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Ravicti Patient assistance program

Is your Ravicti medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your Ravicti medication with our help.

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  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: Your medication is delivered straight to your door
  • NiceRx Benefit
    Ongoing refills: Your medication is refilled automatically
  • NiceRx Benefit
    Secure: Your personal and medical information is safe with us
  • NiceRx Benefit
    Convenient: We manage the whole process and we’re here to assist you
  • NiceRx Benefit
    Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

How it works

  • Enroll online

    Get started by filling out the online enrollment application to find out if you are eligible for assistance.

  • Pre-qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Submit documents

    We will request documents to be submitted by you and your healthcare provider that are required by the pharmaceutical company to complete your enrollment.

  • Receive medication

    Once approved, the pharmaceutical company typically ships a 90-day supply of medication to your home or healthcare provider’s address.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Ravicti cost savings if eligible

If you are eligible to receive your Ravicti prescription through the patient assistance program, your medication will be free. We charge a flat monthly service fee of $49 per medication to cover the cost of our services.

Am I eligible for Ravicti patient assistance?

To be eligible for the Ravicti patient assistance program, you will need to meet specific eligibility criteria set by the pharmaceutical company. At NiceRx, we review each Ravicti enrollment application individually. The main factors considered are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Ravicti patient assistance program?

Applying for the Ravicti patient assistance program through NiceRx is simple. Begin by completing the enrollment application on our website. We will ask for details about your healthcare provider, your insurance plan, and your household income. This information is required by the pharmaceutical manufacturers that supply your medication. We may be able to help you access patient assistance for other medications as well as Ravicti, so please tell us about any medications that you have been prescribed.

If we determine that you may be eligible for Ravicti assistance, we will handle the full enrollment process on your behalf. We will work with your healthcare provider to prepare and submit all the documents required for you to enroll. If you are successfully enrolled in the Ravicti patient assistance program, we will also request your Ravicti medication refills on your behalf for up to 1 year. At the end of your enrollment period, we will contact you for updated details and seek to re-enroll you in the program.

Is NiceRx a Ravicti coupon provider?

NiceRx does not provide Ravicti coupons, discount cards or copay cards. We do not offer printable Ravicti manufacturer coupons, Ravicti discounts, rebates, Ravicti savings cards, trial offers, or free samples. We are a service provider that helps eligible individuals access patient assistance programs. Our service cost is $49 a month per medication, so you will likely save more on your Ravicti medication with NiceRx.

Can NiceRx help me get Ravicti cheaper if I have insurance?

NiceRx may be able to help you access Ravicti patient assistance if:

  • You have a high copay or coinsurance responsibility for Ravicti
  • Your insurance company will not pay for your Ravicti prescription
  • You do not have insurance

Complete your enrollment application online to find out more.

How much does Ravicti cost without insurance?

Ravicti prices without insurance will vary by retailer. As a guide, Ravicti oral liquid (1.1 g/mL) will typically cost around $5,500 for 25 milliliters.

How much does Ravicti cost with insurance?

Your individual healthcare plan will determine the copay of Ravicti with insurance. To find out what you will need to pay, contact your pharmacist or insurance provider. They will be able to calculate your copay with your current insurance.

What is Ravicti?

Ravicti is an FDA (U.S. Food and Drug Administration) approved medication distributed by Horizon Therapeutics plc. Ravicti (glycerol phenylbutyrate) is a nitrogen-binding agent indicated for the chronic management of patients 2 years of age and older with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.

Ravicti must be used with dietary protein restrictions (low-protein diet) and, in some cases, dietary supplements, such as essential amino acids, arginine, citrulline, and protein-free calorie supplements.

Ravicti is not recommended for the treatment of acute hyperammonemia (sudden rise of blood ammonia levels) in patients with UCDs, or for the treatment of N-acetylglutamate synthase (NAGS) deficiency.

What doses of Ravicti are available?

Ravicti is available in oral liquid form, in the following doses: 1.1 g/mL of glycerol phenylbutyrate.

Your dose of Ravicti depends on your diet, height, and weight. Regular blood tests are needed to adjust your dose. Your total daily dose of Ravicti should be divided into equal amounts and taken with each meal. Ravicti may be a life-long treatment unless you have a successful liver transplant. If you switch from sodium phenylbutyrate (Buphenyl) to Ravicti, your dose will not be the same. Follow your doctor’s dosing instructions very carefully. If you cannot swallow see the instructions on the administration of Ravicti by nasogastric tube or gastrostomy tube.

Please read the full medication guide and always speak with a healthcare professional about any changes to your dose so they can monitor and evaluate your condition.

Ravicti active ingredients

The active ingredient, glycerol phenylbutyrate, is converted to phenylacetate in the body. Phenylacetate attaches to glutamine found in proteins to form a substance that the kidneys can remove from the body. Removal of proteins decreases the levels of nitrogen in the body, reducing the amount of ammonia produced.

Ravicti side effects

The most common side effects of Ravicti in clinical trials include:

  • Diarrhea
  • Flatulence
  • Headache
  • Stomach pain, decreased appetite, indigestion, or heartburn
  • Vomiting
  • Tiredness
  • High blood levels of ammonia

In rare instances, Ravicti can cause more serious adverse effects. These can include:

  • Neurotoxicity
  • Reduced phenylbutyrate absorption in pancreatic insufficiency or intestinal malabsorption

Your doctor will assess the benefits of using Ravicti against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Ravicti to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Ravicti drug interactions

Ravicti can interact with other medications. These include:

  • Corticosteroids, valproic acid, or haloperidol may increase plasma ammonia levels – monitor ammonia levels closely
  • Probenecid – may affect renal excretion of metabolites of Ravicti
  • CYP3A4 substrates with narrow therapeutic index – alfentanil, quinidine, cyclosporine
  • Midazolam

This list is not exhaustive and other prescription drugs may interact with Ravicti.

Ravicti contraindications

You should not use Ravicti if you:

  • Are allergic to the active ingredient glycerol phenylbutyrate
  • Are allergic to any of the other ingredients in Ravicti
  • Are less than 2 months of age
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Ravicti if you:

  • Are taking any of the medications that could interact with Ravicti
  • Have hepatic impairment
  • Have kidney disease
  • Have a pancreas disorder
  • Have a stomach or intestinal disorder
  • Have a condition called NAGS (N-acetylglutamate synthase) deficiency
  • Are breastfeeding or are planning to breastfeed

Ravicti generic

Ravicti is the trademark brand name for glycerol phenylbutyrate distributed by Horizon Therapeutics plc. A generic version of glycerol phenylbutyrate is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Ravicti savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking the different programs and filling out all the required paperwork for each program. Subject to medication availability.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.