Onpattro Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Onpattro cost savings if eligible

With our assistance, you could access the Onpattro patient assistance program and obtain your medication for free. We only charge a flat monthly fee of $49 per medication for our services.

Am I eligible for Onpattro patient assistance?

We review each Onpattro enrollment application individually to determine if you are eligible. Each assistance program has its own eligibility criteria and the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Onpattro patient assistance program?

Our process makes it as easy as possible to apply for the Onpattro patient assistance program. Begin by completing the enrollment application form on our website. Tell us about any medications that you are taking, including Onpattro, your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers who will supply the medication, so it is important to make sure this information is accurate and up to date.

We will review the information that you have provided to determine whether you are eligible for patient assistance. If we can pre-qualify you for assistance, NiceRx will handle the full enrollment process on your behalf. If you are approved by the pharmaceutical company, you will typically start receiving your medication in 6 – 8 weeks.

Is NiceRx an Onpattro coupons provider?

NiceRx is not an Onpattro coupon, Onpattro discount card, or Onpattro copay card provider. We do not offer Onpattro manufacturer coupons, Onpattro discounts, rebates, Onpattro savings cards, trial

offers, or free Onpattro samples. We are a service provider that helps eligible individuals access their medication directly from the U.S. pharmaceutical company.

Can NiceRx help me if I have insurance?

NiceRx may be able to help you if:

  • You have a high copay or coinsurance responsibility for Onpattro
  • Your insurance company will not pay for your Onpattro prescription
  • Your healthcare plan does not cover your medication
  • You do not have insurance

Please apply online to find out if we can help you.

How much does Onpattro cost without insurance?

Without insurance, Onpattro costs will vary depending on where you buy the medication as prices will vary by retailer. As a guide, Onpattro intravenous solution (2 mg/mL) will cost around $9,930 for a supply of 5 milliliters.

How much does Onpattro cost with insurance?

The copay for Onpattro will depend on the terms of your healthcare plan. Your healthcare provider or pharmacist will be able to calculate your copay with your current insurance. Contact them to find out more.

What is Onpattro?

Onpattro has FDA approval (U.S. Food and Drug Administration) for the treatment of the polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR amyloidosis) in adults. It is manufactured by Alnylam Pharmaceuticals, Inc.

Onpattro contains a transthyretin-directed small interfering RNA that works by encasing siRNA in lipids and stops the production of disease-causing amyloid proteins.

What doses of Onpattro are available?

Onpattro is available as a Lipid Complex Injection in the following doses: 10 mg/5 mL (2 mg/mL) in a single-dose vial.

Onpattro doses are based on actual body weight. Your dose may need to change if you gain or lose weight. Onpattro treatment is given as an intravenous infusion into a vein. A healthcare provider will give you this injection once every 3 weeks. The infusion must be given slowly, it can take up to 80 minutes to complete.

You may need regular medical tests, even if you have no symptoms. Tests can help your doctor decide if this medicine is working. You may also need regular eye tests.

Always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Onpattro active ingredients

Patisiran is a double-stranded siRNA that causes degradation of mutant and wild-type TTR mRNA through RNA interference (RNAi). This results in a reduction of serum TTR protein and TTR protein deposits in tissues.

Onpattro side effects

The most common side effects of Onpattro in clinical trials include:

  • Upper respiratory tract infections

In rare instances, Onpattro can cause more serious side effects. These can include:

  • Infusion-related reactions – discontinue the infusion if a serious or life-threatening infusion-related reaction occurs. To reduce the risk of IRRs, patients should receive premedication with a corticosteroid (acetaminophen, dexamethasone) and antihistamines (H1 and H2 blockers such as diphenhydramine) at least 60 minutes before treatment begins
  • Reduced serum vitamin A levels – refer to an ophthalmologist if ocular symptoms suggestive of vitamin A deficiency occurs. If you have problems with your vision, such as night blindness, talk to your doctor. Your doctor will tell you to take a vitamin A supplement every day

Your doctor will assess the benefits of using Onpattro against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Onpattro to the FDA. Visit, or call 1-800-FDA-1088.

Onpattro drug interactions

Currently, there is no data regarding drug interactions with Onpattro however, tell your doctor about all your current medicines including prescription drugs and over-the-counter medicines, vitamins, and herbal products you start or stop using.

Onpattro contraindications

You should not use Onpattro if you:

  • Are allergic to the active ingredient patisiran
  • Are allergic to any of the other ingredients in Onpattro

Talk to your doctor before using Onpattro if you:

  • Are taking any of the medications that could interact with Onpattro
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed

Onpattro generic

Onpattro is the trademark brand name for patisiran manufactured by Alnylam Pharmaceuticals, Inc. A generic version of patisiran is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Onpattro savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.