Pluvicto Coupon & Prices

Your monthly Pluvicto cost savings if eligible

If you are eligible for the Pluvicto patient assistance program you can receive your medication for free. Our monthly service fee of $49 per medication covers the cost of our services in applying for the program and requesting your ongoing refills on your behalf. If you obtain your Pluvicto through NiceRx, you will only pay $49 a month regardless of the retail price of your medication.

Am I eligible for the Pluvicto patient assistance program?

You could receive your Pluvicto without paying the full retail price if you meet the eligibility criteria for assistance. The eligibility requirements are set by the pharmaceutical companies that are providing assistance programs. At NiceRx, we review each application individually, although the main factors considered by most programs are:

• I am a permanent, legal resident of the United States or Puerto Rico
• I am uninsured or my insurance doesn’t cover my medication
• I meet certain income eligibility requirements

How do I apply for Pluvicto patient assistance?

We do everything that we can to take the hassle and stress out of applying for patient assistance programs. Simply start by filling in our enrollment application. We will ask for details about your healthcare provider, your insurance, and your household income. This information is required by the pharmaceutical companies you are applying to for assistance. We may also be able to help you access patient assistance for other medications that you have been prescribed, so be sure to tell us about any medications you are taking as well as Pluvicto.

NiceRx will review the information you have provided, and if we determine that you may be eligible for assistance, we will seek to enroll you in the Pluvicto patient assistance program. We will handle the enrollment process for you by working with your healthcare provider and preparing all the required paperwork for your doctor to sign. We will also request your Pluvicto medication refills on your behalf for up to 1 year once you are enrolled in the program.

Is NiceRx a Pluvicto coupon provider?

At NiceRx, we help eligible individuals access the Pluvicto patient assistance program. This means that we are not a Pluvicto coupon, a Pluvicto discount card, or a Pluvicto copay card provider. We do not offer any medication trial offers or free Pluvicto samples.

Can NiceRx help me get Pluvicto cheaper if I have insurance?

We may be able to help you if you have insurance, including if your insurance company will not pay for your Pluvicto medication, or if you have a high copay or coinsurance responsibility. We may even be able to assist if you do not have insurance. Please fill in our enrollment application to find out more.

How much does Pluvicto cost without insurance?

Pluvicto costs without insurance will vary depending on how much you buy and the retailer you buy it from. As a guide, Pluvicto will typically cost around $42,500 per cycle. If you obtain your medication through NiceRx, you will pay a flat monthly rate of $49 per medication regardless of its retail price.

How much does Pluvicto cost with insurance?

The copay of Pluvicto will vary in line with the specific terms of your healthcare plan. For further details about what you may need to pay, your insurance provider or pharmacist will be able to calculate the copay costs with your current insurance.

What is Pluvicto?

Pluvicto is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Novartis. Pluvicto has FDA approval as a targeted radioligand therapy for the treatment of adult patients with a certain type of advanced cancer called prostate-specific membrane antigen, PSMA-positive metastatic castration-resistant prostate cancer (PSMA-positive mCRPC) that has spread to other parts of the body.

What doses of Pluvicto are available?

Pluvicto is available in injection form, in the following doses: 1,000 MBq/mL (27 mCi/mL) in a single-dose vial.

Patients are selected for treatment using Locametz or an approved PSMA-11 imaging agent based on PSMA expression in tumors. Because Pluvicto is a radiopharmaceutical your caregiver will take appropriate safety measures to minimize radiation exposure including waterproof gloves and effective radiation shielding. Make sure you drink plenty of water before administration of Pluvicto in order to urinate as often as possible during the first hours after administration.

Pluvicto is given as an intravenous injection every 6 weeks for up to 6 doses, or until disease progression or unacceptable toxicity. Always speak with your healthcare provider about any changes to your dose so they can monitor and evaluate your condition.

Pluvicto active ingredients

Pluvicto contains lutetium Lu 177 vipivotide tetraxetan, (formerly called 177 Lu-PSMA-617) as the active ingredient.

Efficacy of Pluvicto was evaluated in VISION, a clinical trial that evaluated Pluvicto plus the best standard of care in men with progressive, PSMA-positive mCRPC. Patients were required to have received at least one androgen receptor (AR) pathway inhibitor, and 1 or 2 prior taxane-based chemotherapy regimens. Patients received Pluvicto 7.4 GBq (200 mCi) every 6 weeks for up to a total of 6 doses plus BSoC or BSoC alone.

The trial showed a significant improvement in the primary endpoints of overall survival (OS) and radiographic progression-free survival (rPFS). Interpretation of the magnitude of the rPFS effect was limited due to a high degree of censoring from early dropout in the control arm.

Pluvicto side effects

The most common side effects of Pluvicto in clinical trials include:

• Fatigue
• Dry mouth, nausea
• Anemia
• Decreased appetite, and constipation
• Decreased lymphocytes decreased hemoglobin, decreased leukocytes, decreased platelets, decreased calcium, and decreased sodium

In rare instances, Pluvicto can cause more serious side effects. These can include:

• Risk from radiation exposure
• Myelosuppression
• Renal toxicity
• Embryo-fetal toxicity – male patients with female partners of reproductive potential should use effective contraception
• May cause temporary or permanent infertility

Your doctor will assess the benefits of using Pluvicto against your risk of adverse events. Patients are encouraged to report negative side effects or adverse reactions of Pluvicto to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Pluvicto drug interactions

Other drugs may interact with Pluvicto, including prescription drugs and over-the-counter medicines, vitamins, and herbal products. Tell your health care provider about all of your medication including any supplements you are taking.

Pluvicto contraindications

You should not use Pluvicto if you:

• Are allergic to the active ingredient lutetium Lu 177 vipivotide tetraxetan
• Are allergic to any of the other ingredients in Pluvicto
• Are pregnant or are planning to become pregnant

Talk to your doctor before using Pluvicto if you:

• Are taking any of the medications that could interact with Pluvicto
• Have low blood cell counts
• Have signs of myelosuppression
• Have kidney problems
• Have any other type of cancer or treatment for cancer
• Are breastfeeding or are planning to breastfeed

Pluvicto generic

Pluvicto is the trademark brand name for lutetium Lu 177 vipivotide tetraxetan manufactured by Novartis. A generic version of lutetium Lu 177 vipivotide tetraxetan is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Pluvicto savings through NiceRx.