Luxturna Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Luxturna cost savings if eligible

If you are eligible for the Luxturna patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Luxturna through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Luxturna patient assistance program?

You could receive your Luxturna without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for Luxturna patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Luxturna.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Luxturna patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Luxturna medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Luxturna coupons provider?

At NiceRx, we help eligible individuals access the Luxturna patient assistance program. This means that we are not a Luxturna coupon, a Luxturna discount card, or a Luxturna copay card provider. We do not offer any medication trial offers, or free Luxturna samples.

Can NiceRx help me get Luxturna if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Luxturna medication, or you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Luxturna cost without insurance?

Luxturna costs without insurance will vary depending on the retailer you buy it from. As a guide, Luxturna will typically cost around $425,000 per eye. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Luxturna cost with insurance?

The copay of Luxturna will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Luxturna?

Luxturna is an FDA (U.S. Food and Drug Administration) approved medication developed by Spark Therapeutics Inc. and Children’s Hospital of Philadelphia.

It is an adeno-associated virus vector-based gene therapy indicated for the treatment of patients with confirmed biallelic RPE65 mutation-associated inherited retinal dystrophy that leads to vision loss and may cause complete blindness in certain patients.

Inherited retinal diseases are a group of eye disorders characterized by the degeneration of different parts of the retina. It is caused by more than 250 different genes, often affecting children and young adults. Mutations in both copies of the RPE65 gene affect approximately 1 in 200,000 people.

Early in the disease patients can suffer from night blindness, loss of light sensitivity, peripheral vision, sharpness or clarity of vision, impaired dark adaptation, and repetitive uncontrolled movements of the eye. Patients with mutations in both copies of the RPE65 gene may be diagnosed, for instance, with subtypes of either Leber congenital amaurosis or retinitis pigmentosa. A genetic test is needed to confirm that vision loss is caused by mutations in the RPE65 gene.

Luxturna can only be used while patients still have sufficient viable retinal cells functioning in the retina and when the disease is caused by mutations in the RPE65 gene. RPE65 is responsible for the production of an enzyme called all-trans retinyl isomerase, which is needed for the normal functioning of retinal cells. Patients must have viable retinal cells as determined by the treating physician

Luxturna consists of a virus that contains normal copies of the RPE65 gene. When Luxturna is injected into the eye the virus carries the RPE65 gene into the retinal cells enabling them to produce the missing enzyme. This helps the cells in the retina to function better, slowing down the progression of the disease. The adeno-associated virus used in Luxturna does not cause disease in humans.

The efficacy of Luxturna was established based on the multi-luminance mobility test (MLMT) score change from baseline to one year. MLMT was designed to measure changes in functional vision as assessed by the ability of a patient to navigate a course accurately and at a reasonable pace at seven different light levels, ranging from 400 lux (corresponding to a brightly lit office) to one lux (corresponding to a moonless summer night).

What doses of Luxturna are available?

Luxturna is available as a subretinal injection suspension, in the following doses: 0.5 mL extractable volume in a single-dose 2 mL vial for a single administration in one eye. The supplied concentration (5x1012vg/mL) requires a 1:10 dilution before administration.

The recommended dose for each eye is 1.5 x 1011 vector genomes, administered by subretinal injection in a total volume of 0.3 mL.

Perform subretinal administration of Luxturna to each eye on separate days, but no fewer than 6 days apart. Systemic oral corticosteroids starting 3 days before administration of Luxturna to each eye, and continuing for another 7 days after is advised.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Luxturna active ingredients

Luxturna contains voretigene neparvovec-rzyl as the active ingredient.

Luxturna side effects

The most common side effects of Luxturna in clinical trials include:

  • Conjunctival hyperemia
  • Cataract
  • Increased intraocular pressure
  • Retinal tear
  • Thinning of the corneal stroma
  • Macular hole
  • Subretinal deposits
  • Eye inflammation, irritation, and pain
  • Maculopathy

In rare instances, Luxturna can cause more serious side effects. These can include:

  • Endophthalmitis
  • Permanent decline in visual acuity
  • Retinal abnormalities
  • Expansion of intraocular air bubbles – air travel and/or scuba diving is not recommended until any intraocular air bubbles have been absorbed

Your doctor will assess the benefits of using Luxturna against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Luxturna to the FDA. Visit, or call 1-800-FDA-1088.

Luxturna drug interactions

There is currently no data for Luxturna interactions with other medications. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Luxturna contraindications

You should not use Luxturna if you:

  • Are allergic to the active ingredient voretigene neparvovec-rzyl
  • Are allergic to any of the other ingredients in Luxturna
  • Are younger than 12 months of age or older than 65 years of age

Talk to your doctor before using Luxturna if you:

  • Are taking any of the medications that could interact with Luxturna
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Luxturna generic

Luxturna is the trademark brand name for voretigene neparvovec-rzyl manufactured by Spark Therapeutics, Inc. A generic version of voretigene neparvovec-rzyl is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Luxturna savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.