Neoprofen Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly NeoProfen cost savings if eligible

If you are eligible for the NeoProfen patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your NeoProfen prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the NeoProfen patient assistance program?

We will review your application to determine whether you are eligible for the NeoProfen patient assistance program. Each program has its own eligibility criteria which is set by the pharmaceutical companies, however the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the NeoProfen patient assistance program?

We make it as easy as possible to apply for the NeoProfen patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including NeoProfen. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for NeoProfen assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the NeoProfen patient assistance program, and we will automatically request your NeoProfen medication refills for up to 1 year.

Is NiceRx a NeoProfen coupon provider?

We are a service provider that helps eligible individuals access the NeoProfen patient assistance program. That means that we do not offer printable NeoProfen manufacturer coupons, NeoProfen discounts, or free NeoProfen samples. We are not a NeoProfen coupon provider or NeoProfen discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get NeoProfen cheaper if I have insurance?

We may be able to help you to access NeoProfen patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your NeoProfen medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does NeoProfen cost without insurance?

NeoProfen cost without insurance will vary depending on where you buy it. As a guide, NeoProfen intravenous solution (10 mg/mL) usually costs $3,100 for 6 milliliters. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does NeoProfen cost with insurance?

The copay for NeoProfen with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is NeoProfen?

NeoProfen (Ibuprofen lysine) is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Recordati Rare Diseases. NeoProfen is used to close a clinically significant patent ductus arteriosus (PDA) in premature infants that weigh between 0.5 kg and 1.5 kg, who are no more than 32 weeks gestational age when usual medical management is not effective.

Treatment is for infants with clear evidence of a clinically significant PDA, as the results of treatment after 8 weeks have not been ascertained.

What doses of NeoProfen are available?

NeoProfen is available as a clear sterile preservative-free solution, in the following doses: 10 mg/mL of the L-lysine salt of ibuprofen in a 2 mL single-use vial.

Please read the full drug information and always speak with your healthcare provider for medical advice about any changes to your dose so they can monitor and evaluate your condition.

NeoProfen active ingredients

NeoProfen contains ibuprofen lysine, a nonsteroidal anti-inflammatory drug (NSAID), as the active ingredient.

NeoProfen side effects

The most common side effects of NeoProfen in clinical trials include:

  • Sepsis
  • Intraventricular bleeding
  • Apnea
  • Gastrointestinal disorders
  • Impaired renal function
  • Respiratory infection, skin lesions, hypoglycemia, hypocalcemia
  • Respiratory failure
  • Skin lesions
  • Hypoglycemia (low blood sugar)
  • Hypocalcemia (low calcium)

In rare instances, NeoProfen can cause more serious side effects. These can include:

  • Changes in vision
  • Feeling short of breath, rapid weight gain
  • Difficulty urinating
  • Chest pains, irregular heartbeats
  • Loss of appetite, stomach pain, dark urine, jaundice (yellowing of the skin or eyes)
  • Low red blood cells (anemia)
  • Bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds
  • Signs of infection
  • Prolonged bleeding due to inhibition of platelets

Your doctor will assess the benefits of using NeoProfen against your risk of side effects. Patients are encouraged to report negative side effects or adverse events of NeoProfen to the FDA. Visit, or call 1-800-FDA-1088.

NeoProfen drug interactions

NeoProfen can interact with other medications. These include:

  • Blood thinners such as warfarin
  • Treatments for heart or blood pressure
  • Diuretics
  • Steroid treatments such as prednisolone

This list is not exhaustive and other prescription drugs may interact with NeoProfen.

NeoProfen contraindications

You should not use NeoProfen if you:

  • Are allergic to the active ingredient Ibuprofen lysine
  • Have had an allergic reaction to any of the other ingredients in NeoProfen
  • NeoProfen is contraindicated in preterm infants with: or suspected untreated infection, congenital heart disease in whom patency of the PDA is necessary for satisfactory pulmonary or systemic blood flow, renal impairment, thrombocytopenia, coagulation defects, or who are bleeding, or who are suspected of having necrotizing enterocolitis

Talk to your doctor before using NeoProfen if you:

  • Are taking any of the medications that could interact with NeoProfen
  • Have had a heart attack, stroke, or blood clot
  • Have stomach ulcers or bleeding
  • Have asthma
  • Have liver or kidney disease
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

NeoProfen generic

NeoProfen is the trademark brand name for Ibuprofen lysine manufactured by Recordati Rare Diseases. A generic version of Ibuprofen lysine is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find NeoProfen savings through NiceRx.

Related conditions

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.