Protopic Coupon & Prices

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Medically reviewed by  Jamie Winn, PharmD

Is NiceRx a Protopic coupon provider?

NiceRx does not provide Protopic coupons, discount cards or copay cards. We do not offer printable Protopic manufacturer coupons, Protopic discounts, rebates, Protopic savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs.

Protopic patient assistance program

Patient assistance programs are typically sponsored by pharmaceutical companies and provide free or discounted medications to individuals with low income who are uninsured or under-insured and meet the eligibility criteria that vary by program. There are currently no known patient assistance programs for this medication.

How much does Protopic cost without insurance?

Protopic prices without insurance will vary by retailer. As a guide, Protopic topical ointment 0.03% will typically cost around $315 for 30 grams.

How much does Protopic cost with insurance?

Your individual healthcare plan will determine the copay of Protopic with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Protopic?

Protopic (tacrolimus ointment) is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Astellas. Protopic is a topical macrolide immunosuppressant that works by reducing your body’s natural immune system from functioning normally. This helps to slow down the growth of atopic dermatitis (eczema) on your skin.

Protopic ointment is used short-term to treat skin conditions such as moderate to severe eczema in adults and children at least 2 years of age. It is not recommended for long-term use or in people with a weak immune system.

What doses of Protopic are available?

Protopic is available in an ointment form, in the following doses: 0.03%, 0.1%, and 0.01%.

Apply a thin layer of Protopic ointment to the affected areas using the smallest amount needed to control the symptoms of eczema. Only use this medicine on skin affected by eczema. Do not apply to an area that may be affected by skin cancer. Avoid sun exposure, sun lamps, tanning beds, and treatments with ultraviolet light, and wear loose clothing over the application site when outdoors. Do not use sunscreen on treated areas unless your doctor has told you to.

Some people using tacrolimus skin treatments have developed skin cancer or lymphoma. It is not known however if either of these medicines causes cancer.

Please read the full prescribing information and medication guide and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Protopic active ingredients

Protopic contains tacrolimus, a topical calcineurin inhibitor, as the active ingredient.

Protopic side effects

The most common side effects of Protopic in clinical trials include:

  • Burning sensation
  • Stinging, itching, or tingling especially during the first few days of treatment
  • Acne, redness, or crusting around your hair follicles
  • Upset stomach
  • Flu-like symptoms – runny or stuffy nose, cough, headache, muscle pain, swollen glands

In rare instances, Protopic can cause more serious adverse effects. These can include:

  • New or worsened skin symptoms (warts, unusual rash or skin lesions, blistering)
  • Moles that change size or color
  • Symptoms of a viral skin infection – cold sores around your mouth, shingles, skin sores or blisters, scabs, itching, tingling

Your doctor will assess the benefits of using Protopic against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Protopic to the FDA. Visit, or call 1-800-FDA-1088.

Protopic drug interactions

Protopic can interact with other medications. These include:

  • Nutritional supplements, and herbal products
  • Antifungals such as fluconazole, itraconazole, and ketoconazole
  • Calcium channel blockers such as diltiazem and verapamil
  • Erythromycin and other ointments, creams, or lotions

This list is not exhaustive and other prescription drugs may interact with Protopic.

Protopic contraindications

You should not use Protopic if you:

  • Are allergic to the active ingredient tacrolimus
  • Have had an allergic reaction to any of the other ingredients in Protopic
  • Are younger than 2 years of age
  • Are breastfeeding or are planning to breastfeed

Talk to your doctor before using Protopic if you:

  • Are taking any of the medications that could interact with Protopic
  • Have skin cancer
  • Have a bacterial or viral skin infection (including herpes or chickenpox)
  • Have Netherton’s syndrome
  • Have a weak immune system for any reason
  • Have kidney disease
  • Are pregnant or are planning to become pregnant

Protopic generic

Protopic is the trademark brand name for tacrolimus manufactured by Astellas. A generic version of tacrolimus is available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Protopic savings through NiceRx.

Related conditions

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.