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Oxlumo Patient assistance program

Is your Oxlumo medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Oxlumo medication with our help.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
  • Next steps after qualifying
  • Uploading documents and billing
  • SSN & billing information
  • Medication delivery time

How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Oxlumo cost savings if eligible

If you are eligible for the Oxlumo patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Oxlumo prescription for just $49 a month, regardless of the retail price of your medication.

Am I eligible for the Oxlumo patient assistance program?

We will review your application to determine whether you are eligible for the Oxlumo patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Oxlumo patient assistance program?

We make it as easy as possible to apply for the Oxlumo patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Oxlumo. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.

If we determine that you may be eligible for Oxlumo assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Oxlumo patient assistance program, and we will automatically request your Oxlumo medication refills for up to 1 year.

Is NiceRx an Oxlumo coupons provider?

We are a service provider that helps eligible individuals access the Oxlumo patient assistance program. That means that we do not offer printable Oxlumo manufacturer coupons, Oxlumo discounts, or free Oxlumo samples. We are not an Oxlumo coupon provider or Oxlumo discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.

Can NiceRx help me get Oxlumo if I have insurance?

We may be able to help you to access Oxlumo patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Oxlumo medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.

How much does Oxlumo cost without insurance?

Oxlumo cost without insurance will vary depending on where you buy it. As a guide, Oxlumo subcutaneous solution (94.5 mg/0.5 mL) usually costs $57,400 for a supply of 0.5 milliliters. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.

How much does Oxlumo cost with insurance?

The copay for Oxlumo with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.

What is Oxlumo?

Oxlumo is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Alnylam Pharmaceuticals, Inc. Oxlumo is a HAO1-directed small interfering ribonucleic acid (siRNA) used for the treatment of primary hyperoxaluria type 1 (PH1) to lower urinary oxalate levels in pediatric and adult patients.

FDA approval was based on results from two multi-national phase three, single-arm, double-blind, open-label, clinical trials, Illuminate-A and Illuminate-B.

PH1 is an ultra-rare disease characterized by the overproduction of oxalate, which can combine with calcium to cause kidney stones and nephrocalcinosis, (calcium deposits in the kidneys). Patients can experience kidney damage, which can lead to kidney failure and the need for dialysis. As kidney function worsens, oxalate can build up and damage other organs, including the heart, bones, skin, eyes, and central nervous system (systemic oxalosis).

What doses of Oxlumo are available?

Oxlumo is available in injection form, in the following doses: 94.5 mg/0.5 mL in a single-dose vial.

Oxlumo is injected under the skin, usually once every 1 to 3 months. Doses are based on body weight in children.

For more information about please see the full prescribing information or speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Oxlumo active ingredients

Lumasiran reduces levels of the glycolate oxidase (GO) enzyme by targeting the hydroxy acid oxidase 1 (HAO1) messenger ribonucleic acid (mRNA) in hepatic cells through RNA interference.

Decreased GO enzyme levels reduce the amount of available glyoxylate, a substrate for the production of oxalate. As the GO enzyme is upstream of the deficient alanine: glyoxylate aminotransferase (AGT) enzyme that causes PH1, the mechanism of action of lumasiran is independent of the underlying AGXT gene mutation.

Oxlumo side effects

The most common adverse reaction of Oxlumo in clinical trials compared to placebo include:

  • Injection site reactions
  • Abdominal pain

Your doctor will assess the benefits of using Oxlumo against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Oxlumo to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Oxlumo drug interactions

No drug interaction studies have been conducted for Oxlumo. Talk to your caregivers about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.

Oxlumo contraindications

You should not use Oxlumo if you:

  • Are allergic to the active ingredient lumasiran
  • Are allergic to any of the other ingredients in Oxlumo

Talk to your doctor before using Oxlumo if you:

  • Are taking any of the medications that could interact with Oxlumo
  • Are pregnant or are planning to become pregnant
  • Are breastfeeding or are planning to breastfeed – Lactation – there are no data on the presence of Oxlumo in human milk

Oxlumo generic

Oxlumo is the trademark brand name for lumasiran manufactured by Alnylam Pharmaceuticals, Inc. A generic version of lumasiran is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Oxlumo savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.