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Ocaliva Patient assistance program

Is your Ocaliva medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Ocaliva medication.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
  • Next steps after qualifying
  • Uploading documents and billing
  • SSN & billing information
  • Medication delivery time

How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Your monthly Ocaliva cost savings if eligible

With our assistance, you could access the Ocaliva patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Ocaliva patient assistance?

We review each Ocaliva enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Ocaliva patient assistance program?

Our process makes it as easy as possible to apply for the Ocaliva patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Ocaliva, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx an Ocaliva coupons provider?

NiceRx is not an Ocaliva coupon, Ocaliva discount card, or Ocaliva copay card provider. We do not offer Ocaliva manufacturer coupons, Ocaliva discounts, rebates, Ocaliva savings cards, trial offers, or free Ocaliva samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Ocaliva
  • Your insurance company will not pay for your Ocaliva prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Ocaliva cost without insurance?

Without insurance, Ocaliva costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Ocaliva oral tablets 5 mg will cost around $7,950 for 30 tablets.

How much does Ocaliva cost with insurance?

The copay for Ocaliva will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Ocaliva?

Ocaliva is an FDA (U.S. Food and Drug Administration) approved medication manufactured by New York-based Intercept Pharmaceuticals, Inc. This use is approved by the FDA under accelerated approval based on a reduction in alkaline phosphatase (ALP).

Ocaliva is a farnesoid X receptor (FXR) agonist and is used to treat primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with an inadequate response to UDCA, or as monotherapy in adults unable to tolerate UDCA.


  • In postmarketing reports, hepatic decompensation and failure, in some cases fatal, have been reported in patients with primary biliary cholangitis (PBC) with decompensated cirrhosis or Child-Pugh Class B or C hepatic impairment, when Ocaliva was given more frequently than recommended
  • The recommended starting dosage of Ocaliva is 5 mg once weekly for patients with Child-Pugh Class B or C hepatic impairment or a prior decompensation event

What doses of Ocaliva are available?

Ocaliva is available in tablet form, in the following doses: 5 mg, 10 mg.

Always speak with your healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Ocaliva active ingredients

The active ingredient of Ocaliva is obeticholic acid.

Ocaliva side effects

The most common side effects of Ocaliva in clinical trials include:

  • Pruritus (itching), rash, eczema
  • Tiredness
  • Abdominal pain and discomfort
  • Loss of appetite, constipation
  • Oropharyngeal pain
  • Dizziness
  • Arthralgia (joint pain)
  • Thyroid function abnormality

In rare instances, Ocaliva can cause more serious side effects. These can include:

  • Worsening liver problems or liver failure – nausea, vomiting, diarrhea, jaundice (yellowing of skin and eyes), scleral icterus, and/or dark urine. Monitor liver function. Dosage adjustments, interruption, or discontinuation may be required. Discontinue in patients who develop complete biliary obstruction
  • Severe pruritus – use bile acid-binding resins or antihistamines, dose reduction, and/or temporary dosing interruption
  • Reduction in HDL-C – monitor serum lipid levels during treatment

Your doctor will assess the benefits of using Ocaliva against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Ocaliva to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Ocaliva drug interactions

Ocaliva can interact with other medications. These include:

  • Warfarin – potential decreased INR, monitor, and adjust the dosage as needed, to maintain the target INR range
  • CYP1A2 substrates with narrow therapeutic index – theophylline, tizanidine
  • Inhibitors of bile salt Efflux pump – cyclosporine

This list is not exhaustive and other prescription drugs may interact with Ocaliva.

Ocaliva contraindications

You should not use Ocaliva if you:

  • Are allergic to the active ingredient obeticholic acid
  • Are allergic to any of the other ingredients in Ocaliva
  • Are pregnant or are planning to become pregnant
  • Have complete biliary obstruction

Talk to your doctor before using Ocaliva if you:

  • Are taking any of the medications that could interact with Ocaliva
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed
  • Have hepatic impairment (liver disease)

Ocaliva generic

Ocaliva is the trademark brand name for obeticholic acid manufactured by Intercept Pharmaceuticals, Inc. A generic version of obeticholic acid is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Ocaliva savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.