Lucemyra Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Lucemyra cost savings if eligible

If you are eligible for the Lucemyra patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Lucemyra through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Lucemyra patient assistance program?

You could receive your Lucemyra without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Lucemyra patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Lucemyra.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Lucemyra patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Lucemyra medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Lucemyra coupons provider?

At NiceRx, we help eligible individuals access the Lucemyra patient assistance program. This means that we are not a Lucemyra coupon, a Lucemyra discount card, or a Lucemyra copay card provider. We do not offer any medication trial offers, or free Lucemyra samples.

Can NiceRx help me get Lucemyra if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Lucemyra medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Lucemyra cost without insurance?

Lucemyra costs without insurance will vary depending on US WorldMeds, LLC and the retailer you buy it from. As a guide, Lucemyra oral tablet 0.18 mg will typically cost around $787 for 36 tablets. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Lucemyra cost with insurance?

The copay of Lucemyra will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Lucemyra?

Lucemyra is an FDA (Food and drug administration) approved medication manufactured by US WorldMeds, LLC for patients above 18 years of age, used to help in the mitigation of opioid withdrawal symptoms that may happen when patients stop taking an opioid suddenly (abrupt opioid discontinuation). Lucemyra will not completely prevent the symptoms of opioid withdrawal and is not a treatment for opioid use disorder (OUD).

Lucemyra is a central alpha-2 adrenergic agonist. Its mechanism of action is to decrease the release of norepinephrine by binding to receptors on adrenergic neurons. This reduces the neurochemical surge that produces withdrawal symptoms.

Symptoms of opioid withdrawal include:

  • Aches and pains
  • Stomach cramps
  • Feeling sick
  • Muscle spasms/twitching
  • Insomnia/problems sleeping
  • A feeling of coldness/chills
  • Muscular tension
  • Heart pounding
  • Runny eyes
  • Yawning

What doses of Lucemyra are available?

Lucemyra is available in 0.18mg oral tablet form.

The usual Lucemyra dosage is three 0.18 mg tablets (0.54mg) taken orally 4 times daily at 5- to 6-hour intervals. Lucemyra treatment may be continued for up to 14 days with dosing guided by symptoms.

Lucemyra use is discontinued by gradual dose reduction over 2 to 4 days.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Lucemyra active ingredients

Lucemyra is available as round, peach-colored, film-coated tablets, imprinted with “LFX” on one side and “18” on the other side. Each tablet contains 0.18 mg lofexidine (equivalent to 0.2 mg of lofexidine hydrochloride).

Lucemyra side effects

The most common side effects/adverse effects caused by Lucemyra include:

  • Hypotension (low blood pressure) symptoms such as lightheadedness
  • Bradycardia (slow heart rate)
  • Syncope (fainting or passing out)
  • Long QT Syndrome (heart rhythm condition)
  • Central Nervous System Depression
  • Opioid Overdose
  • Discontinuation Symptoms
  • Sleepiness or drowsiness
  • Dry mouth

In rare instances, Lucemyra can cause more serious side effects. These can include:

  • Ringing in the ears
  • Severe allergic reaction

If your experience any adverse effects, you should contact your healthcare provider immediately.

Your doctor will assess the benefits of using Lucemyra against your risk of side effects.

Patients are encouraged to report negative side effects or adverse reactions of Lucemyra to the FDA. Visit, or call 1-800-FDA-1088.

Lucemyra drug interactions

Lucemyra can interact with other medications. These include:

  • Methadone: Methadone and Lucemyra both prolong the QT interval. ECG monitoring is recommended when used concomitantly
  • Oral Naltrexone: Concomitant use may reduce the efficacy of oral naltrexone
  • CYP2D6 Inhibitors: Concomitant use of paroxetine resulted in increased
    plasma levels of Lucemyra. Monitor for symptoms of orthostasis
    and bradycardia with concomitant use of a CYP2D6 inhibitor

This list is not exhaustive and other drugs may interact with Lucemyra.

Lucemyra contraindications

You should not use Lucemyra if you:

  • Are allergic to the active ingredient Lucemyra

Talk to your doctor before using Lucemyra if you:

  • Take any medications or herbal supplements that could interact with Lucemyra
  • Take benzodiazepines, barbiturates, tranquilizers, or sleeping pills. Taking lofexidine with these medicines can cause serious side effects
  • Have low blood pressure
  • Have a slow heart rate
  • Have any heart problems, including a history of heart attacks or a condition called long QT syndrome
  • Have liver or kidney problems
  • Drink alcohol
  • Are pregnant or plan to become pregnant. It is not known if lofexidine can harm your unborn baby
  • Are breastfeeding or plan to breastfeed. It is not known if lofexidine passes into your breast milk

Lucemyra generic

Lucemyra is the trademark brand name for lofexidine manufactured by US WorldMeds, LLC. A generic version of Lucemyra is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Lucemyra savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.