Nexviazyme Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a Nexviazyme coupon provider?

At NiceRx, we help eligible individuals access patient assistance programs. This means that we are not a Nexviazyme coupon, a Nexviazyme discount card, or a Nexviazyme copay card provider. We do not offer any medication trial offers or free Nexviazyme samples.

Nexviazyme patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

Can NiceRx help me get Nexviazyme cheaper if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Nexviazyme medication, or if you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Nexviazyme cost without insurance?

Nexviazyme costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Nexviazyme intravenous injection of 100 mg will typically cost around $1,800 for 1 injection.

How much does Nexviazyme cost with insurance?

The copay of Nexviazyme will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Nexviazyme?

Nexviazyme is an FDA (U.S. Food and Drug Administration) approved medication manufactured by the Sanofi Genzyme Corporation. Nexviazyme is a hydrolytic lysosomal glycogen-specific enzyme used to treat patients 1 year of age and older with late-onset Pompe disease, LOPD (lysosomal acid alpha-glucosidase [GAA] deficiency). An earlier enzyme replacement therapy (ERT), alglucosidase alfa, (also made by Sanofi Genzyme) was approved in 2006 for infantile-onset Pompe disease (IOPD).

What doses of Nexviazyme are available?

Nexviazyme is available in injection form, in the following doses: 100 mg.

Administer antihistamines, antipyretics, and/or corticosteroids before Nexviazyme administration to reduce the risk of Infusion-Associated Reactions (IARs). Nexviazyme is given as an intravenous infusion. For patients weighing 30 kg or more, the recommended dose is 20 mg/kg every two weeks. For patients weighing less than 30 kg, the recommended dose is 40 mg/kg every two weeks.

Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Nexviazyme active ingredients

Nexviazyme contains avalglucosidase alfa-ngpt, an enzyme replacement therapy (ERT) designed to target the mannose-6-phosphate receptor, the main process for cellular uptake of ERT in Pompe disease.

Nexviazyme side effects

The most common side effects of Nexviazyme in clinical trials include:

  • Headache, dizziness
  • Fatigue
  • Diarrhea, nausea, vomiting
  • Arthralgia, myalgia
  • Pruritus
  • Dyspnea
  • Erythema
  • Paresthesia
  • Urticaria

In rare instances, Luxiq can cause more serious side effects. These can include:

  • Severe hypersensitivity reactions, including anaphylaxis
  • Infusion associated reactions
  • Risk of acute cardiorespiratory failure – those at risk of fluid volume overload, or those with acute underlying respiratory illness or problems with cardiac or respiratory function, may be at risk of seriously worsening their cardiac or respiratory function during Nexviazyme infusion

Your doctor will assess the benefits of using Nexviazyme against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Nexviazyme to the FDA. Visit, or call 1-800-FDA-1088.

Nexviazyme drug interactions

Other drugs may interact with Nexviazyme, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medications including any supplements you are taking.

Nexviazyme contraindications

You should not use Nexviazyme if you:

  • Are allergic to the active ingredient avalglucosidase alfa-ngpt
  • Are allergic to any of the other ingredients in Nexviazyme

Talk to your doctor before using Nexviazyme if you:

  • Are taking any of the medications that could interact with Nexviazyme
  • Have heart disease
  • Have lung disease or breathing problems
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Nexviazyme generic

Nexviazyme is the trademark brand name for avalglucosidase alfa-ngpt manufactured by Sanofi Genzyme. A generic version of avalglucosidase alfa-ngpt is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Nexviazyme savings through NiceRx.

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The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.