Menostar Coupon & Prices

Is your Menostar medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Menostar medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Menostar cost savings if eligible

The Menostar patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Menostar, regardless of the retail price.

Am I eligible for the Menostar patient assistance program?

To find out if you are eligible for Menostar assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Menostar patient assistance program?

Our application process aims to make it as easy as possible to apply for the Menostar patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Menostar.

NiceRx will review your application and determine whether you may be eligible for Menostar assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Menostar patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Menostar.

Is NiceRx a Menostar coupon provider?

NiceRx is a service provider that helps eligible individuals access the Menostar patient assistance program. We do not offer trial offers or free Menostar samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Menostar coupons, discount cards, or Menostar copay cards.

Can NiceRx help me get Menostar cheaper if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Menostar medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Menostar cost without insurance?

Menostar prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Menostar transdermal film, extended-release (14 mcg/24 hours weekly) typically costs $180 for a supply of 4 films.

How much does Menostar cost with insurance?

The copay for Menostar will vary by the terms of your healthcare plan. To find out what you might need to pay for Menostar with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Menostar?

Menostar (estradiol transdermal system) is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Bayer. Menostar is classed as an estrogen derivative. It may be used alone or in combination with other medicines for:

  • The prevention of postmenopausal osteoporosis
  • Symptoms of vulvar and vaginal atrophy in menopause
  • Hypoestrogenism from castration
  • Hypogonadism
  • Ovarian failure
  • Metastatic breast cancer
  • Hypoestrogenism
  • Prostate cancer
  • Vasomotor symptoms associated with menopause

There is an increased risk of endometrial cancer in a woman with a uterus who uses unopposed estrogens. Estrogen-alone therapy should not be used for the prevention of cardiovascular disease or dementia. The Women’s Health Initiative (WHI) estrogen-alone substudy reported increased risks of stroke and deep vein thrombosis (DVT), and an increased risk of probable dementia in postmenopausal women 65 years of age and older.

Estrogen plus progestin therapy should not be used for the prevention of cardiovascular disease or dementia. The WHI estrogen plus progestin substudy reported increased risks of stroke, DVT, pulmonary embolism (PE), and myocardial infarction, increased risks of invasive breast cancer, and an increased risk of probable dementia in postmenopausal women 65 years of age and older.

What doses of Menostar are available?

Menostar is available as a transdermal system, in the following doses: 14 mcg per day.

Apply the Menostar patch once-weekly to the lower abdomen. Menostar should not be applied to the breast. Please read the patient information leaflet and always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Menostar active ingredients

Menostar contains estradiol as the active ingredient.

Menostar side effects

The most common side effects of Menostar in clinical trials include:

  • Upper respiratory tract infections
  • Vaginal discharge
  • Breast pain
  • Headache, back pain, arthralgia
  • Stuffy nose, sinus pain, sore throat
  • Bloating, stomach cramps, nausea, vomiting
  • Application site reaction
  • Hair loss
  • Fluid retention

In rare instances, Menostar can cause more serious side effects. These can include:

  • Increased risk of gallbladder disease
  • Severe hypertriglyceridemia or cholestatic jaundice (estrogen therapy may be associated with elevations of plasma triglyceride levels leading to pancreatitis) – monitor thyroid function in women on thyroid hormone replacement therapy
  • Increased risk of breast cancer, breast lump
  • Symptoms of heart attack – chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating
  • Increased blood pressure – severe headache, blurred vision, pounding in your neck or ears, anxiety, hot flashes, nosebleed
  • Stroke – sudden numbness or weakness on one side of the body, sudden severe headache, slurred speech, problems with vision or balance
  • Blood clots – sudden vision loss, sharp chest pain, shortness of breath, coughing up blood, pain or warmth in one or both legs
  • Jaundice (yellowing of the skin or eyes)
  • Unusual vaginal bleeding, pelvic pain
  • Confusion, unusual behavior, problems with memory
  • Increased blood calcium levels – nausea, vomiting, constipation, increased thirst or urination, muscle weakness, bone pain, lack of energy
  • Edema, tiredness, menopausal symptoms, increased weight

Your doctor will assess the benefits of using Menostar against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Menostar to the FDA. Visit, or call 1-800-FDA-1088.

Menostar drug interactions

Menostar can interact with other medications. These include:

  • Inducers of CYP3A4 – St John’s wort, phenobarbital, carbamazepine, and rifampin
  • Inhibitors of CYP3A4 – erythromycin, clarithromycin, ketoconazole, itraconazole, ritonavir, and grapefruit juice

This list is not exhaustive and other prescription drugs may interact with Menostar. Tell your healthcare provider about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Menostar contraindications

You should not use Menostar if you:

  • Are allergic to the active ingredient estradiol
  • Have had an allergic reaction or angioedema to any of the other ingredients in Menostar
  • Have an active DVT, PE or a history of these conditions
  • Have undiagnosed unusual vaginal bleeding
  • Have liver disease
  • Have a history of heart attack or stroke
  • Have a history of hormone-dependent cancer (such as breast, uterine, ovarian, or thyroid cancer)
  • Have ever had a blood clot
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Menostar if you:

  • Are taking any of the medications that could interact with Menostar
  • Have heart disease
  • Have risk factors for coronary artery disease such as diabetes, lupus, smoking, being overweight, having high blood pressure or high cholesterol, having a family history of coronary artery disease, or if you have had a hysterectomy
  • Have a history of jaundice caused by pregnancy or birth control pills
  • Have hereditary angioedema
  • Have a thyroid disorder
  • Have kidney disease
  • Have asthma
  • Have epilepsy or other seizure disorder
  • Suffer from migraines
  • Have porphyria
  • Have endometriosis or uterine fibroid tumors
  • Have gallbladder disease
  • Have had a hysterectomy
  • Are breastfeeding or are planning to breastfeed – Estrogen has been shown to decrease the quantity and quality of breast milk

Menostar generic

Menostar is the trademark brand name for estradiol manufactured by Bayer. A generic version of estradiol is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Menostar savings through NiceRx.

Related conditions

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability and acceptance by the pharmaceutical companies. NiceRx is not responsible for any delays or rejection by the pharmaceutical companies.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.