Krystexxa Coupon & Prices

Is your Krystexxa medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Krystexxa medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Krystexxa cost savings if eligible

The Krystexxa patient assistance program can provide your medication for free. We simply charge $49 a month per medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Krystexxa, regardless of the retail price.

Am I eligible for the Krystexxa patient assistance program?

To find out if you are eligible for Krystexxa assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Krystexxa patient assistance program?

Our application process aims to make it as easy as possible to apply for the Krystexxa patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Krystexxa.

NiceRx will review your application and determine whether you may be eligible for Krystexxa assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Krystexxa patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Krystexxa.

Is NiceRx a Krystexxa coupons provider?

NiceRx is a service provider that helps eligible individuals access the Krystexxa patient assistance program. We do not offer trial offers or free Krystexxa samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Krystexxa coupons, discount cards, or Krystexxa copay cards.

Can NiceRx help me get Krystexxa if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Krystexxa medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much is Krystexxa with insurance?

The cost of Krystexxa will vary by the terms of your healthcare plan. To find out what you might need to pay for Krystexxa with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

How much does Krystexxa cost without insurance?

Krystexxa prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Krystexxa intravenous solution (8 mg/mL) typically costs $26,000 for 1 milliliter.

What is Krystexxa?

Krystexxa contains the prescription medicine pegloticase. Pegloticase breaks down uric acid into a harmless chemical which is then excreted from the body. Krystexxa injections are used in adults for the treatment of the signs and symptoms of chronic gout that has not been treated successfully with other medication at the maximum dose available, or when other medication is not recommended. Krystexxa is normally given after other treatments have been tried.

Krystexxa is not recommended for treatment when there are high levels of uric acid in the body, but there are no signs or symptoms of gout. Krystexxa is normally given once every 2 weeks as an infusion into a vein. The infusion can take at least two hours to complete as it must be given slowly.

You may find that you have an increase in gout flare-ups when you first start taking this medication. Your progress will be monitored regularly. Inform your doctor if you see no improvement in symptoms after 3 months. Your doctor may prescribe other medications for your gout in the first 6 months of treatment with Krystexxa.

Krystexxa active ingredients

Krystexxa contains pegloticase which is an enzyme that specifically acts on uric acid. Pegloticase works by increasing the rate at which uric acid is oxidized in the body to form allantoin, thereby reducing the uric acid concentration. Allantoin is a chemically inactive, water-soluble substance that is easily removed from the body through renal excretion in the urine.

Krystexxa side effects

The most common side effects caused by Krystexxa include:

  • Gout flare ups
  • Allergic reactions
  • Vomiting
  • Constipation
  • Sore throat
  • Bruising

In rare instances, Krystexxa can cause more serious side effects. These can include:

  • Chest pain
  • Flushing

Your doctor will assess the benefits of using Krystexxa against your risk of side effects.

Krystexxa drug interactions

Krystexxa can interact with other medications. These include:

  • Other treatments for gout – allopurinol, probenecid, sulfinpyrazone
  • Treatment for severe combined immune deficiency disease (SCID) – pegademase bovine
  • Treatment for wet age-related macular degeneration (AMD) – pegaptanib ophthalmic
  • Treatment for cancer – pegaspargase
  • To reduce infection in patients receiving chemotherapy – pegfilgrastim
  • Treatment for hepatitis C and hepatitis B – peginterferon alfa-2a/alfa-2b
  • Treatment for acromegaly – pegvisomant

This list is not exhaustive and other drugs may interact with Krystexxa.

Krystexxa warning and precautions

You should not use Krystexxa if you:

  • Are allergic to the active ingredient pegloticase
  • Are allergic to any of the other ingredients in Krystexxa
  • Have G6PD (glucose-6-phosphate dehydrogenase deficiency)

Talk to your doctor before using Krystexxa if you:

  • Are taking any of the medications that could interact with Krystexxa
  • Have any heart problems or high blood pressure (hypertension)
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Related medications

Related conditions

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.