How it works
Get started by filling out the online enrollment application to find out if you are eligible for assistance.
NiceRx verifies your eligibility for medication assistance and notifies you if you are pre-qualified. The pharmaceutical company provides your medication for free, and you only pay our service fee.
We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.
Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address. Final acceptance is determined by the pharmaceutical company.
Your monthly Oxlumo cost savings if eligible
If you are eligible for the Oxlumo patient assistance program, the cost of your medication will be free. We only charge $49 per month for each medication, to cover our service fees. You could receive your Oxlumo prescription for just $49 a month, regardless of the retail price of your medication.
Am I eligible for the Oxlumo patient assistance program?
We will review your application to determine whether you are eligible for the Oxlumo patient assistance program. Each program has its own eligibility criteria which are set by the pharmaceutical companies, however, the factors considered by most programs are:
- I am a permanent, legal resident of the United States or Puerto Rico
- I am uninsured or my insurance doesn’t cover my medication
- I meet certain income eligibility requirements
How do I apply for the Oxlumo patient assistance program?
We make it as easy as possible to apply for the Oxlumo patient assistance program. The first step is to complete our enrollment application. Tell us about any medications you are taking, including Oxlumo. We will also ask for details about your healthcare provider, insurance, and your household income. This information is required by the pharmaceutical manufacturers who ship your medication.
If we determine that you may be eligible for Oxlumo assistance, we will handle the application process for you. We will work directly with your healthcare provider to prepare your application documents. Once we have received the signed application and supporting documents, we will submit them to the patient assistance program on your behalf. Our service continues once you are enrolled in the Oxlumo patient assistance program, and we will automatically request your Oxlumo medication refills for up to 1 year.
Is NiceRx an Oxlumo coupons provider?
We are a service provider that helps eligible individuals access the Oxlumo patient assistance program. That means that we do not offer printable Oxlumo manufacturer coupons, Oxlumo discounts, or free Oxlumo samples. We are not an Oxlumo coupon provider or Oxlumo discount card. Our service extends to assisting eligible individuals to access the medications they need through patient assistance programs.
Can NiceRx help me get Oxlumo if I have insurance?
We may be able to help you to access Oxlumo patient assistance in a variety of circumstances. This includes when your insurance company will not pay for your Oxlumo medication or if you have a high copay or coinsurance responsibility. We may also be able to help you if you do not have insurance. Please apply online to find out more.
How much does Oxlumo cost without insurance?
Oxlumo cost without insurance will vary depending on where you buy it. As a guide, Oxlumo subcutaneous solution (94.5 mg/0.5 mL) usually costs $57,400 for a supply of 0.5 milliliters. With NiceRx you will pay a flat monthly fee of $49, regardless of the retail price of your medication.
How much does Oxlumo cost with insurance?
The copay for Oxlumo with insurance depends on the terms of your healthcare plan. To find out how much this is, your healthcare provider or pharmacist will be able to calculate your copay with your current insurance.
What is Oxlumo?
Oxlumo is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Alnylam Pharmaceuticals, Inc. Oxlumo is a HAO1-directed small interfering ribonucleic acid (siRNA) used for the treatment of primary hyperoxaluria type 1 (PH1) to lower urinary oxalate levels in pediatric and adult patients.
FDA approval was based on results from two multi-national phase three, single-arm, double-blind, open-label, clinical trials, Illuminate-A and Illuminate-B.
PH1 is an ultra-rare disease characterized by the overproduction of oxalate, which can combine with calcium to cause kidney stones and nephrocalcinosis, (calcium deposits in the kidneys). Patients can experience kidney damage, which can lead to kidney failure and the need for dialysis. As kidney function worsens, oxalate can build up and damage other organs, including the heart, bones, skin, eyes, and central nervous system (systemic oxalosis).
What doses of Oxlumo are available?
Oxlumo is available in injection form, in the following doses: 94.5 mg/0.5 mL in a single-dose vial.
Oxlumo is injected under the skin, usually once every 1 to 3 months. Doses are based on body weight in children.
For more information about please see the full prescribing information or speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.
Oxlumo active ingredients
Lumasiran reduces levels of the glycolate oxidase (GO) enzyme by targeting the hydroxy acid oxidase 1 (HAO1) messenger ribonucleic acid (mRNA) in hepatic cells through RNA interference.
Decreased GO enzyme levels reduce the amount of available glyoxylate, a substrate for the production of oxalate. As the GO enzyme is upstream of the deficient alanine: glyoxylate aminotransferase (AGT) enzyme that causes PH1, the mechanism of action of lumasiran is independent of the underlying AGXT gene mutation.
Oxlumo side effects
The most common adverse reaction of Oxlumo in clinical trials compared to placebo include:
- Injection site reactions
- Abdominal pain
Your doctor will assess the benefits of using Oxlumo against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Oxlumo to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.
Oxlumo drug interactions
No drug interaction studies have been conducted for Oxlumo. Talk to your caregivers about all the medicines you take, including prescription drugs and over-the-counter medicines, vitamins, and herbal supplements.
You should not use Oxlumo if you:
- Are allergic to the active ingredient lumasiran
- Are allergic to any of the other ingredients in Oxlumo
Talk to your doctor before using Oxlumo if you:
- Are taking any of the medications that could interact with Oxlumo
- Are pregnant or are planning to become pregnant
- Are breastfeeding or are planning to breastfeed – Lactation – there are no data on the presence of Oxlumo in human milk
Oxlumo is the trademark brand name for lumasiran manufactured by Alnylam Pharmaceuticals, Inc. A generic version of lumasiran is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Oxlumo savings through NiceRx.
The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.