Lupkynis Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Lupkynis cost savings if eligible

If you are eligible to receive your Lupkynis prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Lupkynis patient assistance?

To be eligible for the Lupkynis patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Lupkynis enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Lupkynis patient assistance program?

Applying for the Lupkynis patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Lupkynis, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Lupkynis assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Lupkynis patient assistance program, we will also request your Lupkynis medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx a Lupkynis coupons provider?

NiceRx does not provide Lupkynis coupons, discount cards, or copay cards. We do not offer printable Lupkynis manufacturer coupons, Lupkynis discounts, rebates, Lupkynis savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Lupkynis medication with NiceRx.

Can NiceRx help me get Lupkynis if I have insurance?

NiceRx may be able to help you access Lupkynis patient assistance if:

  • You have a high copay or coinsurance responsibility for Lupkynis
  • Your insurance company will not pay for your Lupkynis prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Lupkynis cost without insurance?

Lupkynis prices without insurance will vary by retailer. As a guide, Lupkynis oral capsules 7.9 mg will typically cost around $12,400 for a supply of 180 capsules.

How much does Lupkynis cost with insurance?

Your individual healthcare plan will determine the copay of Lupkynis with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Lupkynis?

Lupkynis is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Aurinia Pharmaceuticals Inc. It is a calcineurin-inhibitor immunosuppressant used in combination with a background immunosuppressive therapy regimen to treat adult patients with active lupus nephritis (LN). Lupus nephritis is a serious progression of systemic lupus erythematosus (SLE), a chronic, and complex autoimmune disease.

The safety and efficacy of Lupkynis have not been determined in combination with cyclophosphamide.

What doses of Lupkynis are available?

Lupkynis is available in capsule form, in the following doses: 7.9 mg.

Lupkynis is a capsule taken orally twice daily, on an empty stomach, at least 1 hour before or 2 hours after food. It is taken in combination with two other drugs (mycophenolate mofetil (MMF) and a corticosteroid). The capsule should be swallowed whole, do not crush, chew, break, or open it.

Voclosporin will affect your immune system. You may have an increased risk of infections, even serious or fatal infections. You will need regular medical tests while taking this medication.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition. Please see the prescribing information, including Boxed Warning, and the medication guide for Lupkynis.

Lupkynis active ingredients

Lupkynis contains the active ingredient voclosporin. The exact mechanism of action of voclosporin is not fully understood.

Lupkynis side effects

The most common side effects of Lupkynis in clinical trials include:

  • Decreased glomerular filtration rate
  • Diarrhea
  • Headache
  • Anemia
  • Cough
  • Urinary tract infection
  • Abdominal pain upper, loss of appetite
  • Dyspepsia
  • Alopecia
  • Renal impairment
  • Mouth ulceration
  • Fatigue
  • Tremor
  • Acute kidney injury

In rare instances, Lupkynis can cause more serious adverse events. These can include:

  • Nephrotoxicity, acute kidney injury – monitor renal function
  • Hypertension (high blood pressure)
  • Neurotoxicity
  • Hyperkalemia – monitor potassium levels
  • QT Prolongation
  • Pure Red Cell Aplasia – consider discontinuation of treatment

Your doctor will assess the benefits of using Lupkynis against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Lupkynis to the FDA. Visit, or call 1-800-FDA-1088.

Lupkynis drug interactions

Lupkynis can interact with other medications. These include:

  • Strong CYP3A4 inhibitors – ketoconazole, itraconazole, clarithromycin
  • Strong and moderate CYP3A4 inducers
  • Certain P-GP substrates
  • Live vaccines – avoid

This list is not exhaustive and other prescription drugs may interact with Lupkynis.

Lupkynis contraindications

You should not use Lupkynis if you:

  • Are allergic to the active ingredient voclosporin
  • Are allergic to any of the other ingredients in Lupkynis
  • Are pregnant or are planning to become pregnant – There are risks (eg, worsening of the underlying disease, premature birth, miscarriage, intrauterine growth restriction) to mother and fetus associated with systemic lupus erythematosus (SLE)
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Lupkynis if you:

  • Are taking any of the medications that could interact with Lupkynis
  • Have renal Impairment – Lupkynis is not recommended in patients with a baseline eGFR ≤45 mL/min/1.73 m2 unless the benefit exceeds the risk. If used in patients with severe renal impairment at baseline, Lupkynis should be used at a reduced dose
  • Have mild and moderate hepatic impairment – reduce the dose. Avoid use for severe hepatic impairment

Lupkynis generic

Lupkynis is the trademark brand name for voclosporin manufactured by Aurinia Pharmaceuticals Inc. A generic version of voclosporin is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Lupkynis savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.