Onureg Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Your monthly Onureg cost savings if eligible

The Onureg patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Onureg, regardless of the retail price.

Am I eligible for the Onureg patient assistance program?

To find out if you are eligible for Onureg assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Onureg patient assistance program?

Our application process aims to make it as easy as possible to apply for the Onureg patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Onureg.

NiceRx will review your application and determine whether you may be eligible for Onureg assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Onureg patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Onureg.

Is NiceRx an Onureg coupons provider?

NiceRx is a service provider that helps eligible individuals access the Onureg patient assistance program. We do not offer trial offers or free Onureg samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Onureg coupons, discount cards, or Onureg copay cards.

Can NiceRx help me get Onureg if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Onureg medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Onureg cost without insurance?

Onureg prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Onureg oral tablets 200mg typically cost $11,000 for 7 tablets.

How much does Onureg cost with insurance?

The copay for Onureg will vary by the terms of your healthcare plan. To find out what you might need to pay for Onureg with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Onureg?

Onureg (azacitidine tablets) is an FDA (U.S. Food and Drug Administration)-approved medication manufactured by Bristol-Myers Squibb. Onureg is a trademark of Celgene Corporation, a Bristol Myers Squibb company. It is used for patients above 18 years of age with acute myeloid leukemia (AML) who had first complete remission (CR) or complete remission with incomplete blood count recovery (CRi) following intensive induction chemotherapy with or without recovery of blood cell counts, and who are unable to complete intensive curative therapy.

The efficacy of Onureg was investigated in Quazar AML-001, a multicenter, randomized, double-blind, placebo-controlled trial, and based on the overall survival (OS). Clinical trials demonstrate a significant improvement in overall survival for patients randomized to Onureg compared to placebo.

What doses of Onureg are available?

Onureg is available as film-coated tablets, in the following doses: 200 mg or 300 mg.

The recommended dose is 300 mg orally once daily with or without food. Swallow the tablets whole. Take on days 1 to 14 of each 28-day cycle. You should carry on taking Onureg until disease progression or unacceptable levels of toxicity occur. Monitor complete blood count every other week for the first 2 cycles and before starting each cycle thereafter.

Please see full Prescribing Information to ensure safe and effective use of Onureg. Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Onureg active ingredients

Azacitidine is a pyrimidine nucleoside analog of cytidine that inhibits DNA/RNA methyltransferases. Azacitidine is bound into DNA and RNA following uptake at a cellular level and transformation by enzymes to nucleotide triphosphates.

The binding of azacitidine into the DNA of cancer cells in vitro, including acute myeloid leukemia cells, prevents DNA methyltransferases, reduces DNA methylation, and changes gene expression, as well as re-expression of genes regulating tumor suppression and cell growth. The binding of azacitidine into the RNA of cancer cells, including leukemic cells, inhibits RNA methyltransferases, reduces RNA methylation, decreases RNA stability, and decreases the production of protein.

Onureg side effects

The most common side effects and adverse reactions caused by Onureg include:

  • Nausea and vomiting
  • Diarrhea
  • Tiredness or weakness
  • Constipation
  • Abdominal pain
  • Arthralgia (joint pain) and joint pain
  • Pneumonia
  • Decreased appetite
  • Dizziness

In rare instances, Onureg can cause more serious side effects. These can include:

  • Body aches
  • Feeling very tired or weak
  • Unusual headaches
  • Bone marrow suppression
  • Febrile neutropenia
  • New or worsening low platelet counts (thrombocytopenia) – unusual bruising or bleeding
  • New or worsening low white blood cell counts – increased risk of infection

These are not all of the possible side effects of ONUREG. Call your healthcare professional for medical advice about side effects. You may report the side effects of prescription drugs to FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Onureg drug interactions

Onureg can interact with other medications. These include:

  • Allopurinol
  • Amlodipine
  • Centrum Silver (multivitamin with minerals)
  • Escitalopram
  • Glipizide
  • Hydrocodone
  • Lisinopril
  • Lorazepam
  • Metformin
  • Nifedipine
  • Pravastatin
  • Valacyclovir

This list is not exhaustive and other drugs may interact with Onureg. Tell your healthcare provider about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Onureg contraindications

You should not use Onureg if you:

  • Are allergic to the active ingredient azacitidine
  • Are allergic to any of the other ingredients in Onureg
  • Have myelodysplastic syndromes
  • Are pregnant or are planning to become pregnant – females of reproductive potential are advised to use contraception during treatment and for at least 6 months after the last dose. You may need to have a negative pregnancy test before starting this treatment

Talk to your doctor before using Onureg if you:

  • Are taking any of the medications that could interact with Onureg
  • Are breastfeeding or are planning to breastfeed – do not breastfeed for at least one week after your last dose
  • Have kidney disease
  • Have liver disease

Onureg generic

Onureg is the trademark brand name for azacitidine manufactured by Bristol-Myers Squibb. A generic version of azacitidine is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Onureg savings through NiceRx.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.