • NiceRx Benefit
    Ongoing refills: Your medication is refilled automatically
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Increlex cost savings if eligible

If you are eligible for the Increlex patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Increlex through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Increlex patient assistance program?

You could receive your Increlex without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies who are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Increlex patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Increlex.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Increlex patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Increlex medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx an Increlex coupon provider?

At NiceRx, we help eligible individuals access the Increlex patient assistance program. This means that we are not an Increlex coupon, an Increlex discount card, or an Increlex copay card provider. We do not offer any medication trial offers, or free Increlex samples.

Can NiceRx help me get Increlex cheaper if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Increlex medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Increlex cost without insurance?

Increlex costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Increlex subcutaneous solution (10 mg/mL) will typically cost around $59,300 for 40 milliliters. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Increlex cost with insurance?

The copay of Increlex will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Increlex?

Increlex is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Ipsen Biopharmaceuticals, Inc. Increlex (mecasermin) injection contains human insulin-like growth factor-1 (rhIGF-1) produced by recombinant DNA technology. Increlex is indicated for the treatment of growth failure in children with severe primary IGF-1 deficiency (SPIGFID) or with growth hormone (GH) gene deletion who have developed neutralizing antibodies to GH.

The approval of Increlex was based on results from a clinical study involving 81 treatment-naïve patients with SPIGFD, with a primary efficacy endpoint of height velocity, which was compared with pre-treatment levels. The trial showed that long-term Increlex treatment resulted in a sustained increase in height velocity above pre-treatment levels for up to eight years, with the largest response observed in the first year.

What doses of Increlex are available?

Increlex is available as a sterile solution supplied in a multiple-dose glass vial at a concentration of 10 mg per mL (40 mg per vial).

Increlex is administered as a subcutaneous injection. Injection sites should be rotated to a different site (upper arm, thigh, buttock, or abdomen) with each injection to help prevent lipohypertrophy.

The recommended starting dose is 0.04 to 0.08 mg/kg (40 to 80 micrograms/kg) twice daily. If well-tolerated for at least one week, the dose may be increased by 0.04 mg/kg per dose, to the maximum dose of 0.12 mg/kg given twice daily.

Please read the full prescribing information for the additional information and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Increlex active ingredients

Increlex contains mecasermin as the active ingredient.

Increlex side effects

The most common side effects of Increlex in clinical trials include:

  • Injection site reactions
  • Hypoglycemia (low blood sugar) – Your child should always keep a source of sugar such as orange juice, glucose gel, candy, or milk available in case symptoms of low blood sugar happen
  • Tonsillar hypertrophy (swollen tonsils)

In rare instances, Increlex can cause more serious side effects. These can include:

  • Infections and infestations – otitis media, (especially in the middle ear)
  • Local and systemic hypersensitivity and allergic reactions, including anaphylaxis – A low number of cases requiring hospitalization have been reported
  • Intracranial hypertension
  • Lymphoid tissue hypertrophy (tonsillar/adenoidal hypertrophy)
  • Slipped capital femoral epiphysis (SCFE) – evaluate any child with the onset of a limp or hip/knee pain for possible SCFE
  • Progression of scoliosis – monitor any child with scoliosis for progression of the spine curve
  • Malignant neoplasia has been observed in pediatric patients treated with Increlex
  • Risk of serious adverse reactions in infants due to benzyl alcohol, a preservative in Increlex. Use of Increlex in infants is not recommended

Your doctor will assess the benefits of using Increlex against your risk of adverse events. Patients are encouraged to report negative side effects or adverse reactions of Increlex to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Increlex drug interactions

Other drugs may interact with Increlex, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medicines including any supplements you are taking.

Increlex contraindications

You should not use Increlex if you:

  • Are allergic to the active ingredient mecasermin
  • Are allergic to any of the other ingredients in Increlex
  • Have known hypersensitivity to mecasermin
  • Have closed epiphysis
  • Have malignant neoplasia
  • Are less than 2 years of age

Talk to your doctor before using Increlex if you:

  • Are taking any of the medications that could interact with Increlex
  • Have diabetes
  • Have kidney disease
  • Have liver disease
  • Have a curved spine (scoliosis)
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Increlex generic

Increlex is the trademark brand name for mecasermin manufactured by Ipsen Biopharmaceuticals, Inc. A generic version of mecasermin is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Increlex savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.