Oncaspar Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Oncaspar cost savings if eligible

The Oncaspar patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Oncaspar, regardless of the retail price.

Am I eligible for the Oncaspar patient assistance program?

To find out if you are eligible for Oncaspar assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Oncaspar patient assistance program?

Our application process aims to make it as easy as possible to apply for the Oncaspar patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Oncaspar.

NiceRx will review your application and determine whether you may be eligible for Oncaspar assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Oncaspar patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Oncaspar.

Is NiceRx an Oncaspar coupon provider?

NiceRx is a service provider that helps eligible individuals access the Oncaspar patient assistance program. We do not offer trial offers or free Oncaspar samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Oncaspar coupons, discount cards, or Oncaspar copay cards.

Can NiceRx help me get Oncaspar cheaper if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Oncaspar medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Oncaspar cost without insurance?

Oncaspar prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Oncaspar injectable solution (750 intl units/mL) typically costs $23,400 for 5 milliliters.

How much does Oncaspar cost with insurance?

The copay for Oncaspar will vary by the terms of your healthcare plan. To find out what you might need to pay for Oncaspar with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Oncaspar?

Oncaspar is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Servier Pharmaceuticals. Oncaspar is an asparagine specific enzyme indicated as a component of a multi-agent chemotherapeutic regimen for the:

  • First-line treatment of acute lymphoblastic leukemia
  • Treatment of acute lymphoblastic leukemia and hypersensitivity to asparaginase

What doses of Oncaspar are available?

Oncaspar is available in injection form, in the following doses: 3,750 International Units/5 mL solution in a single-use vial.

Administer 2,500 International Units/m2 intramuscularly or intravenously no more frequently than every 14 days. For intramuscular administration, limit the volume at a single injection site to 2 mL. If greater than 2 mL, use multiple injection sites.

For intravenous administration, give over a period of 1 to 2 hours in 100 mL of sodium chloride or dextrose injection 5%, through an infusion that is already running. Do not administer Oncaspar if the drug has been frozen, stored at room temperature for more than 48 hours, or shaken or vigorously agitated.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Oncaspar active ingredients

L-asparaginase is an enzyme that catalyzes the conversion of the amino acid L-asparagine into aspartic acid and ammonia. Oncaspar is thought to work by killing leukemic cells due to asparagine depletion. Leukemic cells with low expression of asparagine synthetase have a reduced ability to synthesize asparagine and therefore depend on an exogenous source of asparagine for survival.

Oncaspar side effects

The most common side effects of Oncaspar in clinical trials include:

  • Central nervous system (CNS) thrombosis
  • Elevated transaminases
  • Hyperbilirubinemia
  • Hyperglycemia (high blood sugar)
  • Pancreatitis – abdominal pain

In rare instances, Oncaspar can cause more serious side effects. These can include:

  • Anaphylaxis or serious allergic reactions
  • Thrombosis
  • Pancreatitis
  • Glucose intolerance, in some cases irreversible, can occur
  • Coagulopathy can occur. Perform appropriate monitoring
  • Hepatotoxicity (liver toxicity) and abnormal liver function including elevations of AST (SGOT), ALT (SGPT), alkaline phosphatase, bilirubin, and depression of serum albumin, and plasma fibrinogen
  • Get medical help right away if any of these rare but very serious side effects occur – sudden shortness of breath, chest pain, severe headache, seizures, difficulty speaking, confusion, vision changes, and weakness on one side of the body.

Your doctor will assess the benefits of using Oncaspar against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Oncaspar to the FDA. Visit, or call 1-800-FDA-1088.

Oncaspar drug interactions

Other drugs may interact with Oncaspar, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medicines including any supplements you are taking.

Oncaspar contraindications

You should not use Oncaspar if you:

  • Are allergic to the active ingredient pegaspargase
  • Have had previous hypersensitivity reactions to any of the other ingredients in Oncaspar
  • Have had serious blood clots, serious swelling of the pancreas, or serious bleeding during previous L-asparaginase treatment
  • Have serious impairment of liver function
  • Are pregnant or are planning to become pregnant – Use effective contraception to prevent pregnancy while you are using this medicine and for at least 3 months after your last dose

Talk to your doctor before using Oncaspar if you:

  • Are taking any of the medications that could interact with Oncaspar
  • Have liver problems
  • Have diabetes
  • Are breastfeeding or are planning to breastfeed

Oncaspar generic

Oncaspar is the trademark brand name for pegaspargase manufactured by Servier Pharmaceuticals. A generic version of pegaspargase is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Oncaspar savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.