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RediTrex Patient assistance program

Is your RediTrex medication too expensive? Start receiving your medication for only $49 per month.*

Complete a free online enrollment application to find out if you’re eligible to pay only $49 per month for your RediTrex medication with our help.

Get started today
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf
  • Secure: Your personal and medical information is safe with us
  • Convenient: We manage the whole process and we’re here to assist you
  • Ongoing refills: We request your medication refills on your behalf

NiceRx works with your healthcare provider to help you access affordable medications directly from U.S. pharmaceutical companies.

An introduction to NiceRx

Play video (01:52)
  • An introduction to NiceRx
  • Next steps after qualifying
  • Uploading documents and billing
  • SSN & billing information
  • Medication delivery time

How it works

  • Apply Online

    Get started by filling out the online enrollment application to find out if you are eligible.

  • Qualification

    NiceRx verifies your eligibility for medication assistance and notifies you if you are qualified. The pharmaceutical company provides your medication for free and you only pay our service fee.

  • Upload Documents

    You may be required to submit further information and documents required by the pharmaceutical company which can be securely uploaded online.

  • Application Created

    Your application is created and sent to your doctor for signature. At this stage, you will be billed $49 and will not be billed again until you receive your first medication delivery.

  • Receive Medication

    Your application is sent to the pharmaceutical company. You will be billed again once you receive your medication. We handle the entire ordering process including requesting ongoing refills.

Medically reviewed by  Jamie Winn, PharmD

Your monthly Reditrex cost savings if eligible

The Reditrex patient assistance program can provide your medication for free. We simply charge $49 per month for each medication to cover the cost of our services. With NiceRx, you will only pay $49 to obtain your Reditrex, regardless of the retail price.

Am I eligible for the Reditrex patient assistance program?

To find out if you are eligible for Reditrex assistance you can apply online using our enrollment application. Each pharmaceutical company sets its eligibility criteria, and we will review your application individually to determine if you may be eligible. The three main factors to consider are:

  • I am a permanent, legal resident of the United States or Puerto Rico
  • I am uninsured or my insurance doesn’t cover my medication
  • I meet certain income eligibility requirements

How do I apply for the Reditrex patient assistance program?

Our application process aims to make it as easy as possible to apply for the Reditrex patient assistance program. The first step is to complete our online enrollment application. We will ask you for details about your healthcare provider, your insurance plan, and your household income as this information is required by the pharmaceutical companies. We may be able to help you apply for other patient assistance programs too, so be sure to tell us about any medications you are taking as well as Reditrex.

NiceRx will review your application and determine whether you may be eligible for Reditrex assistance. If so, we will handle the full enrollment process for you and prepare all required documents for your healthcare provider to sign. Once you are successfully enrolled in the Reditrex patient assistance program, we will help you manage your prescription refills by requesting refills on your behalf throughout your enrollment period. At the end of your enrollment period, we will contact you for updated information and seek to re-enroll you so you can continue to access affordable Reditrex.

Is NiceRx a Reditrex coupon provider?

NiceRx is a service provider that helps eligible individuals access the Reditrex patient assistance program. We do not offer trial offers or free Reditrex samples. When obtaining your medication through NiceRx, you will only pay $49 a month per medication. This will likely save you more money than if you were to use Reditrex coupons, discount cards, or Reditrex copay cards.

Can NiceRx help me get Reditrex cheaper if I have insurance?

NiceRx may be able to help you if your insurance company will not pay for your Reditrex medication. We may also be able to help if you have a high copay or coinsurance responsibility. Whether you have insurance or not, apply online using our enrollment application to find out more.

How much does Reditrex cost without insurance?

Reditrex prices without insurance will vary depending on how much you buy. Prices will also vary by retailer. As a guide, Reditrex subcutaneous solution (7.5 mg/0.3 mL) typically costs $340 for 1.2 milliliters.

How much does Reditrex cost with insurance?

The copay for Reditrex will vary by the terms of your healthcare plan. To find out what you might need to pay for Reditrex with insurance, your insurance provider or pharmacist will be able to help you calculate the copay costs with your current insurance.

What is Reditrex?

Reditrex is an FDA (U.S. Food and Drug Administration) approved medication manufactured by Cumberland Pharmaceuticals Inc. RediTrex is a folate analog metabolic inhibitor used for the:

  • Management of severe, active rheumatoid arthritis (RA) and polyarticular juvenile idiopathic arthritis (pJIA) in patients who are not tolerant of or have had an inadequate response to first-line therapy
  • Control of severe symptoms of psoriasis in adults who are not fully responsive to other therapy

RediTrex is not recommended for the treatment of neoplastic diseases

What doses of Reditrex are available?

Reditrex is available in injection form as single-dose prefilled syringes delivering methotrexate in the following dosage strengths: 7.5mg, 10 mg, 12.5 mg, 15 mg, 17.5 mg, 20 mg, 22.5 mg and 25 mg.

