medicationsJentadueto Xr

Jentadueto XR Coupon & Prices

Is your Jentadueto XR medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Jentadueto XR medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Jentadueto XR cost savings if eligible

If you are eligible for the Jentadueto XR patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Jentadueto XR through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

StrengthAvg. monthly price at
a US pharmacy
NiceRx monthly
Monthly savings
with NiceRx
2.5mg/1000mg - 60 tablets$420.00$49.00$371.00

Am I eligible for the Jentadueto XR patient assistance program?

You could receive your Jentadueto XR without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Jentadueto XR patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Jentadueto XR.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Jentadueto XR patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Jentadueto XR medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Jentadueto XR coupons provider?

At NiceRx, we help eligible individuals access the Jentadueto XR patient assistance program. This means that we are not a Jentadueto XR coupon, a Jentadueto XR discount card, or a Jentadueto XR copay card provider. We do not offer any medication trial offers, or free Jentadueto XR samples.

Can NiceRx help me get Jentadueto XR if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Jentadueto XR medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Jentadueto XR cost without insurance?

Jentadueto XR costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Jentadueto XR oral tablet, extended-release (2.5 mg-1000 mg) will typically cost around $516 for 60 tablets. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Jentadueto XR cost with insurance?

The copay of Jentadueto XR will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Jentadueto XR?

Jentadueto XR is an FDA (U.S. Food and Drug Administration) approved medication distributed by Boehringer Ingelheim Pharmaceuticals, Inc. Jentadueto XR is a dipeptidyl peptidase-4 (DPP-4) inhibitor and biguanide combination product indicated with diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus when treatment with both linagliptin and metformin is appropriate. Jentadueto XR is not for the treatment of type 1 diabetes or diabetic ketoacidosis and has not been studied in patients with a history of pancreatitis.

Risk of lactic acidosis – See full prescribing information for complete boxed warning. Cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias. Laboratory abnormalities included elevated blood lactate levels, anion gap acidosis, increased lactate/pyruvate ratio; and metformin plasma levels generally >5 mcg/mL. Risk factors include renal impairment, concomitant use of certain drugs, age ≥ 65 years old, radiological studies with contrast, surgery and other procedures, hypoxic states, excessive alcohol intake, and hepatic impairment. Steps to reduce the risk of and manage metformin-associated lactic acidosis in these high-risk groups are provided in the full prescribing information. If lactic acidosis is suspected, discontinue treatment and introduce general supportive measures in a hospital setting. Prompt hemodialysis is recommended.

What doses of Jentadueto XR are available?

Jentadueto XR is available in tablet form, in the following doses: 5 mg linagliptin/1000 mg metformin hydrochloride extended-release and 2.5 mg linagliptin/1000 mg metformin hydrochloride extended-release.

Please see the full prescribing information and medication guide for the full drug information and safety information. Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Jentadueto XR active ingredients

Jentaduedo XR contains linagliptin and metformin hydrochloride extended-release as the active ingredients.

Jentadueto XR side effects

The most common adverse reactions of Jentadueto XR in clinical trials include:

  • Nasopharyngitis
  • Diarrhea

In rare instances, Jentadueto XR can cause more serious side effects. These can include:

  • Lactic acidosis – get emergency medical help if you have unusual muscle pain, trouble breathing, irregular heartbeats, dizziness, stomach pain, vomiting, or if you feel cold, tired, or very weak
  • Pancreatitis, including fatal pancreatitis
  • Hypoglycemia (low blood glucose) – low blood sugar levels include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, or tingling hands/feet. Consider lowering the dose of the insulin secretagogue (sulfonylurea) or insulin to reduce the risk of hypoglycemia
  • Hypersensitivity reactions including anaphylaxis, angioedema, and exfoliative skin conditions
  • Vitamin B12 deficiency – monitor hematologic parameters annually
  • Arthralgia – severe and disabling arthralgia has been reported in patients taking DPP-4 inhibitors. Consider as a possible cause for severe joint pain and discontinue
  • Bullous pemphigoid – report the development of blisters or erosions
  • Macrovascular outcomes

Get emergency medical help if you have symptoms of a serious allergic reaction such as hives, problems breathing, swelling in your face or throat, severe skin reaction, fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering, and peeling.

Your doctor will assess the benefits of using Jentadueto XR against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Jentadueto XR to the FDA. Visit, or call 1-800-FDA-1088.

Jentadueto XR drug interactions

Jentadueto XR can interact with other medications. These include:

  • Carbonic anhydrase inhibitors
  • Drugs that are eliminated by renal tubular secretion – cimetidine
  • Alcohol can potentiate the effect of metformin on lactate metabolism
  • Strong P-glycoprotein/CYP3A4 inducer – rifampin)

This list is not exhaustive and other prescription drugs may interact with Jentadueto XR. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Jentadueto XR contraindications

You should not use Jentadueto XR if you:

  • Have a history of hypersensitivity reactions to linagliptin or metformin
  • Are allergic to any of the other ingredients in Jentadueto XR
  • Are pregnant or are planning to become pregnant
  • Have severe renal impairment (eGFR below 30 mL/min/1.73 m2)
  • Have metabolic acidosis, including diabetic ketoacidosis

Talk to your doctor about your medical conditions before using Jentadueto XR if you:

  • Are taking any of the medications that could interact with Jentadueto XR
  • Are pregnant or are planning to become pregnant (premenopausal females have a potential for unintended pregnancy)
  • Are geriatric – assess renal function more frequently
  • Have hepatic impairment
  • Have heart disease – risk of heart failure
  • Have pancreatitis
  • Have gallstones
  • Have alcoholism
  • Have high triglycerides
  • Are breastfeeding or are planning to breastfeed

Jentadueto XR generic

Jentadueto XR is the trademark brand name for linagliptin and metformin hydrochloride extended-release distributed by Boehringer Ingelheim Pharmaceuticals, Inc. A generic version of linagliptin and metformin hydrochloride extended-release is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Jentadueto XR savings through NiceRx.

Related conditions

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.