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Ongentys Patient assistance program

Is your Ongentys medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Ongentys medication.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
    (01:52)
  • Next steps after qualifying
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  • Uploading documents and billing
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  • SSN & billing information
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  • Medication delivery time
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How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Your monthly Ongentys cost savings if eligible

With our assistance, you could access the Ongentys patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Ongentys patient assistance?

We review each Ongentys enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Ongentys patient assistance program?

Our process makes it as easy as possible to apply for the Ongentys patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Ongentys, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx an Ongentys coupons provider?

NiceRx is not an Ongentys coupon, Ongentys discount card, or Ongentys copay card provider. We do not offer Ongentys manufacturer coupons, Ongentys discounts, rebates, Ongentys savings cards, trial offers, or free Ongentys samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Ongentys
  • Your insurance company will not pay for your Ongentys prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Ongentys cost without insurance?

Without insurance, Ongentys costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Ongentys oral capsule 25 mg will cost around $625 for 30 capsules.

How much does Ongentys cost with insurance?

The copay for Ongentys will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Ongentys?

Ongentys is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Neurocrine Biosciences Inc. Ongentys is a catechol-O-methyltransferase (COMT) inhibitor used as adjunctive treatment to levodopa/carbidopa in patients with Parkinson’s disease (PD) experiencing “off” episodes or off time.

What doses of Ongentys are available?

Ongentys is available in capsule form, in the following doses: 25 mg and 50 mg.

The recommended dose is 50 mg orally once daily at bedtime. Patients should not eat food for 1 hour before and for at least 1 hour after taking Ongentys. The recommended dose in patients with moderate hepatic impairment is 25 mg orally once daily at bedtime. If a dose is missed, skip the missed dose and take the next dose at the regular time (the next day at bedtime).

Always speak with your healthcare provider for medical advice or about any changes to your dose so they can monitor and evaluate your condition.

Ongentys active ingredients

The active ingredient of Ongentys is opicapone, it is classed as a COMT inhibitor and is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).

Physiological substrates of COMT include DOPA, catecholamines (dopamine, norepinephrine, and epinephrine), and their hydroxylated metabolites. When decarboxylation of levodopa is prevented by carbidopa, COMT becomes the major metabolizing enzyme for levodopa.

Ongentys side effects

The most common side effects of Ongentys in clinical trials include:

  • Constipation
  • Increased blood creatine kinase
  • Hypotension (low blood pressure), lightheadedness
  • Syncope
  • Weight loss

In rare instances, Ongentys can cause more serious adverse effects. These can include:

  • Arrhythmias, increased heart rate
  • Drowsiness
  • Dyskinesia – consider levodopa or dopaminergic medication dose reduction
  • Hallucinations and psychosis
  • Impulse Control/Compulsive Disorders – sexual urges, unusual urges to gamble, binge eating, or other intense urges
  • Withdrawal-Emergent Hyperpyrexia and Confusion – when discontinuing Ongentys monitor patients and consider adjustment of other dopaminergic therapies

Your healthcare professional will assess the benefits of using Ongentys against your risk of possible side effects. Patients are encouraged to report negative side effects or adverse reactions of Ongentys to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Ongentys drug interactions

Ongentys can interact with other medications. These include:

  • MAO inhibitors such as isocarboxazid, linezolid, methylene blue injection, phenelzine, tranylcypromine

This list is not exhaustive and other prescription drugs may interact with Ongentys. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Ongentys contraindications

You should not use Ongentys if you:

  • Are allergic to the active ingredient opicapone
  • Are allergic to any of the other ingredients in Ongentys
  • Have pheochromocytoma (tumor of the adrenal gland)
  • Have paraganglioma (tumor of the nerve cells)
  • Have other catecholamine secreting neoplasms

Talk to your doctor before using Ongentys if you:

  • Are taking any of the medications that could interact with Ongentys
  • Are breastfeeding or are planning to breastfeed
  • Are taking non-selective monoamine oxidase (MAO) inhibitors
  • Are pregnant or are planning to become pregnant – may cause fetal harm
  • Have a sleep disorder that causes daytime sleepiness
  • Have uncontrolled muscle movements
  • Have liver disease
  • Have kidney disease

Ongentys generic

Ongentys is the trademark brand name for opicapone manufactured by Neurocrine Biosciences Inc. A generic version of opicapone is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Ongentys savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.