RediTrex is for once weekly subcutaneous administration in the abdomen or thigh. The starting dose of methotrexate for rheumatoid arthritis is 7.5 mg once weekly. For polyarticular juvenile idiopathic arthritis the starting dose is 10 mg/m2 once weekly. For psoriasis the starting dose is 10 to 25 mg once weekly of an oral, intramuscular, subcutaneous, or intravenous formulation. Otrexup (methotrexate subcutaneous injection) and Rasuvo (methotrexate subcutaneous auto-injector) are alternative brands of methotrexate.

You should take a folic acid supplement with methotrexate to prevent folate deficiency. Taking methotrexate can reduce levels of folate in your body. A lack of folate can lead an upset stomach, low blood cell counts, fatigue, muscle weakness, mouth sores, liver toxicity and central nervous system symptoms.

Please see the full prescribing information for the complete boxed warning, and always speak with a healthcare professional for medical advice about any changes to your dose so they can monitor and evaluate your condition.

Reditrex active ingredients

Reditrex contains methotrexate as the active ingredient.

Reditrex side effects

The most common side effects of Reditrex in clinical trials include:

  • Nausea, stomach pain, dyspepsia, diarrhea, vomiting
  • Stomatitis/mouth sores, rash, nasopharyngitis
  • Hair loss
  • Liver function test abnormalities
  • Headache, dizziness
  • Bronchitis
  • Thrombocytopenia, leucopenia, pancytopenia
  • Photosensitivity, and burning of skin lesions

In rare instances, Reditrex can cause more serious side effects. These can include:

  • Serious toxic reactions and death – bone marrow, liver, lung, skin, and kidney toxicities
  • Embryo-fetal toxicity, including fetal death
  • Unexpectedly severe bone marrow suppression, aplastic anemia, and gastrointestinal toxicity when given with some nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Hepatotoxicity, fibrosis, and cirrhosis
  • Interstitial pneumonitis
  • Pulmonary symptoms (especially a dry cough) may require interruption of treatment
  • Diarrhea, ulcerative stomatitis, hemorrhagic enteritis, and death
  • Severe, occasionally fatal, skin reactions
  • Potentially fatal opportunistic infections may occur

Your doctor will assess the benefits of using Reditrex against your risk of side effects. Patients are encouraged to report negative side effects or adverse reactions of Reditrex to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Reditrex drug interactions

Reditrex can interact with other medications. These include:

  • NSAIDs – ibuprofen, diclofenac, naproxen
  • Steroids
  • Proton pump inhibitors – omeprazole
  • Certain vaccinations

This list is not exhaustive and other prescription drugs may interact with Reditrex.

Reditrex contraindications

You should not use Reditrex if you:

  • Are allergic to the active ingredient methotrexate
  • Are allergic to any of the other ingredients in Reditrex
  • Suffer from alcoholism
  • Have liver disease or any other liver problems
  • Have immunodeficiency syndromes (weak immune system)
  • Are pregnant or are planning to become pregnant

Talk to your doctor before using Reditrex if you:

  • Are taking any of the medications that could interact with Reditrex
  • Have anemia, leukopenia, or thrombocytopenia (low platelet blood level)
  • Have kidney disease
  • Have pleural effusion
  • Have diabetes or
  • Have ulcerative colitis
  • Are breastfeeding or are planning to breastfeed

Reditrex generic

Reditrex is the trademark brand name for methotrexate manufactured by Cumberland Pharmaceuticals Inc. A generic version of methotrexate is not available. Generic drugs are generally cheaper than brand-name drugs, but you can still find Reditrex savings through NiceRx.

*Qualifying persons may obtain medications directly from patient assistance programs without any out-of-pocket cost (or for less than $49 per medication). However, our monthly flat rate of just $49 per medication spares you the hassle of tracking down the different programs and filling out all the required paperwork for each program.

Enrollees enjoy a full-service solution, as NiceRx assists them and their physicians with the entire process. We prepare all required documents for the physician to sign, help enrollees manage all prescription refills, monitor eligibility criteria, and maintain enrollment.

**If you do not receive medications because you were determined to be ineligible for the prescription assistance by the applicable pharmaceutical companies and you have a letter of denial, we will refund any fees you paid toward medications for which you did not qualify to receive prescription assistance (“Refund”).

To receive a refund, you must send the letter of denial to us by fax to 888-517-7444, or by e-mail to [email protected] within 30 days of your receipt of such letter. The Refund is your sole and exclusive remedy for any fees you may wish to dispute.

The content on this website is intended for information purposes only. It does not constitute medical advice. The information on this website should not be relied upon and is not a substitute for professional medical advice. You should always speak to your doctor regarding the risks and benefits of any treatment.