Istodax Coupon & Prices

Is your Istodax medication too expensive?

Get notified when Istodax medication becomes available.

Get Started Now
Medically reviewed by  Jamie Winn, PharmD

Your monthly Istodax cost savings if eligible

With our assistance, you could access the Istodax patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Istodax patient assistance?

We review each Istodax enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Istodax patient assistance program?

Our process makes it as easy as possible to apply for the Istodax patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Istodax, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx an Istodax coupon provider?

NiceRx is not an Istodax coupon, Istodax discount card, or Istodax copay card provider. We do not offer Istodax manufacturer coupons, Istodax discounts, rebates, Istodax savings cards, trial offers, or free Istodax samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me get Istodax cheaper if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Istodax
  • Your insurance company will not pay for your Istodax prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Istodax cost without insurance?

Without insurance, Istodax costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Istodax intravenous powder for injection 10 mg will cost around $3,400 for 1 powder for injection.

How much does Istodax cost with insurance?

The copay for Istodax will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Istodax?

Istodax is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Celgene Corporation. It is a histone deacetylase (HDAC) inhibitor indicated for the treatment of cutaneous T-cell lymphoma (CTCL) and peripheral T-cell lymphoma (PTCL) in patients who have received at least one prior systemic therapy.

What doses of Istodax are available?

Istodax is available in injection form, in the following doses: 10 mg, supplied with one diluent vial containing 2 mL of solution.

14 mg/m2 is administered intravenously (IV) over a 4-hour period on days 1, 8, and 15 of a 28-day cycle. Repeat cycles every 28 days. Treatment discontinuation or interruption with or without dose reduction to 10 mg/m2 may be needed to manage adverse drug reactions. Continue treatment until disease progression or intolerable toxicity.

Please read the prescribing information and the FDA-approved patient labeling and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Istodax active ingredients

The active ingredient of Istodax is romidepsin. It belongs to a class of drugs called histone deacetylase inhibitors (HDAC). HDACs are enzymes that control histones, which are important proteins in the formulation of DNA. Istodax blocks HDACs so histones cannot be used properly. This interferes with the genetic makeup of cancer cells, leading to cell death.

Istodax side effects

The most common side effects of Istodax in clinical trials include:

  • Nausea, vomiting
  • Tiredness
  • Infections
  • Anorexia
  • Loss of appetite
  • Changes in sense of taste
  • Constipation
  • Itching
  • Anemia (low red blood cells)
  • Thrombocytopenia
  • Neutropenia (low white blood count)
  • Leukopenia
  • Lymphopenia
  • Electrocardiographic (ECG) T-wave changes

In rare instances, Istodax can cause more serious side effects. These can include:

  • Reactivation of hepatitis B virus infection
  • QT prolongation – ensure that potassium and magnesium are within the normal range before administration of Istodax
  • Serious infections – symptoms include fever, cough, shortness of breath with or without chest pain, burning with urination, flu-like symptoms, muscle aches
  • Tumor Lysis Syndrome (TLS) – rapid breakdown of cancer cells

Your doctor will assess the benefits of using Istodax against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Istodax to the FDA. Visit, or call 1-800-FDA-1088.

Istodax drug interactions

Istodax can interact with other medications. These include:

  • Coumadin derivatives – warfarin
  • Strong CYP3A4 inhibitors
  • Potent CYP3A4 inducers
  • Azole antifungals – itraconazole, and ketoconazole
  • Rifamycins such as rifabutin, rifampin
  • St. John’s wort
  • Drugs used to treat seizures such as carbamazepine
  • Hormonal birth control such as pills, patches, or rings

This list is not exhaustive and other prescription drugs may interact with Istodax.

Istodax contraindications

You should not use Istodax if you:

  • Are allergic to the active ingredient romidepsin
  • Are allergic to any of the other ingredients in Istodax
  • Are pregnant or are planning to become pregnant – Embryo-fetal toxicity may occur and harm your unborn baby. Females of reproductive potential are advised to use effective contraception during treatment and for 1 month after the last dose

Talk to your doctor before using Istodax if you:

  • Are taking any of the medications that could interact with Istodax
  • Have heart problems or a heart rhythm disorder
  • Have long QT syndrome (in you or a family member)
  • Have kidney disease
  • Have hepatic impairment (especially hepatitis B)
  • Have an electrolyte imbalance
  • Are breastfeeding or are planning to breastfeed

Istodax generic

Istodax is the trademark brand name for romidepsin manufactured by Celgene Corporation. A generic version of romidepsin is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Istodax savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.